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Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 859–872.
Published: 22 December 2021
...Lucia Iannotta; Elisa Greggio Leucine-rich repeat kinase 2 (LRRK2) is a complex GTPase/kinase orchestrating cytoskeletal dynamics and multiple steps of the endolysosomal pathway through interaction with a host of partners and phosphorylation of a subset of Rab GTPases. Mutations in LRRK2 cause late...