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Keywords: shiga toxin
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Articles
Clin Sci (Lond) (2021) 135 (3): 575–588.
Published: 10 February 2021
... by Shiga toxin (Stx), is characterized by hemolytic anemia, thrombocytopenia and renal failure. The inflammatory response mediated by polymorphonuclear neutrophils (PMNs) and monocytes is essential to HUS onset. Still, the role of anti-inflammatory cytokines is less clear. The deficiency of IL-10, an anti...
Articles
Clin Sci (Lond) (2015) 129 (3): 235–244.
Published: 08 May 2015
... gastrointestinal infections that are Shiga toxin (Stx) producing. Monocytes contribute to HUS evolution by producing cytokines that sensitize endothelial cells to Stx action and migration to the injured kidney. As CC chemokine receptors (CCRs) are involved in monocyte recruitment to injured tissue, we analysed...