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Keywords: vasculature
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Clin Sci (Lond) (2020) 134 (22): 3023–3046.
Published: 24 November 2020
... Vasculature The first epidemiological studies by Barker and Osmond [ 3 , 4 , 5 ] laid the foundations for the fetal origins of disease, which established links between undernutrition during fetal life (and to a lesser extent in infancy and early childhood) and patterns of chronic disease in later life...
Clin Sci (Lond) (2020) 134 (13): 1763–1774.
Published: 10 July 2020
... Society 2020 Ctcf homeostasis hypertension nephrology renin-angiotensin system vasculature Renin-expressing cells are fundamental for the maintenance of extracellular fluid volume, and blood pressure homeostasis. Through evolution, these cells have acquired additional roles in kidney...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (20): 2503–2524.
Published: 13 October 2017
.... Here we consider the potential pathogenic role of tissue hypoxia in lesion development, arising partly from the vascular anatomy of the affected white matter. Specifically, these regions are supplied by a sparse vasculature fed by long, narrow end arteries/arterioles that are vulnerable to oxygen...
Clin Sci (Lond) (2010) 119 (9): 361–372.
Published: 23 July 2010
... compilation © 2010 Biochemical Society 2010 calcium signalling endothelin G-protein-coupled receptor ion channel vasculature ET (endothelin)-1 is a 21-amino-acid peptide, originally characterized as an endothelium-derived constricting factor in the vasculature [ 1 , 2 ]. ET-1 also affects...
Clin Sci (Lond) (2009) 116 (3): 175–190.
Published: 08 January 2009
... that may play a pivotal role in driving the atherosclerotic process in conduit vessels. Furthermore, the vast surface area of the endothelium compared with conduit vessels means that the vascular effects of endothelial dysfunction or activation will be most apparent in this section of the vasculature...
Clin Sci (Lond) (2006) 111 (1): 35–46.
Published: 14 June 2006
... existing cardiac myocytes. This process is intimately linked to the development of coronary vasculature from progenitors originating in the endothelium, the proepicardial organ and neural crest. In this review, we systematically evaluate approx. 90 mouse mutations that impair heart muscle growth during...
Clin Sci (Lond) (2003) 105 (6): 699–707.
Published: 01 December 2003
... 2003 The Biochemical Society 2003 aging circulatory physiology endothelial function heart failure inflammation thrombosis vasculature Clinical Science (2003) 105, 699 707 (Printed in Great Britain) 699 Cutaneous vascular reactivity is reduced in aging and in heart failure: association...
Clin Sci (Lond) (2001) 100 (5): 509–516.
Published: 03 April 2001
.... Correspondence : Dr A. J. Mackay (e-mail alisonjmackay@hotmail.com ). 19 9 2000 14 12 2000 26 1 2001 The Biochemical Society and the Medical Research Society © 2001 2001 vasculature pathophysiology ultrasound atherosclerosis hypertension radial artery hypertrophy...
Clin Sci (Lond) (1995) 89 (2): 177–182.
Published: 01 August 1995
... blocker (pentolinium) in conscious spontaneously hypertensive and Wistar Kyoto rats aged 20–28 weeks. To estimate the ‘amplifier property’ of hypertrophied vasculature in spontaneously hypertensive rats, which is known to modulate pressor responses, the lower blood pressure plateau after serial injections...
Clin Sci (Lond) (1994) 86 (4): 359–374.
Published: 01 April 1994
...Nicholas P. Curzen; Mark J. D. Griffiths; Timothy W. Evans © 1994 The Biochemical Society and the Medical Research Society 1994 endothelin endothelium nitric oxide sepsis vasculature Clinical Science (1994) 86, 359-374 (Printed in Great Britain) Editorial Review 359 Role...
Clin Sci (Lond) (1992) 82 (2): 163–168.
Published: 01 February 1992
... supersensitivity to catecholamines in diabetic autonomic neuropathy is Key words: a-adrenoceptors, catecholamine sensitivity, diabetic autonomic neuropathy, hand vein compliance technique, noradrenaline, phenylephrine, sympathetic nervous system, vasculature. Abbreviations: Em,, maximal response; ED,, dose...