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Articles

Perivascular tumor-associated macrophages and their role in cancer progression

Meriem Bahri, Joanne E. Anstee, James W. Opzoomer, James N. Arnold
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20220242.
DOI: https://doi.org/10.1042/EBC20220242
Published: 18 May 2023
View article titled, Perivascular tumor-associated macrophages and their role in cancer progression
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Articles

Immunologically relevant effects of radiation therapy on the tumor microenvironment

Claudia Galassi, Vanessa Klapp, Silvia C. Formenti, Sandra Demaria, Lorenzo Galluzzi
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20220248.
DOI: https://doi.org/10.1042/EBC20220248
Published: 18 May 2023
View article titled, Immunologically relevant effects of radiation therapy on the tumor microenvironment
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Articles

De novo priming: driver of immunotherapy responses or epiphenomenon?

Alexander L. Young, Tara Lorimer, Sarwah K. Al-Khalidi, Edward W. Roberts
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20220244.
DOI: https://doi.org/10.1042/EBC20220244
Published: 04 May 2023
View article titled, De novo priming: driver of immunotherapy responses or epiphenomenon?
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Articles

Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function

Sarah J. Backe, Mehdi Mollapour, Mark R. Woodford
Journal: Essays in Biochemistry
Essays Biochem (2023) EBC20220224.
DOI: https://doi.org/10.1042/EBC20220224
Published: 13 March 2023
View article titled, Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function
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Articles

The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer

Mayra A. Marques, Guilherme A.P. de Oliveira, Jerson L. Silva
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1023–1033.
DOI: https://doi.org/10.1042/EBC20220064
Published: 16 December 2022
View article titled, The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer
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Articles

Evo-devo perspectives on cancer

Aurora M. Nedelcu
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (6): 797–815.
DOI: https://doi.org/10.1042/EBC20220041
Published: 08 December 2022
View article titled, Evo-devo perspectives on cancer
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Articles

A special issue of Essays in Biochemistry on cancer stem cells

Fan Ying, Terence Kin Wah Lee
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 287–289.
DOI: https://doi.org/10.1042/EBC20220049
Published: 16 September 2022
View article titled, A special issue of Essays in Biochemistry on cancer stem cells
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Articles

Targeting protein kinases in cancer stem cells

Chin Ngok Chu, Terence Kin Wah Lee
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 399–412.
DOI: https://doi.org/10.1042/EBC20220002
Published: 16 September 2022
View article titled, Targeting protein kinases in cancer stem cells
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Articles

IDH mutation and cancer stem cell

Yang Zhang, Yang Liu, Fengchao Lang, Chunzhang Yang
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 413–422.
DOI: https://doi.org/10.1042/EBC20220008
Published: 16 September 2022
View article titled, IDH mutation and cancer stem cell
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Articles

Oncofetal proteins and cancer stem cells

Qian Yan, Xiaona Fang, Chenxi Li, Ping Lan, Xinyuan Guan
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 423–433.
DOI: https://doi.org/10.1042/EBC20220025
Published: 16 September 2022
View article titled, Oncofetal proteins and cancer stem cells
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Articles

CRISPR screening in cancer stem cells

Bei Wang, Alan S.L. Wong
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 305–318.
DOI: https://doi.org/10.1042/EBC20220009
Published: 16 September 2022
View article titled, CRISPR screening in cancer stem cells
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Articles

Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches

Ki-Fong Man, Stephanie Ma
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 371–386.
DOI: https://doi.org/10.1042/EBC20220001
Published: 16 September 2022
View article titled, Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches
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Articles

WNT signaling and cancer stemness

Masuko Katoh, Masaru Katoh
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 319–331.
DOI: https://doi.org/10.1042/EBC20220016
Published: 16 September 2022
View article titled, WNT signaling and cancer stemness
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Articles

Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness

Xiaozhuo Liu, Wen (Jess) Li, Igor Puzanov, David W. Goodrich, Gurkamal Chatta, Dean G. Tang
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 291–303.
DOI: https://doi.org/10.1042/EBC20220003
Published: 16 September 2022
View article titled, Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness
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Articles

Panoramic view of microRNAs in regulating cancer stem cells

Yongzhi Zhao, Danduo Wei, Yitong Zhang, Junfang Ji
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 345–358.
DOI: https://doi.org/10.1042/EBC20220007
Published: 16 September 2022
View article titled, Panoramic view of microRNAs in regulating cancer stem cells
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Articles

Lipids and the cancer stemness regulatory system in acute myeloid leukemia

Isabel N.X. Lim, Murtaza S. Nagree, Stephanie Z. Xie
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 333–344.
DOI: https://doi.org/10.1042/EBC20220028
Published: 16 September 2022
View article titled, Lipids and the cancer stemness regulatory system in acute myeloid leukemia
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Articles

Stochastic population dynamics of cancer stemness and adaptive response to therapies

Paras Jain, Atchuta Srinivas Duddu, Mohit Kumar Jolly
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 387–398.
DOI: https://doi.org/10.1042/EBC20220038
Published: 16 September 2022
View article titled, Stochastic population dynamics of cancer stemness and adaptive response to therapies
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Articles

Biomechanics of cancer stem cells

Xi Chen, Kai Tang, Xueyi Li, Cunyu Zhang, Ying Xin, Keming Li, Youhua Tan
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (4): 359–369.
DOI: https://doi.org/10.1042/EBC20220014
Published: 16 September 2022
View article titled, Biomechanics of cancer stem cells
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Articles

Uptake of formative feedback: perspective from a transnational education cohort

Sabita Menon, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 75–81.
DOI: https://doi.org/10.1042/EBC20210052
Published: 29 April 2022
View article titled, Uptake of formative feedback: perspective from a transnational education cohort
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Articles

Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts

Torben Lund, Rosemary K. Clyne
Journal: Essays in Biochemistry
Essays Biochem (2022) 66 (1): 45–51.
DOI: https://doi.org/10.1042/EBC20210053
Published: 29 April 2022
View article titled, Case Study: Implementation and evaluation of a team-based authentic research project module for large cohorts
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Articles

The physiological role of estrogen receptor functional domains

Yukitomo Arao, Kenneth S. Korach
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 867–875.
DOI: https://doi.org/10.1042/EBC20200167
Published: 26 November 2021
View article titled, The physiological role of estrogen receptor functional domains
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Articles

Progesterone receptors in normal breast development and breast cancer

Sebastian Giulianelli, Caroline A. Lamb, Claudia Lanari
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 951–969.
DOI: https://doi.org/10.1042/EBC20200163
Published: 26 November 2021
View article titled, Progesterone receptors in normal breast development and breast cancer
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Articles

Orphan nuclear receptor 4A1 (NR4A1) and novel ligands

Stephen Safe, Rupesh Shrestha, Kumaravel Mohankumar
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 877–886.
DOI: https://doi.org/10.1042/EBC20200164
Published: 26 November 2021
View article titled, Orphan nuclear receptor 4A1 (NR4A1) and novel ligands
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Articles

Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment

Carlos Perez Kerkvliet, Thu H. Truong, Julie Hanson Ostrander, Carol A. Lange
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 971–983.
DOI: https://doi.org/10.1042/EBC20200165
Published: 26 November 2021
View article titled, Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment
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Articles

Functional roles of female sex hormones and their nuclear receptors in cervical cancer

Seoung-Ae Lee, Seunghan Baik, Sang-Hyuk Chung
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 941–950.
DOI: https://doi.org/10.1042/EBC20200175
Published: 26 November 2021
View article titled, Functional roles of female sex hormones and their nuclear receptors in cervical cancer
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Articles

Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer

Corinne N. Haines, Suzanne E. Wardell, Donald P. McDonnell
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 985–1001.
DOI: https://doi.org/10.1042/EBC20200174
Published: 26 November 2021
View article titled, Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer
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Articles

Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer

Qin Tang, Ronald M. Evans
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (6): 1015–1024.
DOI: https://doi.org/10.1042/EBC20210038
Published: 26 November 2021
View article titled, Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer
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Articles

Non-coding RNA in cancer

Huiwen Yan, Pengcheng Bu
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 625–639.
DOI: https://doi.org/10.1042/EBC20200032
Published: 27 October 2021
View article titled, Non-coding RNA in cancer
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Articles

Circular RNAs as microRNA sponges: evidence and controversies

Morten T. Jarlstad Olesen, Lasse S. Kristensen
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 685–696.
DOI: https://doi.org/10.1042/EBC20200060
Published: 27 October 2021
View article titled, Circular RNAs as microRNA sponges: evidence and controversies
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Articles

Non-coding RNA dysregulation in skin cancers

Giorgio Durante, Francesca Comito, Martina Lambertini, Elisabetta Broseghini, Emi Dika, Manuela Ferracin
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (4): 641–655.
DOI: https://doi.org/10.1042/EBC20200048
Published: 27 October 2021
View article titled, Non-coding RNA dysregulation in skin cancers
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Articles

Introduction to bioprinting of in vitro cancer models

Hee-Gyeong Yi
Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (3): 603–610.
DOI: https://doi.org/10.1042/EBC20200104
Published: 06 August 2021
View article titled, Introduction to bioprinting of in vitro cancer models
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Articles

RecQ helicases in DNA repair and cancer targets

Joseph A. Newman, Opher Gileadi
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 819–830.
DOI: https://doi.org/10.1042/EBC20200012
Published: 23 October 2020
View article titled, RecQ helicases in DNA repair and cancer targets
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Articles

Kinetochore–microtubule coupling mechanisms mediated by the Ska1 complex and Cdt1

Amit Rahi, Manas Chakraborty, Kristen Vosberg, Dileep Varma
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (2): 337–347.
DOI: https://doi.org/10.1042/EBC20190075
Published: 26 August 2020
View article titled, Kinetochore–microtubule coupling mechanisms mediated by the Ska1 complex and Cdt1
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Articles

Alerting the immune system to DNA damage: micronuclei as mediators

Kate M. MacDonald, Soraya Benguerfi, Shane M. Harding
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 753–764.
DOI: https://doi.org/10.1042/EBC20200016
Published: 26 August 2020
View article titled, Alerting the immune system to DNA damage: micronuclei as mediators
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Articles

Eicosanoids

Philip C. Calder
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 423–441.
DOI: https://doi.org/10.1042/EBC20190083
Published: 18 August 2020
View article titled, Eicosanoids
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Articles

Making it or breaking it: DNA methylation and genome integrity

Anusha Sriraman, Turja K. Debnath, Blerta Xhemalce, Kyle M. Miller
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 687–703.
DOI: https://doi.org/10.1042/EBC20200009
Published: 18 August 2020
View article titled, Making it or breaking it: DNA methylation and genome integrity
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Articles

Mechanism and significance of chromosome damage repair by homologous recombination

Ajinkya S. Kawale, Patrick Sung
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 779–790.
DOI: https://doi.org/10.1042/EBC20190093
Published: 05 August 2020
View article titled, Mechanism and significance of chromosome damage repair by homologous recombination
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Articles

Correction: Base excision repair and its implications to cancer therapy

Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 845.
DOI: https://doi.org/10.1042/EBC20200013_COR
Published: 29 July 2020
View article titled, Correction: Base excision repair and its implications to cancer therapy
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Articles

Correction: The genetic basis of disease

Maria Jackson, Leah Marks, Gerhard H.W. May, Joanna B. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (4): 681.
DOI: https://doi.org/10.1042/EBC20170053_COR
Published: 28 July 2020
View article titled, Correction: The genetic basis of disease
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Articles

Repair pathway choice for double-strand breaks

Yixi Xu, Dongyi Xu
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 765–777.
DOI: https://doi.org/10.1042/EBC20200007
Published: 10 July 2020
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Articles

Base excision repair and its implications to cancer therapy

Gabrielle J. Grundy, Jason L. Parsons
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 831–843.
DOI: https://doi.org/10.1042/EBC20200013
Published: 10 July 2020
View article titled, Base excision repair and its implications to cancer therapy
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Articles

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining

Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L. Blundell, Amanda K. Chaplin
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (5): 791–806.
DOI: https://doi.org/10.1042/EBC20190092
Published: 24 June 2020
View article titled, Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
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Articles

Signalling by lysophosphatidate and its health implications

Denise G. Hemmings, David N. Brindley
Journal: Essays in Biochemistry
Essays Biochem (2020) 64 (3): 547–563.
DOI: https://doi.org/10.1042/EBC20190088
Published: 26 May 2020
View article titled, Signalling by lysophosphatidate and its health implications
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Articles

The DNA methylation landscape in cancer

Ksenia Skvortsova, Clare Stirzaker, Phillippa Taberlay
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 797–811.
DOI: https://doi.org/10.1042/EBC20190037
Published: 17 December 2019
View article titled, The DNA methylation landscape in cancer
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Articles

Textures of the tumour microenvironment

Julie S Di Martino, Chandrani Mondal, Jose Javier Bravo-Cordero
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (5): 619–629.
DOI: https://doi.org/10.1042/EBC20190019
Published: 17 October 2019
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Articles

Cell matrix adhesion in cell migration

James R.W. Conway, Guillaume Jacquemet
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (5): 535–551.
DOI: https://doi.org/10.1042/EBC20190012
Published: 23 August 2019
View article titled, Cell matrix adhesion in cell migration
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Articles

Membrane dynamics in cell migration

Montserrat Llanses Martinez, Elena Rainero
Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (5): 469–482.
DOI: https://doi.org/10.1042/EBC20190014
Published: 26 July 2019
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Articles

The biochemical basis of disease

Alastair J. Barr
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (5): 619–642.
DOI: https://doi.org/10.1042/EBC20170054
Published: 03 December 2018
View article titled, The biochemical basis of disease
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Articles

The genetic basis of disease

Maria Jackson, Leah Marks, Gerhard H.W. May, Joanna B. Wilson
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (5): 643–723.
DOI: https://doi.org/10.1042/EBC20170053
Published: 03 December 2018
View article titled, The genetic basis of disease
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Articles

Context-dependent spindle pole focusing

Lori Borgal, James G. Wakefield
Journal: Essays in Biochemistry
Essays Biochem (2018) 62 (6): 803–813.
DOI: https://doi.org/10.1042/EBC20180034
Published: 14 November 2018
View article titled, Context-dependent spindle pole focusing
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