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Keywords: salt-sensitive hypertension
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Clin Sci (Lond) (2021) 135 (2): 259–274.
Published: 22 January 2021
... therapeutics salt-sensitive hypertension Hypertension is the leading risk factor for death and disability worldwide [ 1 ]. End-organ damage caused by hypertension can be effectively prevented by blocking the renin–angiotensin system (RAS), even when circulating RAS activity is low [ 2–4...
Includes: Supplementary data
Clin Sci (Lond) (2019) 133 (24): 2449–2461.
Published: 18 December 2019
... in salt-sensitive hypertension. However, mechanisms pertaining to the impact of K ir 4.1/K ir 5.1-mediated K + transport on the renin–angiotensin–aldosterone system (RAAS) remain unclear. Herein, we utilized a knockout of Kcnj16 in the Dahl salt-sensitive rat (SS Kcnj16-/- ) to investigate...
Includes: Supplementary data
Clin Sci (Lond) (1982) 63 (s8): 129s–132s.
Published: 01 October 1982
... as dual-mechanism diuretic agents with K + sparing properties and thus act as a novel class of antihypertensive drugs. © 1982 The Biochemical Society and the Medical Research Society 1982 aldosterone hydrochlorothiazide potassium riboflavin analogues salt-sensitive hypertension sodium balance...