...Weronika Karle; Samuel Becker; Philipp Stenzel; Christoph Knosalla; Günter Siegel; Oliver Baum; Andreas Zakrzewicz; Janine Berkholz Promyelocytic leukemia protein (PML) is a constitutive component of PML nuclear bodies (PML-NBs), which function as stress-regulated SUMOylation factories. Since PML...

... reversed by a family of SUMO-specific proteases (SENPs), making SUMOylation an ideal regulatory mechanism for developing novel therapeutic strategies for promoting a cardiac regenerative response. However, the role of SUMOylation in cardiac regeneration remains unknown. In the present study, we assessed...