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Keywords: toll-like receptors
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Clin Sci (Lond) (2017) 131 (16): 2145–2159.
Published: 24 July 2017
... innate immunity non alcoholic fatty liver disease necroptosis Toll-like receptors Among patients with non-alcoholic fatty liver disease (NAFLD), adverse liver outcomes are confined to those (10–25%) with steatohepatitis (non-alcoholic steatohepatitis, NASH) [ 1 ]. The essential difference...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (8): 625–634.
Published: 28 March 2017
... Press Limited on behalf of the Biochemical Society 2017 autoimmunity glomerulonephritis inflammation lupus nephritis toll-like receptors Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease characterized by a polyclonal autoimmune response against numerous...
Clin Sci (Lond) (2016) 130 (24): 2277–2278.
Published: 10 November 2016
.../R) prior to the development of cTnI antibody. In vitro work shows that cTnI can induce increases in vascular cell adhesion molecule 1 (VCAM-1) expression and cell adhesion, with toll-like receptor 4 (TLR4) and nuclear factor kappa beta (NF-κB) involved in the downstream signalling...
Clin Sci (Lond) (2016) 130 (7): 513–523.
Published: 17 February 2016
... that detection of extracellular RNA by the Toll-like receptors (TLRs) 3 and 7 is a key initiating signal that contributes to the development of pre-eclampsia. PLacental eXpanded (PLX-PAD) cells are human placenta-derived, mesenchymal-like, adherent stromal cells that have anti-inflammatory, proangiogenic...
Includes: Supplementary data
Clin Sci (Lond) (2015) 129 (2): 187–198.
Published: 30 April 2015
... contribute to adverse ventricular remodelling. Such inflammation is initiated by molecular danger signals released by damaged myocardium, which induce innate immune responses by activating toll-like receptors (TLRs). Detrimental roles have been recently reported for TLR2, TLR3 and TLR4. The role of other...