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Keywords: treatment
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Clin Sci (Lond) (2018) 132 (13): 1403–1415.
Published: 09 July 2018
... the progression of renal fibrosis in a mouse model of unilateral ureteral obstructive nephropathy (UUO). We found that preventive treatment with SIS3 at the time of disease induction largely suppressed progressive renal fibrosis by inhibiting α-smooth muscle actin (α-SMA) + myofibroblast accumulation...
Clin Sci (Lond) (2006) 110 (3): 267–278.
Published: 10 February 2006
... to illuminate the in vivo pathophysiological significance of this protein. Although evaluation of adiponectin as a novel therapy will ultimately require clinical intervention studies, this mediator may represent a novel target for the prevention and treatment of visceral obesity metabolic syndrome...
Clin Sci (Lond) (2006) 110 (1): 73–88.
Published: 12 December 2005
...Olivia J. Handley; Jenny J. Naji; Stephen B. Dunnett; Anne E. Rosser HD (Huntington's disease) is a devastating neurodegenerative disorder caused by a polyglutamine expansion in the gene encoding the huntingtin protein. Presently, there is no known cure for HD and existing symptomatic treatments...
Clin Sci (Lond) (2005) 108 (1): 23–36.
Published: 15 December 2004
... to overt HF. The BNP peptides also predict subsequent haemodynamic deterioration and adverse events in cardiovascular disease, and can therefore be used to monitor those at high risk and act as a guide to optimization of treatment. The favourable biological properties of the natriuretic peptides have also...
Clin Sci (Lond) (2004) 107 (6): 539–557.
Published: 24 November 2004
... failure. Although a range of diagnostic methods may help to characterize alterations in cardiac function in general, none are specific for the alterations in diabetes. Treatment paradigms are very much limited to interpretation and translation from the results of interventions in non-diabetic patients...
Clin Sci Mol Med (1976) 51 (s3): 657s–659s.
Published: 01 December 1976
...C. Hodes; P. A. Rogers; M. G. Everitt 1. A screening programme has been set up in a group general practice for identifying and treating moderate high blood pressure in men and women aged 45–54 years, and at the same time the identification and treatment of high blood pressure in patients...