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Keywords: 26S Proteasome
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Essays Biochem (2022) 66 (2): 123–133.
Published: 05 August 2022
... of environmental stress. A key component of the UPS are ubiquitin ligases (or E3s) that catalyze the attachment of ubiquitin molecules to select substrate proteins, which are then recognized by the 26S proteasome for degradation. With the identification of substrate proteins, a growing number of E3s are shown...