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Keywords: stable isotope
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Articles
Clin Sci (Lond) (2015) 129 (4): 375–384.
Published: 27 May 2015
... by Portland Press Limited 2015 We examined the usefulness of a three-compartment model for description of lactate kinetics using stable isotopically labelled lactate in humans. The main results showed that adrenaline increased lactate release from, and mitochondrial ex vivo respiration in, human...
Articles
Clin Sci (Lond) (2015) 128 (1): 57–67.
Published: 29 August 2014
... in this short-term (8 h) dose–response study. L -Arginine-HCl was continuously infused [intravenously (IV)] in three stepwise-increasing doses (33, 66 and 99 μmol·kg −1 ·h −1 ). Whole-body arginine-NO and protein metabolism were measured using stable isotope techniques, and baseline values were compared...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2008) 114 (4): 339–346.
Published: 15 January 2008
... synthesis in muscle and liver. Correspondence: Dr Giuseppe Caso (email Giuseppe.Caso@stonybrook.edu ). albumin cardiopulmonary bypass coronary artery bypass graft (CABG) fibrinogen muscle protein synthesis stable isotope Surgical trauma is accompanied by accelerated protein...
Articles
Clin Sci (Lond) (2007) 112 (10): 527–532.
Published: 12 April 2007
... with an attenuated acute-phase response. This indicates that altered arginine metabolism may be an important characteristic of the metabolic changes in cancer. amino acid arginine cancer metabolism nitric oxide stable isotope surgery We have described recently [ 1 ] that patients with malignant...
Articles
Clin Sci (Lond) (2006) 110 (1): 93–99.
Published: 12 December 2005
... reaction undergoing laparoscopic cholecystectomy. Correspondence: Dr Hans Barle (email hans.barle@ds.se ). cholecystitis inflammation liver protein MS stable isotope synthesis rate Catabolic states are characterized by specific changes in protein metabolism. As the liver plays...
Articles
Clin Sci (Lond) (2005) 109 (6): 513–521.
Published: 23 November 2005
... sensitivity intravenous glucose tolerance test (IVGTT) minimal model stable isotope Correspondence: Dr Leslie J. C. Bluck (email les.bluck@mrc-hnr.cam.ac.uk ). Modelling was performed using a spreadsheet (Excel 2000, version 9.0.2720; Microsoft) with fitting of model parameters...
Articles
Clin Sci (Lond) (2004) 107 (6): 601–607.
Published: 24 November 2004
... Inga Tjäder (email inga.tjader@ltkronoberg.se ). 2 7 2004 19 8 2004 24 8 2004 24 8 2004 The Biochemical Society 2004 protein synthesis skeletal muscle stable isotope surgical trauma Muscle protein catabolism is a considerable clinical problem following...
Articles
Clin Sci (Lond) (2002) 102 (2): 233–240.
Published: 14 January 2002
... stable isotope label. Ten volunteers (nine female, one male) aged 24-55 years were recruited from the Norwich area to take part in a free-living study. The study was conducted in the Human Nutrition Unit at the Institute of Food Research, Norwich, U.K., and involved feeding breakfast test meals...
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Clin Sci (Lond) (1996) 91 (1): 99–106.
Published: 01 July 1996
..., it is difficult to interpret these in vitro findings. Therefore, an in vivo technique has been established for determination of the fractional protein synthesis rate, as an index of metabolic activity in human peripheral blood lymphocytes, by using a stable isotope technique. 2. The rate of protein synthesis...
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Clin Sci (Lond) (1993) 84 (1): 113–117.
Published: 01 January 1993
... : control subjects, 0.018 ± 0.002 min −1 , alcoholic patients, 0.031 ± 0.006 min −1 ). 5. These data therefore demonstrate that kinetic studies using stable isotopes of Zn can provide novel information on exchangeable Zn pools in man, but provide no support for the possibility of an underlying Zn depletion...
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Clin Sci (Lond) (1991) 81 (2): 161–168.
Published: 01 August 1991
... intravascular albumin mass pregnancy stable isotope whole-body protein turnover ClinicalScience (1991) 81,161-168 161 Albumin metabolism in fasted subjects during late pregnancy 0. SAMSON OLUFEMI*, PAUL G. WHITTAKER, DAVE HALLIDAYT AND TOM LIND University Department of Obstetrics and Gynaecology, Princess...
Articles
Clin Sci (Lond) (1982) 62 (5): 553–556.
Published: 01 May 1982
... with stable isotopes, [ 15 N 2 ]urea, [6- 2 H]glucose and [3- 13 C]alanine, was used. 3. The rate of appearance of glucose and urea in the plasma was rapidly reduced by the 17.7 μUmol min −1 kg −1 glucose infusion. 4. In contrast, during the glucose infusion there was an increased rate of appearance...