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Keywords: proteomics
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Clin Sci (Lond) (2018) 132 (19): 2117–2120.
Published: 05 October 2018
... on behalf of the Biochemical Society 2018 epidermal growth factor receptor fibrosis paracrine signalling proteomics Hypertension is a well-known contributor to the development of cardiovascular diseases and serves as an early prognostic factor for ailments such as ischemic heart disease...
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Clin Sci (Lond) (2016) 130 (12): 1027–1038.
Published: 06 May 2016
... from four AAA patients and four controls were analysed by a label-free proteomic approach. Among identified proteins, paraoxonase-1 (PON1) was decreased in plasma of AAA patients compared with controls, which was further validated in a bigger cohort of samples by ELISA. The phenylesterase enzymatic...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 129 (1): 27–38.
Published: 01 April 2015
... mechanism and causal risk factors for plaque rupture remain unclear. To identify a potential molecule that can influence atherosclerotic plaque rupture, we investigated protein expression in serum from patients with acute myocardial infarction (AMI) and stable angina (SA), using proteomic analysis...
Includes: Supplementary data
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Clin Sci (Lond) (2009) 116 (9): 721–730.
Published: 02 April 2009
... and high mortality rate. Its pathophysiology and molecular mechanisms are complicated and remain poorly understood. In the present study, we performed a proteomics investigation to characterize early host responses to sepsis as determined by an altered plasma proteome in a porcine model of peritonitis...
Includes: Supplementary data
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Clin Sci (Lond) (2005) 109 (5): 421–430.
Published: 24 October 2005
...Bernardo C. Vidal, Jr; Joseph V. Bonventre; Stephen I-Hong Hsu Proteomics is widely envisioned as playing a significant role in the translation of genomics to clinically useful applications, especially in the areas of diagnostics and prognostics. In the diagnosis and treatment of kidney disease...
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Clin Sci (Lond) (2005) 108 (5): 369–383.
Published: 22 April 2005
...Walter KOLCH; Harald MISCHAK; Andrew R. PITT The enormous progress in proteomics, enabled by recent advances in MS (mass spectrometry), has brought protein analysis back into the limelight of cancer research, reviving old areas as well as opening new fields of study. In this review, we discuss...
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Clin Sci (Lond) (2004) 107 (5): 485–495.
Published: 26 October 2004
... indicative of ‘diabetic renal damage’. We also found this pattern in 35% of those patients who had low-grade albuminuria and in 4% of patients with normal albumin excretion. Moreover, we could identify several of the indicative polypeptides using MS/MS sequencing. We conclude that proteomic analysis with CE...
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