... investigated whether a nephron deficit, induced by fetal uninephrectomy at 100 days gestation (term=150 days), resulted in (i) altered renal sodium handling both under basal conditions and in response to an acute 0.9% saline load (50 ml·kg −1 of body weight·30 min −1 ); (ii) hypertension and (iii) altered...

... transplantation/uninephrectomy. At day 54, 13 donors and 11 recipients were re-investigated. Sixteen of these constituted eight matched pairs. This reduction in the study population was caused by the application of two withdrawal criteria. 2. In the recipients glomerular filtration rate was unchanged at day 5...

... synthesis. indomethacin; lithium clearance renal haemodynamics uninephrectomy urinary prostaglandin E 2 Clinical Science (1994) 86, 715-721 (Printed i n Great Britain) 715 Identical effects of indomethacin on renal function in healthy uninephrectomized subjects and in healthy control subjects C. B...

...Philip G. Baer; Alberto Nasjletti 1. Male Wistar rats were used to examine whether renal prostaglandins (PG) contribute to functional compensatory changes in the remaining kidney after uninephrectomy. Total urinary excretion of PGE 2 , PGF 2α and 6-keto-PGF 1α , a metabolite of PGI 2 , was measured...

... are unaffected by unilateral nephrectomy and suggest that, in the remaining kidney, atrate reabsorption along the entire nephron increases in proportion to the increment in glomerular filtration. Key words : concentration, dilution, kidney function, sodium reabsorption, uninephrectomy. Correspondence: Dr Adrian...