... importantly, they provide novel avenues to improve wound healing process such as diabetic foot ulcers (DFUs) by targeting NETs. © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 Diabetes Interleukin 1b NETosis Neutrophil Ulcer...

...J. S. Mohan; J. M. Marshall; H. L. Reid; P. W. Thomas; G. R. Serjeant 1. Chronic leg ulceration is a major cause of morbidity in patients with homozygous sickle cell disease; the ulcers commonly resolve on bed rest. We have therefore compared the cutaneous vascular response to dependency in three...

... gastric ulcer, prostaglandin (E+A)-like material reached concentrations four times higher than in normal subjects, accompanied by a fivefold increase of prostaglandin F-like substances. After healing of the gastric ulcer, prostaglandins returned to normal values. 3. There was no correlation between...