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Keywords: DNMT3B
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Essays Biochem (2019) 63 (6): 773–783.
Published: 14 November 2019
...). The hallmark of this syndrome is hypomethylation of pericentromeric satellite repeats, with mutations in four genes: DNMT3B, ZBTB24, CDCA7 and HELLS , being linked to the disease. Here, we discuss recent progress in understanding the molecular interactions between these genes and consider current evidence...