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Keywords: urinary bladder
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Articles

Reduction of endothelin-1 binding and inhibition of endothelin-1-mediated detrusor contraction by naftidrofuryl

Robert C. CALVERT, Faiz H. MUMTAZ, Mick R. DASHWOOD, Masood A. KHAN, Robert J. MORGAN, Dimitri P. MIKHAILIDIS, Cecil S. THOMPSON
Journal: Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 459S–463S.
https://doi.org/10.1042/CS103S459S
Published: 01 September 2002
...Robert C. CALVERT; Faiz H. MUMTAZ; Mick R. DASHWOOD; Masood A. KHAN; Robert J. MORGAN; Dimitri P. MIKHAILIDIS; Cecil S. THOMPSON Endothelin-1 (ET-1) causes urinary bladder smooth muscle contraction and the endothelin receptors A and B (ET A and ET B ) are both known to be present in the rabbit...
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Articles

Pharmacological and molecular biological evidence for ETA endothelin receptor subtype mediating mechanical responses in the detrusor smooth muscle of the human urinary bladder

Takako OKAMOTO-KOIZUMI, Masayuki TAKEDA, Takeshi KOMEYAMA, Akihiko HATANO, Makoto TAMAKI, Takaki MIZUSAWA, Toshiki TSUTSUI, Kenji OBARA, Yoshihiko TOMITA, Kei ARAI, Kota TAKAHASHI
Journal: Clinical Science
Clin Sci (Lond) (1999) 96 (4): 397–402.
https://doi.org/10.1042/cs0960397
Published: 01 April 1999
... concentration-dependent contractions in human urinary bladder with a plateau at concentrations above 3×10 -7 M. Neither IRL1620 nor sarafotoxin S6c (both ET B -selective agonists; 10 -10 M to 10 -6 M) elicited contractile activity in the human urinary bladder detrusor smooth muscle. FR139317 (an ET A -selective...
View article titled, Pharmacological and molecular biological evidence for ETA endothelin receptor subtype mediating mechanical responses in the detrusor smooth muscle of the human <span class="search-highlight">urinary</span> <span class="search-highlight">bladder</span>
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Articles

Effect of Treatment with Calcium Antagonists in Vitro and in Vivo on the Contractile Response of Isolated Rat and Human Detrusor Muscle

Ruth A. Elliott, Robert I. Norman, Stuart G. Parker, R. Paul Whitaker, C. Mark Castleden
Journal: Clinical Science
Clin Sci (Lond) (1996) 91 (4): 467–474.
https://doi.org/10.1042/cs0910467
Published: 01 October 1996
... inhibitory effect on the contractile response of urinary bladder muscle [l-31. Dihydropyridine receptors at relatively low density are found in human detrusor muscle [4]. Animal experiments in vivo also suggest that cal- cium antagonists reduce the contractility of detru- sor muscle. A single intravenous...
View article titled, Effect of Treatment with Calcium Antagonists in Vitro and in Vivo on the Contractile Response of Isolated Rat and Human Detrusor Muscle
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Articles

Renin and Aldosterone Release during Sympathetic Stimulation in Tetraplegia

C. J. Mathias, H. L. Frankel, I. B. Davies, V. H. T. James, W. S. Peart
Journal: Clinical Science
Clin Sci (Lond) (1981) 60 (4): 399–404.
https://doi.org/10.1042/cs0600399
Published: 01 April 1981
...C. J. Mathias; H. L. Frankel; I. B. Davies; V. H. T. James; W. S. Peart 1. The effect of endogenous sympathetic stimulation (induced by urinary bladder stimulation) and intravenous infusion of noradrenaline and isoprenaline on blood pressure, heart rate and levels of plasma renin activity...
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