1-50 of 95
Molecular Bases of Health & Disease
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning

Gwo-Jiunn H. Hwang, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (5): 893–901.
https://doi.org/10.1042/EBC20230010
Published: 13 September 2023
View article titled, Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning
Open the PDF for Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning in another window
Articles

DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling

Otto P.G. Wheeler, Leonie Unterholzner
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20220241.
https://doi.org/10.1042/EBC20220241
Published: 03 August 2023
View article titled, DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling
Open the PDF for DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling in another window
Articles

The role of IFN-γ-signalling in response to immune checkpoint blockade therapy

Chun Wai Wong, Yang Yu Huang, Adam Hurlstone
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20230001.
https://doi.org/10.1042/EBC20230001
Published: 28 July 2023
View article titled, The role of IFN-γ-signalling in response to immune checkpoint blockade therapy
Open the PDF for The role of IFN-γ-signalling in response to immune checkpoint blockade therapy in another window
Articles

A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment

Mirjam Czjzek, Elizabeth Ficko-Blean, Jean-Guy Berrin
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (3): 325–329.
https://doi.org/10.1042/EBC20230004
Published: 18 April 2023
View article titled, A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment
Open the PDF for A special issue of Essays in Biochemistry on current advances about CAZymes and their impact and key role in human health and environment in another window
Articles

A special issue of Essays in Biochemistry on structural mass spectrometry

Hannah M. Britt, Rebecca Beveridge, Antonio N. Calabrese
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 147–149.
https://doi.org/10.1042/EBC20230006
Published: 29 March 2023
View article titled, A special issue of Essays in Biochemistry on structural mass spectrometry
Open the PDF for A special issue of Essays in Biochemistry on structural mass spectrometry in another window
Articles

Structural mass spectrometry approaches to understand multidrug efflux systems

Benjamin Russell Lewis, Ryan Lawrence, Dietmar Hammerschmid, Eamonn Reading
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (2): 255–267.
https://doi.org/10.1042/EBC20220190
Published: 29 March 2023
View article titled, Structural mass spectrometry approaches to understand multidrug efflux systems
Open the PDF for Structural mass spectrometry approaches to understand multidrug efflux systems in another window
Articles

Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R

Paula Beltran-Lobo, Matthew J. Reid, Maria Jimenez-Sanchez, Alexei Verkhratsky, Beatriz G. Perez-Nievas, Wendy Noble
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 119–130.
https://doi.org/10.1042/EBC20220079
Published: 03 March 2023
View article titled, Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R
Open the PDF for Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X 7 R in another window
Articles

Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

Jens V. Andersen, Arne Schousboe, Petrine Wellendorph
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 77–91.
https://doi.org/10.1042/EBC20220208
Published: 03 March 2023
View article titled, Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling
Open the PDF for Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling in another window
Articles

A special issue in Essays in Biochemistry on astrocytes—more than a neuronal support network

Juan P. Bolaños
Journal: Essays in Biochemistry
Essays Biochem (2023) 67 (1): 1–2.
https://doi.org/10.1042/EBC20230005
Published: 03 March 2023
View article titled, A special issue in Essays in Biochemistry on astrocytes—more than a neuronal support network
Open the PDF for A special issue in Essays in Biochemistry on astrocytes—more than a neuronal support network in another window
Articles

Crossroads between copper ions and amyloid formation in Parkinson’s disease

Pernilla Wittung-Stafshede
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 977–986.
https://doi.org/10.1042/EBC20220043
Published: 16 December 2022
View article titled, Crossroads between copper ions and amyloid formation in Parkinson’s disease
Open the PDF for Crossroads between copper ions and amyloid formation in Parkinson’s disease in another window
Articles

Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates

Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
https://doi.org/10.1042/EBC20220052
Published: 16 December 2022
View article titled, Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates
Open the PDF for Biological soft matter: intrinsically disordered proteins in liquid–liquid phase separation and biomolecular condensates in another window
Articles

Different states and the associated fates of biomolecular condensates

Srivastav Ranganathan, Junlang Liu, Eugene Shakhnovich
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 849–862.
https://doi.org/10.1042/EBC20220054
Published: 16 December 2022
View article titled, Different states and the associated fates of biomolecular condensates
Open the PDF for Different states and the associated fates of biomolecular condensates in another window
Articles

How phosphorylation impacts intrinsically disordered proteins and their function

Estella A. Newcombe, Elise Delaforge, Rasmus Hartmann-Petersen, Karen Skriver, Birthe B. Kragelund
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 901–913.
https://doi.org/10.1042/EBC20220060
Published: 16 December 2022
View article titled, How phosphorylation impacts intrinsically disordered proteins and their function
Open the PDF for How phosphorylation impacts intrinsically disordered proteins and their function in another window
Articles

The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer

Mayra A. Marques, Guilherme A.P. de Oliveira, Jerson L. Silva
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1023–1033.
https://doi.org/10.1042/EBC20220064
Published: 16 December 2022
View article titled, The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer
Open the PDF for The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer in another window
Articles

Phase separation and other forms of α-Synuclein self-assemblies

Manisha Poudyal, Arunima Sakunthala, Semanti Mukherjee, Laxmikant Gadhe, Samir K Maji
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 987–1000.
https://doi.org/10.1042/EBC20220055
Published: 16 December 2022
View article titled, Phase separation and other forms of α-Synuclein self-assemblies
Open the PDF for Phase separation and other forms of α-Synuclein self-assemblies in another window
Articles

Shapeshifting tau: from intrinsically disordered to paired-helical filaments

Kurtis Mengham, Youssra Al-Hilaly, Sebastian Oakley, Kamillia Kasbi, Mahmoud B. Maina, Louise C. Serpell
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1001–1011.
https://doi.org/10.1042/EBC20220150
Published: 16 December 2022
View article titled, Shapeshifting tau: from intrinsically disordered to paired-helical filaments
Open the PDF for Shapeshifting tau: from intrinsically disordered to paired-helical filaments in another window
Articles

Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation

Si Wu, Jitao Wen, Sarah Perrett
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 891–900.
https://doi.org/10.1042/EBC20220148
Published: 16 December 2022
View article titled, Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation
Open the PDF for Unravelling the microscopic characteristics of intrinsically disordered proteins upon liquid–liquid phase separation in another window
Articles

Unconventional R proteins in the botanical tribe Triticeae

Naveenkumar Athiyannan, Lamia Aouini, Yajun Wang, Simon G. Krattinger
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (5): 561–569.
https://doi.org/10.1042/EBC20210081
Published: 30 September 2022
View article titled, Unconventional R proteins in the botanical tribe Triticeae
Open the PDF for Unconventional R proteins in the botanical tribe Triticeae in another window
Articles

Perspective on pros and cons of microlearning in health education

Eser Yıldırım Sozmen
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 39–44.
https://doi.org/10.1042/EBC20210047
Published: 29 April 2022
View article titled, Perspective on pros and cons of microlearning in health education
Open the PDF for Perspective on pros and cons of microlearning in health education in another window
Articles

Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort

Shabana Cassambai, Hannah Bridge, Palak K. Gill, Similoluwa Shobaloju, Tiziana Sgamma, Jo V. Rushworth
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 29–37.
https://doi.org/10.1042/EBC20210051
Published: 29 April 2022
View article titled, Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort
Open the PDF for Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort in another window
Articles

Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts

Torben Lund, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 45–51.
https://doi.org/10.1042/EBC20210053
Published: 29 April 2022
View article titled, Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts
Open the PDF for Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts in another window
Articles

Case study: Biochemistry without borders: a case study utilising infographics

Michelle A. Sahai, Anna Ivanova
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 65–73.
https://doi.org/10.1042/EBC20210040
Published: 29 April 2022
View article titled, Case study: Biochemistry without borders: a case study utilising infographics
Open the PDF for Case study: Biochemistry without borders: a case study utilising infographics in another window
Articles

Cryo-EM structures of τ filaments from human brain

Michel Goedert
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 949–959.
https://doi.org/10.1042/EBC20210025
Published: 22 December 2021
View article titled, Cryo-EM structures of τ filaments from human brain
Open the PDF for Cryo-EM structures of τ filaments from human brain in another window
Articles

LRRK2 signaling in neurodegeneration: two decades of progress

Lucia Iannotta, Elisa Greggio
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 859–872.
https://doi.org/10.1042/EBC20210013
Published: 22 December 2021
View article titled, LRRK2 signaling in neurodegeneration: two decades of progress
Open the PDF for LRRK2 signaling in neurodegeneration: two decades of progress in another window
Articles

PINK1 signalling in neurodegenerative disease

Daniel R. Whiten, Dezerae Cox, Carolyn M. Sue
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 913–923.
https://doi.org/10.1042/EBC20210036
Published: 22 December 2021
View article titled, PINK1 signalling in neurodegenerative disease
Open the PDF for PINK1 signalling in neurodegenerative disease in another window
Articles

Vesicular dysfunction and pathways to neurodegeneration

Patrick A. Lewis
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 941–948.
https://doi.org/10.1042/EBC20210034
Published: 22 December 2021
View article titled, Vesicular dysfunction and pathways to neurodegeneration
Open the PDF for Vesicular dysfunction and pathways to neurodegeneration in another window
Articles

Rab GTPases in Parkinson's disease: a primer

Antonio Jesús Lara Ordóñez, Rachel Fasiczka, Yahaira Naaldijk, Sabine Hilfiker
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 961–974.
https://doi.org/10.1042/EBC20210016
Published: 22 December 2021
View article titled, Rab GTPases in Parkinson's disease: a primer
Open the PDF for Rab GTPases in Parkinson's disease: a primer in another window
Articles

ATP-binding cassette transporters and neurodegenerative diseases

Jared S. Katzeff, Woojin Scott Kim
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 1013–1024.
https://doi.org/10.1042/EBC20210012
Published: 22 December 2021
View article titled, ATP-binding cassette transporters and neurodegenerative diseases
Open the PDF for ATP-binding cassette transporters and neurodegenerative diseases in another window
Articles

Glucocerebrosidase dysfunction in neurodegenerative disease

Sarah M. Brooker, Dimitri Krainc
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 873–883.
https://doi.org/10.1042/EBC20210018
Published: 22 December 2021
View article titled, Glucocerebrosidase dysfunction in neurodegenerative disease
Open the PDF for Glucocerebrosidase dysfunction in neurodegenerative disease in another window
Articles

Retromer dependent changes in cellular homeostasis and Parkinson's disease

Zhe Yang, Zebin Li, Rohan D. Teasdale
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 987–998.
https://doi.org/10.1042/EBC20210023
Published: 22 December 2021
View article titled, Retromer dependent changes in cellular homeostasis and Parkinson's disease
Open the PDF for Retromer dependent changes in cellular homeostasis and Parkinson's disease in another window
Articles

Roles of steroid receptors in the lung and COVID-19

Damien A. Leach, Greg N. Brooke, Charlotte L. Bevan
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1025–1038.
https://doi.org/10.1042/EBC20210005
Published: 26 November 2021
View article titled, Roles of steroid receptors in the lung and COVID-19
Open the PDF for Roles of steroid receptors in the lung and COVID-19 in another window
Articles

Estrogen receptor actions in colitis

Erika L. Garcia-Villatoro, Clinton D. Allred
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1003–1013.
https://doi.org/10.1042/EBC20210010
Published: 26 November 2021
View article titled, Estrogen receptor actions in colitis
Open the PDF for Estrogen receptor actions in colitis in another window
Articles

Mineralocorticoid receptor actions in cardiovascular development and disease

Morag J. Young, Colin D. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 901–911.
https://doi.org/10.1042/EBC20210006
Published: 26 November 2021
View article titled, Mineralocorticoid receptor actions in cardiovascular development and disease
Open the PDF for Mineralocorticoid receptor actions in cardiovascular development and disease in another window
Articles

The non-coding genome in genetic brain disorders: new targets for therapy?

Eva Medico-Salsench, Faidra Karkala, Kristina Lanko, Tahsin Stefan Barakat
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 671–683.
https://doi.org/10.1042/EBC20200121
Published: 27 October 2021
View article titled, The non-coding genome in genetic brain disorders: new targets for therapy?
Open the PDF for The non-coding genome in genetic brain disorders: new targets for therapy? in another window
Articles

3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases

Ji Young Choi, Bhushan Mahadik, John P. Fisher
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (3): 519–531.
https://doi.org/10.1042/EBC20200105
Published: 06 August 2021
View article titled, 3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases
Open the PDF for 3D printing technologies for in vitro vaccine testing platforms and vaccine delivery systems against infectious diseases in another window
Articles

Guardians of the genome: DNA damage and repair

Qian Wu
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 683–685.
https://doi.org/10.1042/EBC20200109
Published: 23 October 2020
View article titled, Guardians of the genome: DNA damage and repair
Open the PDF for Guardians of the genome: DNA damage and repair in another window
Articles

RecQ helicases in DNA repair and cancer targets

Joseph A. Newman, Opher Gileadi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 819–830.
https://doi.org/10.1042/EBC20200012
Published: 23 October 2020
View article titled, RecQ helicases in DNA repair and cancer targets
Open the PDF for RecQ helicases in DNA repair and cancer targets in another window
Articles

Alerting the immune system to DNA damage: micronuclei as mediators

Kate M. MacDonald, Soraya Benguerfi, Shane M. Harding
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 753–764.
https://doi.org/10.1042/EBC20200016
Published: 26 August 2020
View article titled, Alerting the immune system to DNA damage: micronuclei as mediators
Open the PDF for Alerting the immune system to DNA damage: micronuclei as mediators in another window
Articles

Lyso-glycosphingolipids: presence and consequences

Marco van Eijk, Maria J. Ferraz, Rolf G. Boot, Johannes M.F.G. Aerts
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 565–578.
https://doi.org/10.1042/EBC20190090
Published: 18 August 2020
View article titled, Lyso-glycosphingolipids: presence and consequences
Open the PDF for Lyso-glycosphingolipids: presence and consequences in another window
Articles

Structural insight into FANCI–FANCD2 monoubiquitination

Landing Li, Winnie Tan, Andrew J. Deans
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 807–817.
https://doi.org/10.1042/EBC20200001
Published: 29 July 2020
View article titled, Structural insight into FANCI–FANCD2 monoubiquitination
Open the PDF for Structural insight into FANCI–FANCD2 monoubiquitination in another window
Articles

Correction: The genetic basis of disease

Maria Jackson, Leah Marks, Gerhard H.W. May, Joanna B. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (4): 681.
https://doi.org/10.1042/EBC20170053_COR
Published: 28 July 2020
View article titled, Correction: The genetic basis of disease
Open the PDF for Correction: The genetic basis of disease in another window
Articles

Oxidation of polyunsaturated fatty acids to produce lipid mediators

William W. Christie, John L. Harwood
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 401–421.
https://doi.org/10.1042/EBC20190082
Published: 03 July 2020
View article titled, Oxidation of polyunsaturated fatty acids to produce lipid mediators
Open the PDF for Oxidation of polyunsaturated fatty acids to produce lipid mediators in another window
Articles

Advances and surprises in a decade of oocyte meiosis research

Binyam Mogessie
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 263–275.
https://doi.org/10.1042/EBC20190068
Published: 15 June 2020
View article titled, Advances and surprises in a decade of oocyte meiosis research
Open the PDF for Advances and surprises in a decade of oocyte meiosis research in another window
Articles

Leaving no-one behind: how CENP-E facilitates chromosome alignment

Benjamin Craske, Julie P.I. Welburn
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 313–324.
https://doi.org/10.1042/EBC20190073
Published: 29 April 2020
View article titled, Leaving no-one behind: how CENP-E facilitates chromosome alignment
Open the PDF for Leaving no-one behind: how CENP-E facilitates chromosome alignment in another window
Articles

Hypochlorous acid-mediated modification of proteins and its consequences

Clare L. Hawkins
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (1): 75–86.
https://doi.org/10.1042/EBC20190045
Published: 23 December 2019
View article titled, Hypochlorous acid-mediated modification of proteins and its consequences
Open the PDF for Hypochlorous acid-mediated modification of proteins and its consequences in another window
Articles

Modification of proteins by reactive lipid oxidation products and biochemical effects of lipoxidation

Corinne M. Spickett, Andrew R. Pitt
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (1): 19–31.
https://doi.org/10.1042/EBC20190058
Published: 23 December 2019
View article titled, Modification of proteins by reactive lipid oxidation products and biochemical effects of lipoxidation
Open the PDF for Modification of proteins by reactive lipid oxidation products and biochemical effects of lipoxidation in another window
Articles

DNA methylation at the crossroads of gene and environment interactions

Pui-Pik Law, Michelle L. Holland
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 717–726.
https://doi.org/10.1042/EBC20190031
Published: 29 November 2019
View article titled, DNA methylation at the crossroads of gene and environment interactions
Open the PDF for DNA methylation at the crossroads of gene and environment interactions in another window
Articles

DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome

Maja Vukic, Lucia Daxinger
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 773–783.
https://doi.org/10.1042/EBC20190035
Published: 14 November 2019
View article titled, DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome
Open the PDF for DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome in another window
Articles

Adhesion and growth factor receptor crosstalk mechanisms controlling cell migration

Joanna R. Thomas, Nikki R. Paul, Mark R. Morgan
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (5): 553–567.
https://doi.org/10.1042/EBC20190025
Published: 24 September 2019
View article titled, Adhesion and growth factor receptor crosstalk mechanisms controlling cell migration
Open the PDF for Adhesion and growth factor receptor crosstalk mechanisms controlling cell migration in another window
Articles

Lysyl oxidases: from enzyme activity to extracellular matrix cross-links

Sylvain D. Vallet, Sylvie Ricard-Blum
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (3): 349–364.
https://doi.org/10.1042/EBC20180050
Published: 05 September 2019
View article titled, Lysyl oxidases: from enzyme activity to extracellular matrix cross-links
Open the PDF for Lysyl oxidases: from enzyme activity to extracellular matrix cross-links in another window