... for the transcription-translation reaction and is supplemented with additional resources for on-demand protein expression. Widely used in synthetic biology, CF extract has achieved remarkable success in the rapid detection of either biomolecules, disease pathogens or environmental pollutants due to its portability...

... unresolved across the plant kingdom. The rapid advancement of genetics and biochemical tools has enhanced our ability to identify plant specialized metabolic pathways. Further advancements in transgenic technology and synthetic biology approaches have extended this to a desire to design new pathways or move...

...Sven Epple; Afaf H. El-Sagheer; Tom Brown The modification of DNA or RNA backbones is an emerging technology for therapeutic oligonucleotides, synthetic biology and biotechnology. Despite a plethora of reported artificial backbones, their vast potential is not fully utilised. Limited synthetic...

... 10.15252/msb.20145243 3 Ranzoni , A.M. and Cvejic , A. ( 2018 ) Single-cell biology: resolving biological complexity, one cell at a time . Development 145 , dev163972 10.1242/dev.163972 4 Jia , H. and Schwille , P. ( 2019 ) Bottom-up synthetic biology...

...Adam M. Vogel; Kylie M. Persson; Travis R. Seamons; Tara L. Deans Synthetic biology is a relatively new field of science that combines aspects of biology and engineering to create novel tools for the construction of biological systems. Using tools within synthetic biology, stem cells can...

... with orthogonal components have attempted to provide tools to parse signaling and resultant phenotypes. Recent advances in synthetic biology provide opportunities to engineer receptors at scale and with additional properties that could further inform GPCR biology at a system's level, and enhance the ability...

... droplets synthetic biology synthetic cells tissues Synthetic tissues are materials designed to substitute for natural tissues and even exhibit enhanced properties. They generally comprise a 3D-patterned collection of compartments (usually picoliters in volume) that can communicate with each...

...David Tew Through the application of the engineering paradigm of ‘design–build–test–learn’ allied to recent advances in DNA sequencing, bioinformatics and, critically, the falling cost of DNA synthesis, Synthetic Biology promises to make existing therapies more accessible and be at the centre...

...Paul S. Freemont Synthetic biology is a rapidly emerging interdisciplinary research field that is primarily built upon foundational advances in molecular biology combined with engineering design. The field considers living systems as programmable at the genetic level and has been defined...

... essence; which is to interpret instructions and execute them. The sheer expanse of this question is intimidating. Gene editing, artificial intelligences, synthetic biology — these technologies present fundamental trials for the structure of society and indeed our conception of what it is to be human...

... License 4.0 (CC BY-NC-ND) . biotechnology enzymology industrial biocatalysis microfluidics protein engineering synthetic biology Nature is an incredible chemist. Photosynthesis uses the energy of light to convert inorganic carbon into the central building blocks of life...

... in the hydrogel nucleus. It should be noted that although not discussed here, chemical communication between nanoparticles has also been demonstrated [ 32 , 33 ]. artificial cell biotechnology synthetic biology synthetic cells Although several enzymes and metabolic pathways have been reconstituted...