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Keywords: therapy
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Clin Sci (Lond) (2020) 134 (20): 2741–2754.
Published: 28 October 2020
... 2020 biomarker extracellular vesicles glomerular diseases mechanism therapy Extracellular vesicles (EVs), including exosomes, microvesicles and apoptotic bodies [ 1 ], are membrane-bound nanoparticles released by most cells and can be detected in diverse biological fluids [ 2 ]. First...
Clin Sci (Lond) (2017) 131 (20): 2503–2524.
Published: 13 October 2017
... of the Biochemical Society 2017 demyelination hypoxia oligodendrocytes therapy vasculature watershed The periventricular and deep white matter is preferentially affected in a range of neurological disorders, notably small vessel disease (SVD) and multiple sclerosis (MS), but also including some...
Clin Sci (Lond) (2016) 130 (8): 565–574.
Published: 08 March 2016
... of dysfunction within these systems. We then examine the evidence for a role for copper in pathogenic processes in Parkinson's disease and consider reports of diverse copper-modulating strategies in in vitro and in vivo models of this disorder. Copper-modulating therapies are currently advancing through clinical...
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... diagnosis hypertension kidney microRNA (miRNA) therapy translational research miRNAs (microRNAs) are endogenously produced non-coding RNA molecules approximately 22 nucleotides long that play a ubiquitous and important role in regulating protein expression ( Figure 1 A). miRNAs, and non-coding...
Clin Sci (Lond) (2010) 118 (11): 641–655.
Published: 09 March 2010
... compilation © 2010 Biochemical Society 2010 apolipoprotein E (ApoE) atherosclerosis cardiovascular disease chemokine macrophage therapy Atherosclerosis is the underlying cause of cardiovascular diseases including heart attack and stroke. The pathology of these diseases is characterized...
Includes: Multimedia, Supplementary data
Clin Sci (Lond) (2005) 109 (1): 13–25.
Published: 23 June 2005
... therapy CML is a myeloproliferative disorder consequent to the acquisition of a characteristic genetic rearrangement, the Philadelphia chromosome (t9:22), by a haemopoietic stem cell. The translocation brings two genes into juxtaposition, BCR (breakpoint cluster region) on chromosome 22 and the c...
Clin Sci (Lond) (1995) 89 (6): 633–636.
Published: 01 December 1995
... patients with migraine headaches who may respond to an intravenous infusion of MgSO 4 . 10 8 1995 22 8 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 migraine therapy ionized magnesium magnesium sulphate Clinical Science (1995) 89, 633-636 (Printed...