.... bone marrow macrophages inflammation innate immunity non alcoholic fatty liver disease necroptosis Toll-like receptors Among patients with non-alcoholic fatty liver disease (NAFLD), adverse liver outcomes are confined to those (10–25%) with steatohepatitis (non-alcoholic steatohepatitis...

... glomerulonephritis inflammation lupus nephritis toll-like receptors Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease characterized by a polyclonal autoimmune response against numerous nuclear autoantigens. Hence, the hallmark of SLE is the persistent presence of antinuclear...

.../R) prior to the development of cTnI antibody. In vitro work shows that cTnI can induce increases in vascular cell adhesion molecule 1 (VCAM-1) expression and cell adhesion, with toll-like receptor 4 (TLR4) and nuclear factor kappa beta (NF-κB) involved in the downstream signalling. 30 6 2016...

... that detection of extracellular RNA by the Toll-like receptors (TLRs) 3 and 7 is a key initiating signal that contributes to the development of pre-eclampsia. PLacental eXpanded (PLX-PAD) cells are human placenta-derived, mesenchymal-like, adherent stromal cells that have anti-inflammatory, proangiogenic...

... contribute to adverse ventricular remodelling. Such inflammation is initiated by molecular danger signals released by damaged myocardium, which induce innate immune responses by activating toll-like receptors (TLRs). Detrimental roles have been recently reported for TLR2, TLR3 and TLR4. The role of other...