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Keywords: 3D genome
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Essays Biochem (2020) 64 (6): 907–918.
Published: 07 December 2020
...(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 3D genome chromatin interaction gene promoter RBP transcription regulation The genome comprises all genetic codes for the entire lifecycle of higher organisms, but first it needs to be read out...
Includes: Supplementary data
Essays Biochem (2019) 63 (1): 157–165.
Published: 02 April 2019
... regulation. The CCCTC-binding factor (CTCF) is a DNA binding factor capable of regulating not only the 3D genome organization, but also key aspects of gene expression, including transcription activation and repression, RNA splicing, and enhancer/promoter insulation. A growing body of evidence proposes...