... 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 autophagy AMPK cancer ER stress mTOR ULK1 Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) senses and integrates a variety of inputs, including growth signals, amino acid levels...

... the ER lumen. Signalling sensors within the ER detect perturbations within the lumen (ER stress) and employ downstream signalling cascades that engage effector mechanisms to restore homeostasis. The most studied signalling mechanism that the ER employs is the unfolded protein response (UPR), which...

... the scope of SA functions beyond plant immunity to include plant growth and development, endoplasmic reticulum (ER) stress, DNA repair and homologous recombination. Finally, we shed light on the roles of SA in epigenetically controlled transgenerational immune memory that has long-term benefits for plants...