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Keywords: renal function
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Articles
Clin Sci (Lond) (2018) 132 (18): 2071–2085.
Published: 22 September 2018
... of renal function including reductions in both glomerular filtration rate (GFR) and tubular handling of water and solutes. Although obstruction can be released by surgical operation, the child will suffer from diuresis for sometime. It has been reported that erythropoietin (EPO) could prevent the down...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2012) 122 (9): 429–437.
Published: 16 January 2012
..., endocrine and renal actions in experimental HF likely to be protective and compensatory in this setting. These results suggest that AM5 may have potential as a therapeutic agent in human HF. adenomedullin 5 haemodynamics heart failure hormone renal function Figure 3 Plasma cAMP, ANP...
Articles
Clin Sci (Lond) (2012) 122 (3): 105–111.
Published: 27 September 2011
...±0.24 μmol/l; P <0.001). SDMA levels were significantly correlated with markers of renal function. Kaplan–Meier survival analysis demonstrated that cumulative survival decreased significantly with ascending tertiles of SDMA ( P <0.001). Our study provides the first data indicating that SDMA...
Articles
Clin Sci (Lond) (2010) 119 (9): 373–387.
Published: 23 July 2010
... the linearity of the signal. Equal loading was confirmed by Coomassie Blue staining. developmental programming lifespan maternal diet renal function senescence stress response Aging is a biological process that is accompanied by a progressive decline in physiological functions, leading...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2010) 119 (8): 323–333.
Published: 06 July 2010
... model, and confirmed that short-term treatment was able to delay the progression of kidney cysts and protect renal function, which may relate to down-regulating the abnormally activated β-catenin signalling pathway and its anti-inflammatory and anti-fibrosis effects. Long-term administration...
Articles
Clin Sci (Lond) (2009) 116 (3): 257–263.
Published: 08 January 2009
... predictive of plasma copeptin. The present study suggests that gender and renal function specific partition values should be used to interpret copeptin values in future studies of this biomarker in HF or ischaemic heart disease. The sandwich immunoluminometric assay which was used to determine copeptin...
Articles
Clin Sci (Lond) (2008) 114 (10): 635–642.
Published: 14 April 2008
... in haemodynamics, hormonal profile and renal function than achieved by captopril alone. These results indicate that dual treatment with these two agents is beneficial. Correspondence: Dr Miriam T. Rademaker (email miriam.rademaker@chmeds.ac.nz ). 15 10 2007 26 11 2007 5 12 2007 5 12...
Articles
Clin Sci (Lond) (2007) 113 (7): 297–311.
Published: 03 September 2007
..., gastrointestinal responses, reproductive processes, renal effects etc. This review highlights recent insights into the role of each prostanoid in regulating various aspects of renal function, including haemodynamics, renin secretion, growth responses, tubular transport processes and cell fate. A thorough review...
Articles
Clin Sci (Lond) (2004) 106 (1): 27–34.
Published: 01 January 2004
...Pietro PANTALEO; Fabio MARRA; Francesco VIZZUTTI; Saura SPADONI; Giovanni CIABATTONI; Claudio GALLI; Giorgio LA VILLA; Paolo GENTILINI; Giacomo LAFFI Advanced cirrhosis is associated with reduced platelet function and altered renal function and sodium handling. Arachidonic acid (AA) metabolites...
Articles
Clin Sci (Lond) (2000) 98 (4): 439–444.
Published: 17 March 2000
... this was not a normal population, but one with a wide range of renal function, GFR/vECF showed a strong inverse association with age, whereas for GFR/BSA the association was weak. In conclusion, these data provide further evidence that vECF is more valid physiologically for indexing GFR than is BSA, especially...
Articles
Clin Sci (Lond) (1999) 97 (6): 681–687.
Published: 15 November 1999
... hypertension hypertension genetics hypertension pathogenesis insulin resistance lithium clearance renal function reninangiotensin system 681Clinical Science (1999) 97, 681 687 (Printed in Great Britain) Renal effects of hyperinsulinaemia in subjects with two hypertensive parents Ulrik B. ANDERSEN...
Articles
Clin Sci (Lond) (1998) 95 (1): 73–81.
Published: 01 July 1998
... interleukin-2 lithium clearance prostaglandins renal function sodium clearance 73Clinical Science (1998) 95, 73 81 (Printed in Great Britain) Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2 Poul F. GEERTSEN*, Hans VON DER MAASE...
Articles
Clin Sci (Lond) (1997) 92 (6): 579–585.
Published: 01 June 1997
... role in acute renal failure. In the present study we therefore investigated renal function and the renal ET system in rats on day 4 after bile-duct ligation (BDL) or sham-operation (SO), without ( n = 7 in each group) and with treatment with bosentan, a combined ET A /ET B receptor blocker, ( n = 5...
Articles
Clin Sci (Lond) (1994) 87 (4): 427–434.
Published: 01 October 1994
..., phosphoramidon. renal function. Abbreviations Cl,, clearance d [ Clinulin; ECE, endothelin-converting enzyme; ET-I, endothelin-I; FR fractional reabsorption of sodium; GFR, glomerular filtration rate; IPRK. isolated perfured rat kidney; MAP. mean systemic arterial blood pressure; RC, renal conductance; RCM...
Articles
Clin Sci (Lond) (1994) 87 (3): 329–335.
Published: 01 September 1994
... in cirrhosis, and reduced systemic vascular resistance has been suggested as a trigger to renal sodium retention in this disease. We investigated the effect of aprotinin, a protease inhibitor which binds to plasma kallikrein, on systemic haemodynamics and renal function in patients with hepatic cirrhosis...
Articles
Clin Sci (Lond) (1994) 86 (5): 599–610.
Published: 01 May 1994
... to renal function in an ovine model of progressive hyperdynamic sepsis. 2. Nine chronically instrumented unanaesthetized sheep were given a continuous intravenous infusion of Escherichia coli endotoxin (20 ng min −1 kg −1 ) for 3 days. 3. Within the first 12 h of infusion, endotoxin induced a major...
Articles
Clin Sci (Lond) (1993) 85 (5): 643–649.
Published: 01 November 1993
... positive end-expiratory pressure when the extracellular volume is not expanded. 5 4 1993 15 7 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 airway pressure atrial natriuretic peptide mechanical ventilation renal function renin-angiotensin system...
Articles
Clin Sci (Lond) (1993) 85 (2): 123–127.
Published: 01 August 1993
...C. F. Chen 1. Chronic hypoxic rats are always polycythaemic. It is possible that an increase in packed cell volume may enhance erythrocyte trapping with a consequent increase in renal damage after renal ischaemia. These experiments were designed to assess renal functional changes after renal...
Articles
Clin Sci (Lond) (1993) 85 (1): 19–26.
Published: 01 July 1993
... in clearing angiotensin II from the circulation. 8 3 1993 15 3 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 aldosterone angiotensin II atrial natriuretic peptide neutral endopeptidase renal function renin sodium balance Clinical Science (1993) 85...
Articles
Clin Sci (Lond) (1993) 84 (5): 531–535.
Published: 01 May 1993
... heart failure. 1 12 1992 27 1 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 cardiac hypertrophy cardiac output laser-Doppler flowmetry renal function thermodilution Clinical Science (1993) 84, 531-535 (Printed in Great Britain) Haemodynamic...
Articles
Clin Sci (Lond) (1993) 84 (2): 237–242.
Published: 01 February 1993
...Niels Vidiendal Olsen; Michael Hecht Olsen; Niels Fogh-Andersen; Bo Feldt-Rasmussen; Annelise Kamper; Inger Plum; Svend Strandgaard; Paul Peter Leyssac 1. The effect of a single dose of lithium on renal function before and during intravenous infusion of dopamine (3 μg min −1 kg −1...
Articles
Clin Sci (Lond) (1992) 83 (6): 711–715.
Published: 01 December 1992
...F. Zaladek Gil; V. L. Costa Silva; M. F. Cavanal; G. Malnic 1. The influence of thyroparathyroidectomy on renal function and specifically on acid excretion was studied in rats with or without oral supplementation of calcium. 2. Thyroparathyroidectomy caused a significant decrease in glomerular...
Articles
Clin Sci (Lond) (1992) 82 (5): 551–557.
Published: 01 May 1992
... significantly in the hypertensive group (0.22 ± 0.01 versus 0.26 ± 0.02, P < 0.05). A similar sustained antidiuresis was also observed after tryptophan administration in both groups. In addition, the above-described renal functional changes were not accompanied by any significant changes in systemic blood...
Articles
Clin Sci (Lond) (1992) 82 (2): 185–190.
Published: 01 February 1992
... by prolonged washout. 13 8 1991 9 9 1991 © 1992 The Biochemical Society and the Medical Research Society 1992 hypertension isolated rat kidney Milan hypertensive strain rats ouabain renal function Clinical Science ( 1992) 82, 185- I90 (Printed in Great Britain) Differences...
Articles
Clin Sci (Lond) (1991) 81 (s25): 465–470.
Published: 01 October 1991
...F. Zaladek Gil; V. L. Costa Silva; M. F. Cavanal 1. The influence of thyroparathyroidectomy and/or acidosis on renal function and specifically on acid excretion was studied in rats treated with a cumulative dose of 2 mg of aluminium. 2. Aluminium-treated and non-treated thyroparathyroidectomized...
Articles
Clin Sci (Lond) (1991) 80 (5): 427–433.
Published: 01 May 1991
...Allan D. Cumming; Adam Linton 1. The effect of the plasma protein concentration on renal function remains controversial. Most, but not all, experimental studies suggest that a reduced plasma protein concentration perfusing the kidney may reduce tubular sodium reabsorption. Hypoproteinaemic disease...
Articles
Clin Sci (Lond) (1991) 80 (2): 143–147.
Published: 01 February 1991
... Society and the Medical Research Society 1991 angiotensin II cirrhosis glomerular contraction glomeruli receptors renal function Clinical Science (1991) 80,143-147 ',143 Glomerular binding and contractile response to angiotensin I1 in rats with chronic experimental cirrhosis of the liver...
Articles
Clin Sci (Lond) (1990) 78 (6): 565–572.
Published: 01 June 1990
... intake dietary sodium intake renal function Clinical Science (1990) 78,565-572 565 Atrial natriuretic peptide and chronic renal effects of changes in dietary protein and sodium intake in man C . J. DOORENBOS, J. A. IESTRA, S . E. PAPAPOULOS", J. ODINKt AND P. VAN BRUMMELEN Department of Nephrology...
Articles
Clin Sci (Lond) (1990) 78 (2): 165–168.
Published: 01 February 1990
...Paolo Madeddu; Nicola Glorioso; Aldo Soro; Paolo Manunta; Chiara Troffa; Giancarlo Tonolo; Maria Grazia Melis; Antonio Pazzola 1. To evaluate whether sodium intake can modulate the action of endogenous kinins on renal function and haemodynamics, a receptor antagonist of bradykinin was infused...
Articles
Clin Sci (Lond) (1989) 77 (6): 643–650.
Published: 01 December 1989
... disease proteinuria renal function vascular permeability Clinical Science ( 1 989) 77,643-650 643 Effect of a-human atrial natriuretic peptide on proteinuria in patients with primary glomerular diseases MASAO ISHII, YASUNOBU HIRATA, TOKUICHIRO SUGIMOTO, HIROAKI MATSUOKA, KENJIRO KIMURA, TOSHIHIKO...
Articles
Clin Sci (Lond) (1989) 77 (1): 55–60.
Published: 01 July 1989
... for ANP-induced (intra)renal haemodynamic changes in ANP-induced natriuresis, possibly through an increase in the filtered load of sodium into a washed-out medullary interstitium. atrial natriuretic peptide hippuran extraction renal blood flow renal function renal sodium handling © 1989...
Articles
Clin Sci (Lond) (1989) 76 (3): 289–296.
Published: 01 March 1989
... clearance was unchanged. This observation may explain the failure of some previous studies to relate hypertension to impairment of renal function. 4. Plasma renin activity, plasma aldosterone and whole-body exchangeable sodium did not differ between normotensive and hypertensive patients with primary...
Articles
Clin Sci (Lond) (1989) 76 (1): 31–37.
Published: 01 January 1989
... positive airway pressure (CPAP) treatment. 2. To investigate the mechanisms of these changes in renal function, nocturnal urinary excretion of catecholamines and guanosine 3′:5′-cyclic monophosphate (cyclic GMP), which reflects atrial natriuretic factor (ANF) release, and next-morning plasma active renin...
Articles
Clin Sci (Lond) (1988) 74 (2): 137–143.
Published: 01 February 1988
... enhance renal sodium retention. 13 5 1987 30 7 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 aldosterone cirrhosis dopamine metoclopramide prolactin renal function renin Clinical Science ( 1988) 74. 137- 143 137 Unaltered dopaminergic modulation...
Articles
Clin Sci (Lond) (1987) 73 (6): 593–599.
Published: 01 December 1987
... pressure cardiac function chronic bile duct ligation eicosanoids mitochondrial function Na + K + -adenosine triphosphatase renal function ...
Articles
Clin Sci (Lond) (1987) 73 (2): 171–176.
Published: 01 August 1987
... endoperoxides into formation of vasodilator/natriuretic prostaglandins. These effects might be exaggerated and/or modified in conditions where arachidonic acid metabolism is stimulated. 9 10 1986 16 2 1986 © 1970 The Biochemical Society and the Medical Research Society 1970 renal function...
Articles
Clin Sci (Lond) (1987) 73 (2): 135–141.
Published: 01 August 1987
... I showed a greater increase in plasma noradrenaline and adrenaline ( P < 0.05). On multivariate analysis, those with lower systolic blood pressure, better renal function and more reactive sympathetic nervous system were discriminated as group I. 5. These data suggest that group I patients have...
Articles
Clin Sci (Lond) (1987) 73 (1): 87–92.
Published: 01 July 1987
... a physiological role in increasing sodium excretion to maintain osmolality after dehydration. 22 12 1986 2 2 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 antidiuretic hormone dehydration osmolality osmolarity renal function sodium sodium potassium...
Articles
Clin Sci (Lond) (1986) 71 (5): 533–538.
Published: 01 November 1986
... excretion. 13 6 1986 16 6 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 blood captopril pressure prostaglandin I 2 renal function renin ClinicalScience(1986) 71, 533-538 533 The contribution of PGI, to the effects of captopril in conscious dogs...
Articles
Clin Sci (Lond) (1986) 71 (5): 527–532.
Published: 01 November 1986
... in conscious dogs is 4 ng min −1 kg −1 body weight, which is substantially higher than that previously reported in man. 29 4 1986 29 4 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 blood pressure 6-keto-prostaglandin F 1α prostaglandin I 2 renal function...
Articles
Clin Sci (Lond) (1985) 69 (3): 293–298.
Published: 01 September 1985
... nephron water permeability. 11 2 1985 3 4 1985 © 1985 The Biochemical Society and the Medical Research Society 1985 counter-current mechanism indomethacin potassium prostaglandins renal function sodium urine concentration urine dilution vasopressin Clinical Science (1985...
Articles
Clin Sci (Lond) (1985) 68 (4): 387–393.
Published: 01 April 1985
...Herbert J. Kramer; Bruno Stinnesbeck; Georg Klautke; Jochen Kipnowski; Dietrich Klingmueller; Kilian Glaenzer; Rainer Duesing 1. In six healthy subjects the role of renal prostaglandins (PG) in modulating the actions of the renin-angiotensin and renal adrenergic nervous systems on renal function...
Articles
Clin Sci (Lond) (1982) 63 (6): 539–548.
Published: 01 December 1982
...Denise Laouari; Claire Kleinknecht; Giulia Cournot-Witmer; Renée Habib; Françoise Mounier; Michel Broyer 1. Diets deficient in phosphorus have been shown to preserve the renal function of uraemic rats, but the role of concomitant alterations in the intake of other nutrients caused by such diets...
Articles
Clin Sci (Lond) (1982) 63 (4): 387–392.
Published: 01 October 1982
... 1982 12 1 1982 19 5 1982 cirrhosis liver proteinuria renal function Clinical Science (1982) 63, 387-392 387 Proteinuria in patients with cirrhosis: relationship between renal and hepatic fbnction L. M I L A N I , A . G A T T A , C . M E R K E L A N D A. R U O L Universitci...
Articles
Clin Sci (Lond) (1981) 61 (1): 61–67.
Published: 01 July 1981
... 1981 The Biochemical Society and the Medical Research Society 1981 arginine vasopressin desaminoarginine vasopressin diabetes insipidus kallikrein plasma renin activity prostaglandins renal function CIinicalScience (1981) 61,61-67 61 Renal prostaglandins and water balance: studies...
Articles
Clin Sci (Lond) (1979) 57 (4): 359–365.
Published: 01 October 1979
... cause blood pressure to rise. 20 9 1978 2 5 1979 © 1979 The Biochemical Society and the Medical Research Society 1979 blood pressure hypertension indomethacin renal function prostaglandins prostaglandin synthesis inhibition Clinical Science (1979) 51,359-365 Effect...
Articles
Clin Sci (Lond) (1979) 56 (6): 547–553.
Published: 01 June 1979
... and in volume-expanded rats during the expansion phase, but not during stable expansion. 6. The results suggest that the kallikrein-kinin system may contribute to changes in renal function during extracellular volume expansion. This action may not necessarily be associated with changes in renal prostaglandin E...
Articles
Clin Sci Mol Med (1978) 55 (s4): 367s–371s.
Published: 01 December 1978
... plasma renin activity plasma and urinary electrolytes plasma volume renal function urinary aldosterone Clinical ScienceandMolecular Medicine (1918) 55,367s-311s Familial hypertension and hormonal profile, renal haemodynamics and body fluids of young normotensive subjects G . B I A N C H I , G. B...
Articles
Clin Sci Mol Med (1977) 52 (2): 205–213.
Published: 01 February 1977
... dipeptide hydrolysis dipeptide transport renal function Clinical Science and Molecular Medicine (1977) 52,205-213. Effect of nephrectomy and enterectomy on plasma clearance of intravenously administered dipeptides in rats S. A. ADIBI AND B. A. KRZYSIK Gastrointestinal and Nutrition Unit, Montefiore...
Articles
Clin Sci Mol Med (1976) 51 (s3): 249s–251s.
Published: 01 December 1976
... activity and plasma prostaglandin E 2 , but caused increased mean blood pressure (102 to 121 mmHg, sem 4 and 6 respectively; P < 0·01) and decreased renal function (plasma creatinine 0·9 ± 0·04 to 3·5 ± 1 mg/100 ml, sem 0·04 and 1 respectively; P < 0·01). 6. Aggravation of hypertension...