...Veronica Begni; Marco Andrea Riva; Annamaria Cattaneo Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection. The BDNF gene structure is very complex and consists of multiple 5...

... synaptic plasticity Neurotrophins are an essential family of secreted proteins for neuronal development. Nerve growth factor (NGF) was discovered more than 60 years ago, and it was found to be necessary for the survival and development of the peripheral nervous system [ 1 – 3 ]. Early studies...

...Hongmei Shen; Zheng Li The identification and functional delineation of miRNAs (a class of small non-coding RNAs) have added a new layer of complexity to our understanding of the molecular mechanisms underlying synaptic plasticity. Genome-wide association studies in conjunction with investigations...