Issues

The migration of cells is fundamental to the development and maintenance of organisms, however the complexity involved creates challenges for fully understanding the process. This issue of Essays in Biochemistry includes reviews on membrane dynamics, actin dynamics, cell matrix adhesion, microtubules and modelling of cell migration, as well as others, all illustrating the complex nature of the cell migration process. The cover is a compiled 3D image of keratin (green) and actin (red) filament distribution in a migrating keratinocyte. Image courtesy of Rudolf E Leube.