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Keywords: sex differences
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Clin Sci (Lond) (2018) 132 (17): 1953–1962.
Published: 14 September 2018
... sex differences Pregnant ewes were administered two intramuscular doses of 0.17 mg/kg BM acetate or saline (Control), 24 h apart at the 80th and 81st days of gestation. Offspring were delivered full term, farm-raised, and transferred to the Wake Forest School of Medicine Animal Facility...
Clin Sci (Lond) (2017) 131 (23): 2795–2805.
Published: 28 November 2017
...@monash.edu ) 12 07 2017 09 10 2017 03 11 2017 03 11 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 hypertension pregnancy relaxin sex differences Hypertension is the leading risk factor for cardiovascular...
Clin Sci (Lond) (2017) 131 (7): 533–552.
Published: 17 March 2017
...), sex hormones (oestrogen and androgen), epigenetic regulation and environmental factors all contribute to sex differences. Ischaemic sensitivity varies over the lifespan, with females having an “ischaemia resistant” phenotype that wanes after menopause, which has recently been modelled...
Clin Sci (Lond) (2016) 130 (10): 773–783.
Published: 01 April 2016
... despite the fact that both men and women develop hypertension. This is especially problematic since hypertension is well recognized as having distinct sex differences in the prevalence, absolute BP values and molecular mechanisms contributing to the pathophysiology of the disease. The purpose...
Clin Sci (Lond) (2016) 130 (10): 761–771.
Published: 01 April 2016
... hypertension sex differences Pregnancy is associated with significant cardiovascular and renal adaptations that facilitate the metabolic demands of the mother and the growing fetus. It has been demonstrated that normotensive pregnant women and gravid animal models are less sensitive to the pressor...
Clin Sci (Lond) (2016) 130 (8): 551–563.
Published: 08 March 2016
... © 2016 Authors; published by Portland Press Limited 2016 atherosclerosis heart failure heart rhythm sex differences women Despite the fact that cardiovascular disease is the leading cause of death for women, they have been significantly underrepresented in cardiovascular research...
Clin Sci (Lond) (2016) 130 (5): 337–348.
Published: 26 January 2016
... of chronic disease. Sex has an impact on the severity of cardiovascular risk in experimental models of developmental insult. Yet, few studies examine the influence of sex on blood pressure and cardiovascular health in low-birth weight men and women. Fewer still assess the impact of ageing on sex differences...
Clin Sci (Lond) (2016) 130 (5): 365–376.
Published: 26 January 2016
..., better cardiac function and less heart failure development. cardiac function fibrosis myocardial infarction oestrogen receptor β sex differences • The lower incidence of ischaemic cardiomyopathy in pre-menopausal women compared with age-matched men raises the crucial question about...
Includes: Supplementary data
Clin Sci (Lond) (1985) 69 (5): 587–593.
Published: 01 November 1985
...N. Orzes; S. Bellentani; R. Aldini; P. Simoni; I. Ferretti; G. C. Lunazzi; G. L. Sottocasa; C. Tiribelli 1. Sex difference in the hepatic uptake of sulphobromophthalein (BSP) was investigated in male and female rats in three different experimental models. 2. In the intact animal the BSP plasma...
Clin Sci (Lond) (1983) 64 (1): 85–90.
Published: 01 January 1983
...Maurizio Muraca; Jan De Groote; Johan Fevery 1. Hepatic bilirubin UDP-glucuronosyltransferase activity was higher in female than in male rats; gonadectomy decreased enzyme activity in females and increased it in males. This sex difference in bilirubin conjugation was further used to evaluate...