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Keywords: synaptic plasticityClose
Clin Sci (Lond) (2017) 131 (2): 123–138.
Published: 23 December 2016
...Veronica Begni; Marco Andrea Riva; Annamaria Cattaneo Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection. The BDNF gene structure is very complex and consists of multiple 5...
Clin Sci (Lond) (2017) 131 (1): 13–23.
Published: 01 December 2016
... and review recent clinical strategies for restoring BDNF signalling in disease. activity-dependent expression deep brain stimulation neuroprotection neurotrophin signalling synaptic plasticity A link to Alzheimer disease (AD) was made in the 1980s based on studies on aged animals in which...
Clin Sci (Lond) (2016) 130 (14): 1137–1146.
Published: 01 June 2016
...Hongmei Shen; Zheng Li The identification and functional delineation of miRNAs (a class of small non-coding RNAs) have added a new layer of complexity to our understanding of the molecular mechanisms underlying synaptic plasticity. Genome-wide association studies in conjunction with investigations...