... The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hes Hey Notch receptors pulmonary arteries signal transduction vascular smooth muscle cells...

.... Statistical significance was taken at P < 0.05. abdominal aortic aneurysm angiotensin II endoplasmic reticulum stress hypertension rupture signal transduction • No pharmacological treatment has been established that can inhibit or slow AAA development and rupture. We have shown...

... hyperplasia hypertension signal transduction Protein lysates were obtained by homogenizing SMCs with Triton-based lysis buffer (1% Triton X-100, 20 mM Tris/HCl, pH 7.4, 150 mM NaCl, 1 mM EDTA, 1 mM EGTA, 2.5 mM sodium pyrophosphate, 1 mM β-glycerol phosphate, 1 mM sodium orthovanadate, 1 μg/ml...

... and eventually the proteolysis rate balance. G-protein-coupled receptor (GPCR) kinin B 1 receptor muscle atrophy protein metabolism signal transduction ubiquitin–proteasome system • As the kinin B 1 receptor activates signalling pathways that are also known to be involved in skeletal...

... in macrophages [ 23 ]. In addition, the range in the molecular mass of Axl between 100 and 140 kDa might relate to post-translational modifications (glycosylation, phosphorylation and ubiquitination) and these will be discussed below. Figure 3 Axl receptor signal transduction Axl controls cell survival...

... andrew.redington@sickkids.ca ). 17 9 2010 17 11 2010 8 12 2010 8 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 β-catenin limb ischaemia myocardial infarction signal transduction remote ischaemic preconditioning The phenomenon of local IPC...

... hypothesize that FcγRs such as FcγRIIa could contribute to the pathogenesis of ALI/ARDS. acute lung injury FcγRIIa IgG receptor lung signal transduction ALI and the ARDS were first described in 1967 and represent a severe form of diffuse lung disease. Alternations of lung function...

... Society 2007 focal adhesion kinase (FAK) heart failure hypertrophy myocardial fibrosis signal transduction volume overload In conclusion, in the present study, we have investigated the expression, tyrosine phosphorylation and distribution of FAK in the volume-overloaded left ventricle from...

... Society 2005 angiogenesis inflammation signal transduction tumour vascular endothelial growth factor (VEGF) vascular permeability Angiogenesis and vasculogenesis are regulated predominantly by several different growth factors and their associated RTKs (receptor tyrosine kinases...

... to be identified. Correspondence: Dr Philip Newsholme (email philip.newsholme@ucd.ie ). 5 10 2004 10 11 2004 15 11 2004 15 11 2004 The Biochemical Society 2005 amino acids apoptosis diabetes gene expression metabolism mitochondria signal transduction It has...

... Nick Anim-Nyame (e-mail n.anim@ic.ac.uk ). 29 1 2003 19 6 2003 30 7 2003 30 7 2003 © 2004 The Biochemical Society 2004 blood flow conducted dilatation pre-eclampsia signal transduction Clinical Science (2004) 106, 19 25 (Printed in Great Britain) 19 Impaired...

... 2003 2003 angiopoietin-2 cell culture cyclical stretch gene expression signal transduction Tie receptor 421Clinical Science (2003) 104, 421 428 (Printed in Great Britain) Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein...

... factors. Recently, mutations in a G-protein (constitutively-activated Gs,) and in a seven-transmembrane-region receptor (constitutively Key words: cell proliferation, protein kinase, signal transduction. Abbreviations: E-Brd, &bromoadenosine 3',5'-cyclic monophosphate; CAMP, cyclic AMP; MAPK, mitogen...

... states that G-proteins undergo as they are activated and deactivated and has provided great insight into the kinetic models of G-protein-mediated signal transduction. 3. The regulation of adenylate cyclase has proven to be intriguing and complex. G sα activates all forms of mammalian adenylate cyclase...

...Samuel S. Lee; Jung-Min Pak; Shaun M. Medlicott; Arieh Bomzon 1. There is currently considerable interest in the role of locally produced vasodilators such as nitric oxide and adenosine in the pathogenesis of the peripheral vasodilatation of cirrhosis. However, the signal transduction pathways...