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Ellen E. Gillis, Kasey Belanger, Mahmoud Abdelbary, Riyaz Mohamed, Jingping Sun, Michael W. Brands, Jennifer C. Sullivan
Clin Sci (Lond) (2021) 135 (19): 2329–2339.
Published: 13 October 2021
... the hypothesis that the greater relative abundance of renal Tregs in female SHR is due to greater Treg production. To test this hypothesis, T cell profiles were measured in the spleen by flow cytometry in male and female SHR at 5 and 14 weeks of age. Splenic Tregs did not differ between males and females...
Xiao-Ming Gao, Xiao-Lei Moore, Yang Liu, Xin-Yu Wang, Li-Ping Han, Yidan Su, Alan Tsai, Qi Xu, Ming Zhang, Gavin W. Lambert, Helen Kiriazis, Wei Gao, Anthony M. Dart, Xiao-Jun Du
Clin Sci (Lond) (2016) 130 (13): 1089–1104.
Published: 23 May 2016
... for this is unclear. Large platelets are hyperactive and associated with adverse clinical outcomes. We determined mean platelet volume (MPV) and platelet–monocyte conjugation (PMC) using blood samples from patients, and blood and the spleen from mice with AMI. We further measured changes in platelet size, PMC...
Clin Sci (Lond) (1999) 97 (1): 85–89.
Published: 01 June 1999
... with changes in granulocyte kinetics with respect to the liver, spleen and lungs. Anti-TNFα resulted in a decrease in the size of the whole-body pool of marginating granulocytes, as reflected by a significant increase in the 30 min intravascular recovery of labelled granulocytes from 40% (S.D. 10) to 47% (S.D...
H. Terence Cook, Alison J. Bune, Albertine S. Jansen, G. Michael Taylor, Rashpal K. Loi, Victoria Cattell
Clin Sci (Lond) (1994) 87 (2): 179–186.
Published: 01 August 1994
... induction was monocytes and macrophages in multiple organs, principally liver and spleen. Bronchial, bile duct, intestinal and bladder epithelium and some hepatocytes also expressed inducible NO synthase. Expression peaked at 5 h and had returned to normal by 12 h except in spleen. 3. After priming with C...
Clin Sci (Lond) (1993) 84 (6): 605–609.
Published: 01 June 1993
...% of the administered dose had accumulated in the spleen by a filtration mechanism, as compared with 5% for uncoated microspheres, at 3 h after administration. The enhanced splenic sequestration of microspheres was accompanied by a decrease in the liver uptake. In contrast, smaller poloxamine-908-coated microspheres...
Clin Sci (Lond) (1992) 83 (5): 607–614.
Published: 01 November 1992
... area is less well characterized. We were specifically interested in substrate flux across the spleen as it is an organ with important immunological functions. 2. Therefore, hindquarter, gut, spleen and liver fluxes of amino acids, ammonia, glucose, lactate and blood gases were measured for 4 days after...
P. Allsop, A. M. Peters, R. N. Arnot, A. W. J. Stuttle, M. Deenmamode, M. E. Gwilliam, M. J. Myers, G. M. Hall
Clin Sci (Lond) (1992) 83 (1): 47–54.
Published: 01 July 1992
... granulocytes (four studies) were monitored with a γ-camera immediately after injection and before and after maximal exercise performed 60 min after injection. 3. Labelled erythrocytes equilibrated rapidly between the spleen and circulating blood after injection, whereas labelled platelets and granulocytes...
Clin Sci (Lond) (1990) 78 (5): 469–474.
Published: 01 May 1990
...B. M. Fisher; G. Gillen; D. A. Hepburn; H. J. Dargie; E. Barnett; B. M. Frier 1. The effects of acute hypoglycaemia on the spleen were examined in normal humans using radioisotopic techniques, complemented by ultrasonic examination of the spleen. Hypoglycaemia had a modest effect on splenic area...
A. M. Peters, M. J. Walport, K. B. Elkon, H. J. Reavy, P. P. Ferjencik, J. P. Lavender, G. R. V. Hughes
Clin Sci (Lond) (1984) 66 (1): 55–62.
Published: 01 January 1984
... in the spleen. HD-RBC were predominantly taken up by the spleen, although slight 111 In activity was visible in the liver. 3. The blood clearance of IgG-RBC was mono-exponential, whereas that of HD-RBC was bi-exponential. The reciprocal of the t 1/2 (the time taken for the 3 min value to fall by 50%) of the HD...
Clin Sci (Lond) (1983) 65 (3): 297–302.
Published: 01 September 1983
...M. A. Zago; C. Bottura 1. Studies of splenic function were carried out on patients with sickle-cell diseases by the measurement of the clearance of autologous heat-damaged 99m Tc-labelled erythrocytes from circulation and into the spleen, the spleen area by a scintillation scanning, the enumeration...
Clin Sci (Lond) (1982) 62 (2): 169–176.
Published: 01 February 1982
... Society 1982 angiotensin captopril haemorrhage kidney meclofenamate prostaglandins spleen Clinical Science(l982) 62,169-176 169 Effects of meclofenamate and captopril on renal and other regional vascular beds after mild haemorrhage in conscious rabbits R. A. BANKS*, L. J . BEILIN, J. SOLTYS...
Clin Sci (Lond) (1981) 60 (1): 109–113.
Published: 01 January 1981
... in coeliac patients may be related to the duration of untreated disease. 30 4 1980 30 7 1980 © 1981 The Biochemical Society and the Medical Research Society 1981 coeliac disease spleen Clinical Science (1981) 60, 109-113 109 Simple method of assessing splenic function in coeliac...
Clin Sci Mol Med (1977) 53 (1): 17–25.
Published: 01 July 1977
... significantly. 5. This circulatory stimulation, after regional 2,4-dinitrophenol infusion, was abolished or was prevented from occurring by splenectomy. 6. It appears that the normal cardiac output response to tissue hypermetabolism requires both an intact spleen and normally functioning β-adrenoreceptors...