... and may result in disease. This literature review examines the current evidence for the role of oxidative stress in important ocular diseases with a view to identifying potential therapeutic targets for future study. The need is particularly pressing in developing treatments for conditions which remain...

... 14 3 2008 14 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 adenovirus gene therapy haem oxygenase ischaemia/reperfusion ocular disease retinal ganglion cell Retinal IR (ischaemia/reperfusion) injury, leading to RGC (retinal ganglion cell...

... for delivery of therapeutic genes to treat neurological and ocular diseases, since they efficiently transduce non-dividing cells and mediate sustained transgene expression. Furthermore, novel routes of vector delivery to the nervous system have recently been elucidated and these have increased further...