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Keywords: smoking
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Clin Sci (Lond) (2022) 136 (18): 1371–1387.
Published: 26 September 2022
...Hagit Shapiro; Kim Goldenberg; Karina Ratiner; Eran Elinav Smoking is associated with an increased risk of cancer, pulmonary and cardiovascular diseases, but the precise mechanisms by which such risk is mediated remain poorly understood. Additionally, smoking can impact the oral, nasal...
Clin Sci (Lond) (2014) 126 (4): 253–265.
Published: 14 October 2013
... cigarette smoke, causes progressive airflow limitation. This inflammation, where macrophages, neutrophils and T-cells are prominent, leads to oxidative stress, emphysema, small airways fibrosis and mucus hypersecretion. The mechanisms and mediators that drive the induction and progression of chronic...
Clin Sci (Lond) (2010) 118 (9): 565–572.
Published: 09 February 2010
...Nicholas S. Hopkinson; Michael I. Polkey COPD (chronic obstructive pulmonary disease) is the most common pulmonary disease and is the only common cause of death in which mortality is presently rising. It is caused by the inhalation of smoke, which leads to oxidative stress and inflammation both...
Clin Sci (Lond) (2007) 113 (5): 233–241.
Published: 01 August 2007
... of the population. Smoking is a key lifestyle risk factor for bone loss and fractures that appears to be independent of other risk factors for fracture such as age, weight, sex and menopausal status. This review discusses the effects of smoking on bone health in pre-menopausal and post-menopausal women and men...
Clin Sci (Lond) (2006) 111 (1): 87–91.
Published: 14 June 2006
...-smoking group (2.2±0.5 and 4.5±0.8% respectively; P <0.05). In the smoking group, FMD increased significantly ( P <0.05) to 4.0±0.8% during treatment with atorvastatin and returned to basal levels during placebo (2.3±0.6%). In the non-smoking group, FMD was unaffected by both atorvastatin...
Clin Sci (Lond) (2003) 104 (3): 247–252.
Published: 12 February 2003
...Richard G. IJZERMAN; Erik H. SERNE; Mirjam M. van WEISSENBRUCH; Renate T. de JONGH; Coen D.A. STEHOUWER An effect on microvascular function has been proposed as a possible mechanism explaining the association of acute smoking with increased blood pressure and decreased insulin sensitivity. However...
Clin Sci (Lond) (2001) 101 (1): 53–58.
Published: 24 May 2001
...Robert BUTLER; Andrew D. MORRIS; Allan D. STRUTHERS Cigarette smoking is a pernicious risk factor for the pathogenesis of coronary artery disease, and endothelial dysfunction is an important antecedent event in this process. This is important, as cigarette smoke is directly toxic to endothelial...
Clin Sci (Lond) (2001) 100 (6): 661–665.
Published: 14 May 2001
...Katherine M. ENGLISH; Peter J. PUGH; Helen PARRY; Nanette E. SCUTT; Kevin S. CHANNER; T. Hugh JONES The effect of smoking on androgen levels is important given the recent interest in the link between low levels of androgens and the development of cardiovascular disease. Numerous studies examining...
Clin Sci (Lond) (2000) 99 (1): 65–75.
Published: 15 June 2000
... decompression illness contrast echocardiography decompression sickness gas embolism lung function tests patent foramen ovale pulmonary arteriovenous fistula pulmonary barotrauma smoking spinal decompression illness 65Clinical Science (2000) 99, 65 75 (Printed in Great Britain) Relationship between...
Clin Sci (Lond) (1995) 89 (4): 333–342.
Published: 01 October 1995
...Dilys J. Freeman; Chris J. Packard coronary heart disease lipoprotein metabolism smoking triacylgycerol Clinical Science (1995) 89, 333--342 (Printed in Great Britain) Editorial Review Smoking and plasma lipoprotein metabolism Dilys J. FREEMAN* and Chris J. PACKARD *Center for Human...
Clin Sci (Lond) (1993) 85 (1): 51–55.
Published: 01 July 1993
...Marie-Cécile Jacobs; Jacques W. M. Lenders; Jan A. Kapma; Paul Smits; Theo Thien 1. Cigarette smoking is one of the major risk factors for the development of atherosclerosis. It is not clear, however, whether chronic cigarette smoking impairs the normal physiological function of the endothelium...
Clin Sci (Lond) (1989) 76 (5): 487–494.
Published: 01 May 1989
...-asthmatic men who were never-smokers (aged 26-61 years) and in 41 male cigarette smokers (aged 32-64 years). The results were compared with those for spirometry and the single-breath N 2 test which are the most commonly used techniques in epidemiological surveys for detecting the effects of smoking...
Clin Sci (Lond) (1988) 75 (4): 371–373.
Published: 01 October 1988
...Andrew J. T. Kirkham; Andrew R. Guyatt; Gordon Cumming 1. The rise (‘boost’) in carboxyhaemoglobin (HbCO) on smoking has been studied with alveolar carbon monoxide measurements before and after smoking a cigarette. We re-examined this in 28 subjects with HbCO values compared with rebreathing carbon...
Clin Sci (Lond) (1988) 74 (1): 29–36.
Published: 01 January 1988
...Andrew R. Guyatt; Andrew J. T. Kirkham; Derek C. Mariner; Gordon Cumming 1. We measured alveolar carbon monoxide (CO) after a 20 s breath-holding period and carboxyhaemoglobin both before and after smoking a cigarette on 500 occasions (101 individuals). The two measurements were closely correlated...
Clin Sci (Lond) (1985) 68 (4): 395–399.
Published: 01 April 1985
... mothers than in group I, irrespective of smoking habits. There were no racial differences in peripheral white cell zinc levels. 4. PMN, and to a lesser degree MN, zinc levels were lower in smoking than in non-smoking mothers. 5. Erythrocyte zinc did not correlate with other zinc measurements nor...
Clin Sci (Lond) (1983) 65 (6): 669–672.
Published: 01 December 1983
...-smokers there was a rise in the HDL 2 /HDL 3 cholesterol ratio after oral fat, but not in smokers. 4. These findings are compatible with the hypothesis that smoking interferes with the lipolysis of triglyceride rich lipoproteins and the conversion of HDL 3 into HDL 2 . 19 5 1983 18 7 1983...
Clin Sci (Lond) (1983) 64 (3): 273–280.
Published: 01 March 1983
... in the pathogenesis of essential hypertension and target-organ damage. 19 7 1982 1 10 1982 © 1983 The Biochemical Society and the Medical Research Society 1983 blood pressure hypertension ischaemic heart disease renin smoking Clinical Science (1983) 64,213-280 273 The epidemiology...
Clin Sci (Lond) (1982) 63 (s8): 403s–405s.
Published: 01 October 1982
...S. Freestone; L. E. Ramsay 1. Patients with mild hypertension who habitually smoked cigarettes and consumed caffeine were examined after abstaining from caffeine and cigarettes overnight. Their mean blood pressure (147/89 mmHg) was substantially lower than values recorded in the clinic (164/102...