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Keywords: natriuresis
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Articles
Clin Sci (Lond) (2020) 134 (7): 871–884.
Published: 14 April 2020
... of β-Pro 7 -Ang III elicited renal vasodilatation and natriuresis. Notably, greater renal vasodilatory effects were observed in female versus male rats at the highest dose of β-Pro 7 -Ang III administered. Moreover, intra-renal administration of β-Pro 7 -Ang III produced significant natriuretic effects...
Articles
Clin Sci (Lond) (2019) 133 (9): 1097–1113.
Published: 09 May 2019
...) . Cold exposure central AT1 receptor hypertension natriuresis prenatal programing sympathetic nervous system Hypertension is the leading cause of death and other cardiovascular diseases globally [ 1 , 2 ]. Several pieces of evidence have shown the association between the environment...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2012) 123 (12): 659–668.
Published: 10 August 2012
... there may be other sites of synthesis, including the kidney tubules. Products from pro-uroguanylin may mediate natriuresis following oral consumption of a salt load through both GC-C (guanylate cyclase C)-dependent and -independent mechanisms, and recent evidence suggests a role in appetite regulation...
Articles
Clin Sci (Lond) (2012) 122 (2): 63–73.
Published: 20 September 2011
...Jane A. Simonsen; Mona S. Rasmussen; Werner Vach; Poul F. Høilund-Carlsen; Peter Bie NO (nitric oxide) may be involved in fluid homoeostasis. We hypothesized that increases in NO synthesis contribute to acute, saline-induced natriuresis, which, therefore, should be blunted when NO availability...
Articles
Clin Sci (Lond) (2007) 112 (9): 485–491.
Published: 02 April 2007
... of Ucn1 on natriuretic peptides, ET-1 and other neurohumoral indices should also be studied under other experimental paradigms. Ucn1 exhibits significant renal effects in sheep with pacing-induced heart failure, including diuresis and natriuresis [ 3 , 4 ]; however, such effects are not apparent...
Articles
Clin Sci (Lond) (2002) 103 (5): 461–466.
Published: 03 October 2002
.... Correspondence : Dr D.G. Shirley (e-mail david.shirley@ucl.ac.uk ). 25 2 2002 10 7 2002 24 7 2002 The Biochemical Society and the Medical Research Society ©2002 2002 caffeine lithium clearance natriuresis proximal tubule 461Clinical Science (2002) 103, 461 466 (Printed...
Articles
Clin Sci (Lond) (1998) 95 (2): 195–202.
Published: 01 August 1998
... or CNP. At peak AVO, urinary CNP excretion was increased compared with baseline (7.0±4.2 versus 62±8.0 ;pg/min, P < 0.05). 3. In the HS-142-1-treated group, plasma cGMP was decreased compared with the control group (9.6±1.1 to 5.0±1.2 ;pmol/ml, P < 0.05). A significant attenuation of natriuresis...
Articles
Clin Sci (Lond) (1997) 92 (4): 409–414.
Published: 01 April 1997
...G. S. Stokes; J. C. Monaghan; D. N. Pillai 1. Dopamine and prostaglandins are putative endogenous natriuretic hormones. The role of each in facilitating natriuresis induced by intravenous saline infusion was examined in normal volunteers in relation to administration of carbidopa...
Articles
Clin Sci (Lond) (1997) 92 (3): 255–260.
Published: 01 March 1997
... of 0.25 pmol min −1 kg −1 (mean increment above control 3.9 pmol/l, P < 0.001), and tripled ( P < 0.001) with 0.5 pmol min −1 kg −1 . Plasma renin activity was inhibited by both doses (14.8%, P < 0.01, and 20%, P < 0.001, respectively). A significant natriuresis (56% increase in urine sodium...
Articles
Clin Sci (Lond) (1997) 92 (2): 159–165.
Published: 01 February 1997
... and the Medical Research Society 1997 cyclic GMP haemodynamics natriuresis ventricular pacing Clinical Science (1997) 92, 159-165 (Printed in Great Britain) I59 Comparative bioactivity of atrial and brain natriuretic peptides in an ovine model of heart failup \ \ Miriam Tessa RADEMAKER, Christopher...
Articles
Clin Sci (Lond) (1996) 91 (3): 283–291.
Published: 01 September 1996
... animals, SCH32615 induced reductions in mean arterial pressure and left atrial pressure and increases in haematocrit, plasma cGMP and endogenous creatinine clearance. However, only in heart failure did neutral endopeptidase inhibition induce a significant and marked natriuresis (> 10-fold increase...
Articles
Clin Sci (Lond) (1996) 91 (1): 3–16.
Published: 01 July 1996
...A. Mark Richards; M. Gary Nicholls; Lynley Lewis; John G. Lainchbury © 1996 The Biochemical Society and the Medical Research Society 1996 cyclic AMP heart failure hypertension natriuresis G-protein-linked receptors vasodilator peptides Clinical Science (1996) 91, 3-16 (Printed...
Articles
Clin Sci (Lond) (1994) 86 (6): 723–730.
Published: 01 June 1994
... in the physiological regulation of sodium balance. 13 12 1993 7 1 1994 © 1994 The Biochemical Society and the Medical Research Society 1994 atrial natriuretic peptide brain natriuretic peptide natriuresis natriuretic peptides pharmacokinetics Clinical Science (1994) 86, 723-730 (Printed...
Articles
Clin Sci (Lond) (1993) 85 (4): 471–477.
Published: 01 October 1993
... normally observed during immersion. 7 4 1993 10 6 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 head-out immersion kidney transplantation natriuresis renal innvervation Clinical Science (1993) 85, 4 7 1 4 7 (Printed in Great Britain) 47 I Natriuretic...
Articles
Clin Sci (Lond) (1993) 85 (2): 139–145.
Published: 01 August 1993
... expansion. diuresis natriuresis renal haemodynamics renal interstitial pressure sodium retention 7 4 1993 30 4 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 Clinical Science (1993) 85, 13W45 (Printed in Great Britain) Reduced renal papillary plasma...
Articles
Clin Sci (Lond) (1993) 85 (2): 147–156.
Published: 01 August 1993
... min −1 kg −1 . Pressor doses of angiotensin II also have a significant effect on the distal tubule in promoting sodium reabsorption. angiotensin II natriuresis tubular handling © 1993 The Biochemical Society and the Medical Research Society 1993 10 5 1993 17 5 1993 Clinical...
Articles
Clin Sci (Lond) (1993) 84 (5): 549–557.
Published: 01 May 1993
... 1 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 catecholamines dihydroxyphenylalanine dopamine natriuresis sympathetic nervous system Clinical Science (1993) 84, 54S557 (Printed in Great Britain) 549 Derivation of urinary dopamine from plasma di...
Articles
Clin Sci (Lond) (1993) 84 (2): 237–242.
Published: 01 February 1993
... natriuresis renal function sodium Clinical Science (1993) 84, 237-242 (Printed i n Great Britain) 237 Lithium clearance method and the renal response to lowdose dopamine in man: a randomized, controlled study Niels Vidiendal OLSEN*, Michael Hecht OLSENT, Niels FOGH-ANDERSENS, Bo FELDT-RASMUSSENg...
Articles
Clin Sci (Lond) (1992) 82 (2): 119–126.
Published: 01 February 1992
... concentration rose from 18.5 to 49.2 pmol/l in association with an immediate natriuresis (a rise of 49.1 μmol/min in the first 30 min, P <0.05; peaking at a 61% increase from baseline, P <0.01), diuresis (from 3.37 to 7.46 ml/min) and a threefold rise in urinary cyclic GMP excretion. 3. In response...
Articles
Clin Sci (Lond) (1991) 80 (3): 265–269.
Published: 01 March 1991
... natriuretic factor. 22 8 1990 18 10 1990 © 1991 The Biochemical Society and the Medical Research Society 1991 antihypertensive atrial natriuretic factor atriopeptidase inhibitor (±)-candoxatrilat natriuresis neutral endopeptidase (EC 3.4.24.11) Clinical Science (1991) 80, 265...
Articles
Clin Sci (Lond) (1990) 78 (5): 481–485.
Published: 01 May 1990
...S. C. Tam; L. S. Tang; C. K. Lai; M. G. Nicholls; R. Swaminathan 1. The increase in glomerular filtration rate after a protein meal is believed to be mediated by hormonal factors. Since natriuresis is often observed after a protein meal, it was postulated that the increase in glomerular filtration...
Articles
Clin Sci (Lond) (1990) 78 (4): 371–375.
Published: 01 April 1990
..., but the natriuresis during infusion of α-human atrial natriuretic peptide was attenuated. 3. Similar decreases in plasma renin activity with infusion of α-human atrial natriuretic peptide occurred on both days. 4. Administration of lithium may be associated with pharmacological effects and further work is required...
Articles
Clin Sci (Lond) (1990) 78 (4): 423–429.
Published: 01 April 1990
... Society 1990 denervation dopa dopamine natriuresis salt sodium Clinical Science (1990) 78,423-429 423 Increased spillover of dopa into arterial blood during dietary salt loading EHUD GROSSMAN', AARON HOFFMAN', PETER C. CHANG', HARRY R. KEISER' AND DAVID S. GOLDSTEIN' 'Hypertension-Endocrine...
Articles
Clin Sci (Lond) (1989) 77 (5): 479–484.
Published: 01 November 1989
... natriuresis and plasma aldosterone suppression, independently of the marked elevation of circulating atrial natriuretic factor, via a mechanism involving type 2 dopaminergic receptors. 21 3 1989 13 4 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 atrial...
Articles
Clin Sci (Lond) (1989) 77 (3): 281–285.
Published: 01 September 1989
... infusion on both visits. 4. Infusion of atrial natriuretic factor produced a small unsustained rise in urinary dopamine excretion. This increase in urinary dopamine excretion was blocked by carbidopa with no effect on the natriuresis. 5. Urinary guanosine 3′:5′-cyclic monophosphate excretion increased...
Articles
Clin Sci (Lond) (1989) 76 (5): 517–522.
Published: 01 May 1989
... 1988 29 9 1988 © 1989 The Biochemical Society and the Medical Research Society 1989 catecholamines dihydroxyphenylalanine dopamine kidney natriuresis sympathetic nervous system Clinical Science (1989) 76,517-522 517 Urinary excretion of dihydroxyphenylalanine and dopamine...
Articles
Clin Sci (Lond) (1988) 75 (5): 489–494.
Published: 01 November 1988
... Society 1970 atrial natriuretic factor guanosine 3′:5′-cyclic monophosphate kallikrein natriuresis saline Clinical Science (1988) 75,489-494 489 Urinary guanosine 3': 5'-cyclic monophosphate but not tissue kallikrein follows the plasma atrial natriuretic factor response to acute volume...
Articles
Clin Sci (Lond) (1988) 75 (5): 495–498.
Published: 01 November 1988
...) infusions have similar effects on glomerular filtration rate, natriuresis and kaliuresis, we decided to investigate the possibility that a protein meal could stimulate ANF activity. 2. We studied 10 normal volunteers who had a fixed protein and sodium intake for 7 days before the experiments. The subjects...
Articles
Clin Sci (Lond) (1988) 75 (5): 515–520.
Published: 01 November 1988
... be accounted for by uptake and decarboxylation of circulating endogenous dopa. 3. Plasma dopa is the main source of urinary DA. 9 3 1988 26 4 1988 © 1970 The Biochemical Society and the Medical Research Society 1970 catecholamines dopamine dopa natriuresis sympathetic nervous system...
Articles
Clin Sci (Lond) (1988) 75 (5): 455–462.
Published: 01 November 1988
... initially induced similar natriuresis and suppression of renin–angiotensin– aldosterone system activity in association with markedly disparate values of plasma ANF. Plasma ANF levels rose to two- and eight-fold placebo values with saline and ANF, respectively ( P < 0.001). Conversely, in the period after...
Articles
Clin Sci (Lond) (1988) 75 (4): 421–428.
Published: 01 October 1988
...A. J. Smit; S. Meijer; H. Wesseling; A. J. M. Donker; W. D. Reitsma 1. The effects of intravenous metoclopramide on baseline values and dopamine dose–response curves for renal haemodynamics and natriuresis were investigated in healthy volunteers and patients with renal disease. 2. Dopamine infusion...
Articles
Clin Sci (Lond) (1988) 75 (3): 271–276.
Published: 01 September 1988
.... This contrasted with the rise in filtration fraction after expansion in normoproteinaemia, where filtration fraction increased from 32 to 39% due to a rise in glomerular filtration rate. 4. After expansion, natriuresis rose to similar levels in normoproteinaemia (0.18 ±0.06 mmol/min) and hypoproteinaemia (0.20...
Articles
Clin Sci (Lond) (1988) 74 (6): 571–576.
Published: 01 June 1988
... between elevated ANP concentrations and natriuresis in this study indicates that a rise in ANP concentrations per se is not sufficient to produce a natriuresis. 3 11 1987 16 11 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 arginine vasopressin atrial...
Articles
Clin Sci (Lond) (1988) 74 (6): 659–663.
Published: 01 June 1988
... volume myocardial infarction natriuresis preload Clinical Science (1988) 74,659-663 659 Atrial natriuretic peptide and total exchangeable body sodium: relationships in rats with chronic myocardial infarction G. P. HODSMAN, R. W. HARRISON, E. SUMITHRAN* AND C. I. JOHNSTON University of Melbourne...
Articles
Clin Sci (Lond) (1988) 74 (4): 365–372.
Published: 01 April 1988
... renal excretion mainly via inhibition of angiotensin II and angiotensin III formation. 13 8 1987 15 9 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 angiotensin II blood pressure cilazapril diuresis Goldblatt hypertension natriuresis Clinical...
Articles
Clin Sci (Lond) (1987) 73 (4): 431–436.
Published: 01 October 1987
... sodium balance exceeded 220 mmol. 5. These results suggest that h-αANP may play a contributory role in natriuresis and diuresis after mineralocorticoid excess. 2 2 1987 11 5 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 atrial natriuretic polypeptide...
Articles
Clin Sci (Lond) (1987) 72 (4): 449–454.
Published: 01 April 1987
... diuresis frusemide kallikrein–kinin system natriuresis ClinicalScience( 1987) 12, 449-454 449 Amiloride inhibits the rise of urinary kallikrein excretion induced by frusemide administration in the rat . L. F. 0. O B I U AND M. MARIN-GSZ* Department of Physiology and Biochemistry, University of Ilorin...
Articles
Clin Sci (Lond) (1987) 72 (3): 305–312.
Published: 01 March 1987
...J. V. Anderson; J. Donckier; N. N. Payne; J. Beacham; J. D. H. Slater; Pr S. R. Bloom 1. The administration of exogenous atrial natriuretic peptide (ANP) causes a natriuresis and diuresis in man, but this has, to date, only been demonstrated at plasma ANP concentrations within the high pathological...
Articles
Clin Sci (Lond) (1987) 72 (2): 195–200.
Published: 01 February 1987
... and fractional sodium excretion. natriuresis sodium vasoactive intestinal peptide © 1970 The Biochemical Society and the Medical Research Society 1970 30 6 1986 20 8 1986 ClinicalScience(l987) 7 2 , 195-200 195 Vasoactive intestinal peptide: a direct renal natriuretic substance K...
Articles
Clin Sci (Lond) (1986) 71 (5): 497–503.
Published: 01 November 1986
...–kinin system natriuresis CIinicalScience(1986) 71, 497-503 497 Urinary kallikrein response to repeated frusemide injections in rats: effect of adrenalectomy and deoxycorticosterone acetate treatment L. F. 0. OBI= AND M. M A U - G R E Z * Department of Physiology and Biochemistry, University...
Articles
Clin Sci (Lond) (1986) 70 (5): 453–460.
Published: 01 May 1986
... excretion of water and sodium, but not potassium, increased after verapamil. However, the diuresis and natriuresis were less pronounced than those seen in the non-clipped kidney of hypertensive rats. 5. There was a proportionate increase in osmolar clearance and free water reabsorption rate in the non...
Articles
Clin Sci (Lond) (1986) 70 (5): 409–416.
Published: 01 May 1986
... by indomethacin. 7. The findings show that infusions of AVP, resulting in plasma concentrations in the physiological range, evoke a maximal antidiuretic response, which is accompanied by natriuresis. Significant inhibition of urinary prostaglandin excretion by indomethacin is accompanied by both enhancement...
Articles
Clin Sci (Lond) (1986) 70 (5): 523–526.
Published: 01 May 1986
...P. Coruzzi; A. Biggi; L. Musiari; C. Ravanetti; P. P. Vescovi; A. Novarini 1. Natriuresis was studied during water immersion in eight normal subjects either in the absence or in the presence of dopamine blockade by domperidone. 2. Creatinine clearance showed no significant changes; urine flow...
Articles
Clin Sci (Lond) (1986) 70 (5): 507–512.
Published: 01 May 1986
... but that it may also act as a modulator of a related endocrine system. 14 10 1985 10 12 1985 © 1986 The Biochemical Society and the Medical Research Society 1986 aldosterone angiotensin II atrial natriuretic peptide natriuresis natriuretic factor renin-angiotensin system Clinical...
Articles
Clin Sci (Lond) (1985) 69 (4): 493–496.
Published: 01 October 1985
...J. P. O'hare; M. Watson; M. D. Penney; D. Hampton; J. M. Roland; R. J. M. Corrall 1. In 10 normal subjects water immersion to the neck at 35°C produced a highly significant natriuresis and diuresis. 2. Urinary prostaglandin E levels did not change significantly throughout immersion. 3. During...
Articles
Clin Sci (Lond) (1985) 69 (2): 207–214.
Published: 01 August 1985
... dopamine γ-l-glutamyl-l-dopa kidney natriuresis plasma renin activity renal haemodynamics clinical Science (1985) 69, 207-214 207 y -L-Glutamyl-L-dopa is a dopamine pro-drug, relatively specific for the kidney in normal subjects D. P . WORTH, J. N. HARVEY, J. BROWN A N D M . R. LEE* Department...
Articles
Clin Sci (Lond) (1985) 68 (4): 373–377.
Published: 01 April 1985
... the juxtaglomerular apparatus is most numerous. 2. In the isolated perfused rat kidney, NPY caused a prompt dose-dependent increase in perfusion pressure and reduction in flow, with only a small fall in glomerular filtration rate (GFR). In spite of the reduced renal perfusion, a dose-dependent natriuresis...
Articles
Clin Sci (Lond) (1984) 67 (4): 403–405.
Published: 01 October 1984
... system. 14 12 1983 28 3 1984 © 1984 The Biochemical Society and the Medical Research Society 1984 diuresis frusemide natriuresis ouabain rat atrial peptides Clinical Science (1984) 67, 403-4G5 403 Atrial natriuretic factor: sodium transport in human erythrocytes NICK C...
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Clin Sci (Lond) (1984) 67 (3): 353–358.
Published: 01 September 1984
... natriuresis plasma aldosterone plasma noradrenaline plasma renin activity plasma volume vasopressin Clinical Science (1984) 67, 353-358 353 The effects of a chronic infusion of arginine vasopressin in salt-restricted, water-deprived man P. J . T. D R E W , J . N. B A R N E S , J . M . P. H O L L Y...
Articles
Clin Sci (Lond) (1984) 66 (5): 621–624.
Published: 01 May 1984
... and is associated with the appearance of a humoral factor which blocks prostacyclin byosynthesis. 31 10 1983 9 11 1983 © 1984 The Biochemical Society and the Medical Research Society 1984 endogenous prostaglandin inhibitor natriuresis sodium-enriched cerebrospinal fluid Clinical Science...