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Keywords: signal transduction
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Clin Sci (Lond) (2019) 133 (24): 2481–2498.
Published: 23 December 2019
... The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hes Hey Notch receptors pulmonary arteries signal transduction vascular smooth muscle cells...
Clin Sci (Lond) (2015) 128 (9): 559–565.
Published: 11 February 2015
.... Statistical significance was taken at P < 0.05. abdominal aortic aneurysm angiotensin II endoplasmic reticulum stress hypertension rupture signal transduction • No pharmacological treatment has been established that can inhibit or slow AAA development and rupture. We have shown...
Includes: Supplementary data
Clin Sci (Lond) (2012) 122 (8): 361–368.
Published: 14 December 2011
... in macrophages [ 23 ]. In addition, the range in the molecular mass of Axl between 100 and 140 kDa might relate to post-translational modifications (glycosylation, phosphorylation and ubiquitination) and these will be discussed below. Figure 3 Axl receptor signal transduction Axl controls cell survival...
Clin Sci (Lond) (2005) 109 (3): 227–241.
Published: 24 August 2005
... Society 2005 angiogenesis inflammation signal transduction tumour vascular endothelial growth factor (VEGF) vascular permeability Angiogenesis and vasculogenesis are regulated predominantly by several different growth factors and their associated RTKs (receptor tyrosine kinases...
Clin Sci (Lond) (2005) 108 (3): 185–194.
Published: 18 February 2005
... to be identified. Correspondence: Dr Philip Newsholme (email philip.newsholme@ucd.ie ). 5 10 2004 10 11 2004 15 11 2004 15 11 2004 The Biochemical Society 2005 amino acids apoptosis diabetes gene expression metabolism mitochondria signal transduction It has...
Clin Sci (Lond) (2003) 104 (4): 421–428.
Published: 20 March 2003
... 2003 2003 angiopoietin-2 cell culture cyclical stretch gene expression signal transduction Tie receptor 421Clinical Science (2003) 104, 421 428 (Printed in Great Britain) Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein...
Clin Sci (Lond) (1997) 92 (5): 445–451.
Published: 01 May 1997
... factors. Recently, mutations in a G-protein (constitutively-activated Gs,) and in a seven-transmembrane-region receptor (constitutively Key words: cell proliferation, protein kinase, signal transduction. Abbreviations: E-Brd, &bromoadenosine 3',5'-cyclic monophosphate; CAMP, cyclic AMP; MAPK, mitogen...
Clin Sci (Lond) (1996) 91 (5): 527–537.
Published: 01 November 1996
... states that G-proteins undergo as they are activated and deactivated and has provided great insight into the kinetic models of G-protein-mediated signal transduction. 3. The regulation of adenylate cyclase has proven to be intriguing and complex. G sα activates all forms of mammalian adenylate cyclase...
Clin Sci (Lond) (1995) 89 (3): 227–232.
Published: 01 September 1995
...Samuel S. Lee; Jung-Min Pak; Shaun M. Medlicott; Arieh Bomzon 1. There is currently considerable interest in the role of locally produced vasodilators such as nitric oxide and adenosine in the pathogenesis of the peripheral vasodilatation of cirrhosis. However, the signal transduction pathways...