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Keywords: renal secretion
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Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (14): 1631–1647.
Published: 30 June 2017
..., OCT3, OAT2, and OAT3. Cellular efflux is mediated by MATE1 and MATE-2K [ 76 ]. This rather complex transport and the involvement of many different transporters explain the variable effects of drugs on serum creatinine concentration. Renal secretion is most effectively inhibited by cimetidine, a drug...