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Keywords: portal hypertension
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Clin Sci (Lond) (2022) 136 (6): 425–429.
Published: 25 March 2022
...Emilie K. Mitten; György Baffy In this commentary, we discuss new findings indicating that microbiota transplantation has favorable impact on portal hypertension (PH) in the experimental model of cirrhosis induced by bile duct ligation (BDL) (Huang et al.; Clin Sci (Lond) (2021) 135(24): 2709–2728...
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Clin Sci (Lond) (2018) 132 (12): 1341–1343.
Published: 28 June 2018
...Audrey Payancé; Pierre-Emmanuel Rautou Data on the consequences of cirrhosis regression on portal hypertension and on splanchnic and systemic hemodynamic are scarce. Previous studies have reported a decrease in hepatic venous pressure gradient following antiviral treatment in patients...
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Clin Sci (Lond) (2017) 131 (1): 69–86.
Published: 09 December 2016
... intrahepatic resistance, increased portal-systemic collaterals and abnormal intra- and extra-hepatic vascular responsiveness. These derangements aggravate portal hypertension-related complications such as gastro-oesophageal variceal bleeding. Homocysteine, a substance implicated in cardiovascular diseases, has...
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Clin Sci (Lond) (2015) 129 (10): 875–883.
Published: 01 September 2015
... Roberto Lambertucci; Anna Mae Diehl Schistosomiasis is a major cause of portal hypertension worldwide. It associates with portal fibrosis that develops during chronic infection. The mechanisms by which the pathogen evokes these host responses remain unclear. We evaluated the hypothesis that schistosome...
Includes: Supplementary data
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Clin Sci (Lond) (2013) 125 (2): 67–75.
Published: 26 March 2013
... 2013 6 2 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 calcium receptor experimental liver cirrhosis liver plasma flow portal hypertension • The death rate from portal hypertensive bleeding in cirrhotic patients is still high. The role of calcium...
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Clin Sci (Lond) (2012) 123 (4): 225–239.
Published: 24 April 2012
... to the pathophysiology of portal hypertension in cirrhosis. Although the intrahepatic circulation in cirrhosis is hypercontractile in response to AngII, resulting in increased hepatic resistance, the splanchnic vasculature is hyporesponsive, promoting the development of the hyperdynamic circulation that characterizes...
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Clin Sci (Lond) (2002) 103 (1): 43–51.
Published: 07 June 2002
... portal hypertension spectral analysis systemic haemodynamics transcranial Doppler. 43Clinical Science (2002) 103, 43 51 (Printed in Great Britain) Impaired sympathetic regulation of cerebral blood flow in patients with cirrhosis of the liver Alfonso LAGI*, Giacomo LAFFI , Simone CENCETTI*, Giuseppe...
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Clin Sci (Lond) (2000) 99 (5): 455–460.
Published: 27 October 2000
... channels. Correspondence : Dr Noemí M. Atucha (e-mail ntma@fcu.um.es ). 10 3 2000 27 6 2000 26 7 2000 The Biochemical Society and the Medical Research Society © 2000 2000 isolated and perfused mesentery liver cirrhosis methoxamine nitric oxide portal hypertension...
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Clin Sci (Lond) (1998) 96 (1): 41–47.
Published: 01 January 1999
...Claire CONNOLLY; Teresa CAWLEY; P. Aiden MCCORMICK; James R. DOCHERTY We have examined the effects of pre-hepatic portal hypertension on the responsiveness of aorta from Wistar and Sprague–Dawley rats. Rats were made portal hypertensive by creating a calibrated portal vein stenosis, or sham...
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Clin Sci (Lond) (1998) 94 (6): 645–650.
Published: 01 June 1998
...Han-Chieh Lin; Yi-Tsau Huang; Yuh-Ren Cheng; Ming-Chih Hou; Fa-Yauh Lee; Full-Young Chang; Yang-Te Tsai; Shou-Dong Lee 1. Both octreotide and isosorbide dinitrate have been shown to have portal hypotensive effects in animals with portal hypertension. Moreover, in both animals and humans with portal...
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Clin Sci (Lond) (1997) 93 (3): 219–225.
Published: 01 September 1997
...Chi-Jen Chu; Fa-Yauh Lee; Sun-Sang Wang; LU Rei-Hwa; Yang-Te Tsai; Han-Chieh Lin; Ming-Chih Hou; Che-Chang Chan; Shou-Dong Lee 1. Hyperdynamic circulation observed in portal hypertensive states is characterized by generalized vasodilatation, increased cardiac index and increased systemic...
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Clin Sci (Lond) (1997) 92 (5): 433–443.
Published: 01 May 1997
... cirrhosis hepatorenal syndrome portal hypertension renal blood flow Clinical Science (1997) 92,433-443 (Printed in Great Britain) 433 Editorial Review The hepatorenal syndrome Kevin MOORE Department of Medicine, Royal Free Hospital School of Medicine, London, U. K. 1. The hepatorenal syndrome...
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Clin Sci (Lond) (1993) 84 (2): 185–192.
Published: 01 February 1993
... cirrhosis isolated perfused rat liver portal hypertension portal pressure Clinical Science (1993) 84, 185492 (Printed in Great Britain) I85 Augmented portal flow in the isolated perfused cirrhotic rat liver: a haemodynamic and morphological study Jorge E. CARDOSO', Yvon CALMUS', Claire LEGENDRE2...
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Clin Sci (Lond) (1989) 77 (1): 7–9.
Published: 01 July 1989
..., the beneficial effect of somatostatin analogue for the treatment of gastrointestinal bleeding due to portal hypertension. They suggest that administration of this substance should be started as soon as possible after the beginning of haemorrhage and continued after the cessation of bleeding. 13 2 1989...
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Clin Sci (Lond) (1988) 74 (4): 433–436.
Published: 01 April 1988
... is also associated with age-related decreases in peripheral haemodynamics. Key words: forearm blood flow, portal hypertension, systemic circulation. INTRODUCTION Cirrhosis is associated with a hyperkinetic circulation manifested by increased cardiac output and decreased systemic vascular resistance...
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Clin Sci (Lond) (1986) 71 (6): 743–747.
Published: 01 December 1986
... of this study was to investigate clinical conditions in which increased Droduction of prostacyclin has been reported* 6-ox0- Key words: atheroma, portal hypertension, prosta- prostaglandin F,, (6-oxo-PGF1,) is the stable hydro- lysis product of PGI, and was measured in plasma cyclin, surgery. Abbreviations: GC...
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Clin Sci (Lond) (1985) 68 (1): 23–28.
Published: 01 January 1985
...D. Lebrec; L. Blanchet 1. Splanchnic organ blood flow and cardiac output were measured by the microsphere method in fasted rats with prehepatic portal hypertension due to portal vein stenosis, in rats with intrahepatic portal hypertension due to bile duct ligation, and in unoperated normal rats. 2...
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Clin Sci (Lond) (1982) 63 (1): 29–32.
Published: 01 July 1982
... in portal blood flow which is related, in part, to a reduction in cardiac output; (c) propranolol does not alter hepatic blood flow in normal rats or in rats with portal hypertension. 21 9 1981 26 1 1982 11 12 1981 © 1982 The Biochemical Society and the Medical Research Society 1982...