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Keywords: renal blood flow
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Clin Sci (Lond) (2018) 132 (13): 1453–1470.
Published: 18 July 2018
... on behalf of the Biochemical Society 2018 glomerular filtration rate hyperfiltration renal blood flow UCHL1 UCH-L1 Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme that salvages ubiquitin from substrates and preserves intracellular ubiquitin pools. UCHL1 is largely...
Includes: Supplementary data
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Clin Sci (Lond) (2005) 109 (3): 311–317.
Published: 24 August 2005
... pretreatment with 150 mg of irbesartan once a day for 5 consecutive days. RPF (renal plasma flow) and GFR (glomerular filtration rate) were also measured. Before Ang II infusion, the PFH and NFH groups did not differ with respect to BP (blood pressure), body mass index, PRA, RBF (renal blood flow) or urinary...
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Clin Sci (Lond) (1998) 95 (6): 693–699.
Published: 01 December 1998
...Nadine MAYBAUM; Elena GORODETSKY; Marta WEINSTOCK 1. We have previously shown that normotensive rabbits with a genetic impairment in arterial baroreflex sensitivity showed a delayed sodium excretion and failed to increase their renal blood flow in response to a saline infusion that did not alter...
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Clin Sci (Lond) (1997) 92 (5): 433–443.
Published: 01 May 1997
...Kevin Moore 1. The hepatorenal syndrome is the development of renal failure in patients with severe liver disease in the absence of any identifiable renal pathology. 2. Decreased glomerular filtration is caused by a reduction in both renal blood flow and the renal filtration fraction. These changes...
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Clin Sci (Lond) (1994) 87 (2): 143–149.
Published: 01 August 1994
...Anders Edlund; Hans Ohlsén; Alf Sollevi 1. The effects of local intra-arterial infusion of adenosine on renal blood flow, glomerular filtration and renin release in eight healthy awake subjects have been examined. 2. Renal blood flow and glomerular filtration rate were measured as the clearances...
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Clin Sci (Lond) (1991) 81 (6): 727–732.
Published: 01 December 1991
.... 2. Mean arterial blood pressure, heart rate and cardiac output were not changed significantly by l -arginine infusion. However, l -arginine infusion induced a significant elevation of renal blood flow from 50 ± 3 to 94 ± 12 ml/min (means ± sem , P < 0.01). 3. Simultaneous infusion of N G...
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Clin Sci (Lond) (1990) 79 (6): 551–558.
Published: 01 December 1990
... antagonists BN-52021 (1 mg/kg, intraperitoneally) and alprazolam (1 and 5 mg/kg, intraperitoneally) on the evolution of glomerular filtration and renal blood flow, in the experimental model of acute renal failure induced by the intramuscular injection of glycerol in rats. 2. We have also measured...
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Clin Sci (Lond) (1989) 77 (5): 567–572.
Published: 01 November 1989
.... In contrast with the various changes in systemic haemodynamics, renal blood flow transiently increased immediately after bolus injection in a dose-dependent manner (28%, P < 0.05, 50%, P < 0.01 and 110%, P < 0.01 with 4, 40 and 200 pmol of endothelin/kg, respectively). This transient elevation...
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Clin Sci (Lond) (1988) 74 (1): 63–69.
Published: 01 January 1988
...S. B. Harrap; A. E. Doyle 1. To determine the relevance of renal circulatory abnormalities found in the immature spontaneously hypertensive rat (SHR) to the genetic hypertensive process, glomerular filtration rate and renal blood flow were measured in conscious F 2 rats, derived from crossbreeding...
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Clin Sci (Lond) (1987) 72 (6): 657–667.
Published: 01 June 1987
... a control period, during CEI (teprotide, 3 mg h −1 kg −1 ) infusion and during a third period of verapamil (600 μg h −1 kg −1 ) infusion superimposed on CEI infusion. 2. Although systemic blood pressure (BP) decreased from 175 ± 4 to 149 ± 5 mmHg (mean ± SEM) in response to verapamil alone, renal blood flow...
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Clin Sci (Lond) (1987) 72 (4): 429–436.
Published: 01 April 1987
...Margrethe E. Olsen; John E. Hall; Jean-Pierre Montani; John E. Cornell 9 7 1986 24 10 1986 © 1970 The Biochemical Society and the Medical Research Society 1970 angiotensin II autoregulation glomerular filtration rate prostaglandins renal blood flow tubuloglomerular...
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Clin Sci (Lond) (1986) 71 (3): 323–325.
Published: 01 September 1986
... in sodium excretion and a 310% increase in urine flow. Mean arterial pressure decreased by 21 mmHg and the peripheral resistances decreased by 26%, without significant changes in cardiac output. 3. Renal blood flow increased by 37.7% and small intestine and portal blood flow increased by 39% and by 28...
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Clin Sci (Lond) (1986) 70 (3): 243–247.
Published: 01 March 1986
... prostaglandin E 2 renal blood flow renin sulindac Clinical Science (1986) 70, 243-241 243 Chronic effects of oral sulindac on renal haemodynamics and hormones in subjects with chronic renal disease CHARLES P. SWAINSON, PETER GRIFFITHS A N D MICHAEL L. WATSON Department of Medicine, Christchurch Clinical...
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Clin Sci (Lond) (1983) 65 (5): 533–538.
Published: 01 November 1983
... neither renal blood flow nor glomerular filtration rate responses to decreasing renal perfusion pressure. 3. Hypercapnic acidosis ( P co 2 71 ±2 mmHg; pH 7.03 ± 0.01) significantly decreased both renal blood flow and glomerular filtration rate as renal perfusion pressure was lowered. This effect...
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Clin Sci (Lond) (1983) 65 (1): 47–55.
Published: 01 July 1983
...- and water-deprived rats. 3. Glomerular filtration rate and renal blood flow were not affected by atrial extract, indicating that the atrial natriuretic factor (ANF) directly inhibited sodium reabsorption at the tubular level. 4. Distal tubular blockade with a combination of frusemide and amiloride...
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Clin Sci (Lond) (1982) 62 (6): 573–579.
Published: 01 June 1982
... blood pressure from 164 ± 4 to 124 ± 4 mmHg. Despite the profound fall of arterial pressure, significant increases in renal blood flow from 5.82 ± 0.22 to 9.15 ± 0.76 ml/min and glomerular filtration rate from 1.46 ± 0.10 to 2.18 ± 0.14 ml/min were observed in the non-clipped kidneys. Renal vascular...
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Clin Sci (Lond) (1980) 59 (s6): 87s–90s.
Published: 01 December 1980
... blood pressure converting enzyme inhibition glomerular filtration rate renal blood flow sodium excretion Clinical Science (1980) 59,87~-90s 87s Long-term regulation of arterial pressure, glomerular filtration and renal sodium reabsorption by angiotensin I1 in dogs J . E. H A L L , A . C . G U Y T...
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Clin Sci (Lond) (1980) 59 (s6): 381s–384s.
Published: 01 December 1980
... blood pressure. 2. At their respective spontaneous blood pressures, renal vascular resistance was higher and glomerular filtration rate (GFR) and renal blood flow were not different in the contralateral kidneys of the hypertensive rats (170 ± 5 mmHg) compared with normal animals (129 ± 1 mmHg). Urine...
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Clin Sci (Lond) (1979) 57 (s5): 421s–423s.
Published: 01 December 1979
... and the Medical Research Society 1979 captopril essential hypertension renal blood flow renin CIinicalScience (1979) 51.421s-423~ Effect of captopril on renal vascular tone in patients with essential hypertension A. MIMRAN, H. R. B R U N N E R , G . A. T U R I N I , B. WAEBER AND D. BRUNNER Department...
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Clin Sci Mol Med (1978) 55 (4): 335–339.
Published: 01 October 1978
... an increase in GFR not dependent on an increase in whole-kidney plasma flow. 20 12 1977 8 5 1978 © 1978 The Biochemical Society and the Medical Research Society 1978 glomerular filtration rate prolactin renal blood flow Clinical Science and Molecular Medicine (1978) 55,335-339...
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Clin Sci Mol Med (1977) 52 (5): 545–548.
Published: 01 May 1977
... intrarenal effects which lead to salt and water retention. 19 1 1977 7 2 1977 © 1977 The Biochemical Society and the Medical Research Society 1977 angiotensin II antagonist electrolyte excretion glomerular filtration rate renal blood flow Clinical Science and Molecular Medicine...
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Clin Sci Mol Med (1976) 51 (6): 583–588.
Published: 01 December 1976
...W. R. Withey; B. J. Chapman; K. A. Munday 1. Renal function was measured in seven normo thermic (38°C) and seven hypothermic (27°C) dogs. 2. The glomerular filtration rate was 60% lower in the hypothermic animals, and the renal blood flow was 51% lower. The intrarenal distribution of blood flow...
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Clin Sci Mol Med (1976) 51 (s3): 641s–643s.
Published: 01 December 1976
...) were investigated in twelve patients with essential hypertension. 2. The anti-hypertensive action of both compounds was similar and was accompanied by a reduction in heart rate and in cardiac output, total peripheral resistance being unchanged. There was no alteration in renal blood flow and glomerular...
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Clin Sci Mol Med (1976) 51 (s3): 373s–375s.
Published: 01 December 1976
... only when the sino-aortic reflexes are intact. © 1976 The Biochemical Society and the Medical Research Society 1976 arterial pressure carotid sinus mesenteric blood flow muscle blood flow renal blood flow sympathetic nervous system Clinical Science and Molecular Medicine (1976) 51, 3739...
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Clin Sci Mol Med (1976) 51 (s3): 605s–607s.
Published: 01 December 1976
...A. Wester; G. A. Zaal; P. W. De Leeuw; W. H. Birkenhäger 1. In eighteen subjects with mild to moderate hypertension the effectiveness of the new vasodilator drug L6150 (Lepetit) was studied. Its mechanism of action was identified by systemic and renal blood flow measurements and by estimating...
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Clin Sci Mol Med (1976) 50 (3): 177–184.
Published: 01 March 1976
...J. Yudkin; R. D. Cohen; Barbara Slack 1. The effect of metabolic acidosis of 4–6 h duration on cardiac output, blood pressure, heart rate, and hepatic and renal blood flow has been studied in the rat. 2. In anaesthetized rats, blood pressure and heart rate fell linearly with blood pH in both sham...
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Clin Sci Mol Med (1975) 48 (6): 533–535.
Published: 01 June 1975
...D. J. Warren; J. G. G. Ledingham 1. The effect of propranolol on total and regional renal blood flow was measured in conscious rabbits after 6 days on normal or low sodium diets. 2. Propranolol inhibited the fall in total superficial cortical renal blood flow which occurred in response to the low...
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Clin Sci Mol Med (1975) 48 (1): 51–60.
Published: 01 January 1975
...D. J. Warren; J. G. G. Ledingham 1. Total renal blood flow and its distribution within the renal cortex of the conscious rabbit were studied with radioactive microspheres of 15 and 25 μm diameter. 2. The reliability of the microsphere technique was influenced by microsphere diameter and number...
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Clin Sci Mol Med (1975) 48 (s2): 299s–302s.
Published: 01 January 1975
... of the renin-angiotensin system. 3. Indomethacin induced a decrease in renal blood flow. 4. Angiotensin receptor blockade with Sar 1 -Ala 8 -angiotensin II blunted the blood pressure effect and prevented the renal haemodynamic changes induced by indomethacin. © 1975 The Biochemical Society and the Medical...
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Clin Sci Mol Med (1973) 45 (s1): 243s–246s.
Published: 01 August 1973
... in the contralateral denervated kidney. Renal blood flow markedly decreases in the innervated, and remains unchanged in the denervated, kidney during pontine stimulation. 2. Blockade of the vasomotor response to pontine stimulation in one kidney by close arterial infusion of phenoxybenzamine does not reduce the renin...
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Clin Sci (1972) 43 (3): 401–411.
Published: 01 September 1972
... by an indicator-dilution technique. 2. Increases in renal blood flow during graded intravenous iso-osmotic saline or hyperosmotic mannitol infusions and during renal arterial infusions of acetylcholine or prostaglandin E 1 were consistently associated with reduced E PAH . 3. The cortical fraction of renal blood...
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