... restriction glucose transport insulin resistance intracellular cross-talk non-esterified fatty acids reninangiotensin system Correspondence: Dr Colin Perry (e-mail colin@fulcrum.u-net.com ). 12 11 2002 8 4 2003 29 4 2003 29 4 2003 © 2003 The Biochemical Society 2003...

... adhesion molecules atherosclerosis diet endothelial dysfunction fish oil non-esterified fatty acids Clinical Science (2003) 105, 13 20 (Printed in Great Britain) 13 Supplementation with fish oil affects the association between very long-chain n-3 polyunsaturated fatty acids in serum non-esterified...

... catheter technique. Haemodynamic state was assessed with the aid of Swan–Ganz catheters. High-dose GIK caused a shift towards carbohydrate utilization, with significant lactate uptake throughout the study period and significant uptake of glucose after 4 h. Arterial levels of non-esterified fatty acids...

...L. RANGANATH; F. NORRIS; L. MORGAN; J. WRIGHT; V. MARKS Two studies were performed to assess the entero-insular axis in simple obesity and the possible effect of variations in the level of circulating non-esterified fatty acids (NEFA) on one of the components of the entero-insular axis, glucagon...

...Keith N. Frayn; Christine M. Williams; Peter Arner coronary heart disease insulin resistance non-esterified fatty acids non-insulin-dependent diabetes obesity stress Clinical Science (1996) W, 243-253 (Printed in Great Britain) Editorial Review 243 Are increased plasma non-esterified...

... is independent of blood flow) was assessed: for triacylglycerol it was significantly greater in the fed state ( P < 0.01). The sum of the potential contributions of triacylglycerol, non-esterified fatty acids, glucose and ketone bodies to forearm O 2 consumption was significantly greater, both before...

... adipocytes. 2. Oral administration of GR79236 (0.1-10 mg/kg) to fed rats induced minimal changes in the plasma concentration of non-esterified fatty acids and in the blood concentrations of glucose and lactate. 3. Intravenous infusion of GR79236 to fasted pithed rats, or oral administration of GR79236...

... glycerol levels after meals but normal suppression of serum non-esterified fatty acid concentrations. The greatest differences in the profiles of serum lipids and lipid-related metabolites in cirrhotic patients and control subjects occurred at night. Whereas in control subjects, serum non-esterified fatty...

..., by increasing the rate of gluconeogenesis and therefore hepatic glucose output. Despite this relationship between lipid and carbohydrate metabolism, fasting glucose concentrations do not fall acutely in patients with non-insulin-dependent diabetes mellitus when plasma non-esterified fatty acid concentrations...

...Keith N. Frayn; Simon W. Coppack © 1992 The Biochemical Society and the Medical Research Society 1992 adipose tissue coronary heart disease insulin insulin resistance lipoproteins non-esterified fatty acids triacylglycerol Clinical Science (1992) 82, 1-8 (Printed in Great Britain...

...M. Walker; B. G. Cooper; C. Elliott; J. W. Reed; H. Orskov; K. G. M. M. Alberti 1. The importance of circulating non-esterified fatty acids as a substrate during and after low-grade exercise has been examined by using a nicotinic acid analogue to inhibit lipolysis. Seven healthy men received...

... immunodeficiency syndrome fasting glucose lipolysis non-esterified fatty acids triacylglycerols tumour necrosis factor 29 10 1990 21 11 1990 © 1991 The Biochemical Society and the Medical Research Society 1991 Clinical Science (1991) 80,359-365 359 Basal fuel homoeostasis...

...% above control level. 6. Plasma glucose and glycerol concentrations remained unchanged, and plasma non-esterified fatty acids, lactate and noradrenaline concentrations increased slightly but significantly. 7. Biopsies taken from the hot interscapular areas did not contain brown adipose tissue. 8...

... at intervals of 1 week by intravenous infusions of 3, 4 or 6 units of insulin/h, or by intravenous injection of 0.15 unit/kg body weight. 3. Plasma glucose reached nadir values of 2.08 ±0.10, 1.82 ± 0.21, 1.24 ±0.08 and 0.92 ± 0.06 mmol/l (means ± sem) in the four experiments. Non-esterified fatty acid levels...

...H. B. Stoner; K. N. Frayn; R. A. Little; C. J. Threlfall; D. W. Yates; R. N. Barton; D. F. Heath 1. Plasma concentrations of glucose, lactate, amino acids, non-esterified fatty acids, glycerol, ketone bodies, insulin and cortisol were measured in 43 elderly patients with hypothermia. In 15...

...H. B. Stoner; K. N. Frayn; R. N. Barton; C. J. Threlfall; R. A. Little 1. The plasma concentrations of glucose, lactate, amino acids, non-esterified fatty acids, glycerol, ketone bodies, ethanol, cortisol and insulin were measured in patients within a few hours of injury and before treatment...

... tension and heart rate, followed shortly thereafter by marked deterioration in mechanical performance to levels below those observed in the control state. These latter responses occurred simultaneously with stimulation of endogenous myocardial lipolysis. The rate of release of non-esterified fatty acids...

...V. Gentil; M. H. Lader; B. D. Kantamaneni; G. Curzon 1. Subcutaneous injection of adrenaline into normal male volunteer subjects caused large increases of plasma non-esterified fatty acids and free tryptophan, but plasma total tryptophan fell considerably. Therefore increases of the percentage...

...R. E. Cowan; R. P. H. Thompson; J. P. Kaye; Gillian M. Clark 1. The concentrations of plasma total and unconjugated bilirubin and of serum non-esterified fatty acids (NEFA) have been measured in two healthy subjects during fasts of up to 21 h. 2. Fasting was either continuous or interrupted...

... in both groups. 3. High fasting concentrations of non-esterified fatty acid (NEFA) were recorded in the choreic patients when compared with control subjects. This difference was maintained under hypoglycaemic conditions. However, during hyperglycaemia the differences in NEFA concentrations between...

...N. E. Miller; O. D. Mjøs; M. F. Oliver 1. The mechanism whereby p -chlorophenoxyisobutyrate (CPIB) lowers plasma non-esterified fatty acid concentrations has been studied in dogs by measuring the associated changes in adipose tissue metabolism. 2. CPIB lowered arterial concentrations of non...

...S. Landin; L. Hagenfeldt; B. Saltin; J. Wahren 1. Arterial concentrations and leg exchange of carbohydrate substrates and non-esterified fatty acids (NEFA) were examined together with concentrations of intramuscular metabolites at rest and during exercise in six patients with Parkinson's disease...