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Keywords: mtDNA
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Clin Sci (Lond) (2022) 136 (5): 345–360.
Published: 09 March 2022
... on preclinical studies because renal biopsies are not routinely performed in many patients with CKD. Previous studies have shown that urinary mitochondrial DNA (mtDNA) copy numbers may serve as non-invasive biomarkers of renal mitochondrial dysfunction. Emerging data also suggest that CKD is associated...
Clin Sci (Lond) (2020) 134 (7): 889–905.
Published: 17 April 2020
... IPF idiopathic pulmonary fibrosis LF lung fibroblast SASP senescence-associated secretory phenotype siRNA silencing RNA TLR toll-like receptor cGAMP GMP-AMP synthase (cGAS) mtDNA pulmonary fibrosis senescence References 1. Murtha L.A...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (6): 393–407.
Published: 04 February 2016
... 20 11 2015 © 2016 Authors; published by Portland Press Limited 2016 cytochrome c oxidase genetic diseases mitochondrial diseases mtDNA Cytochrome c oxidase (COX; EC is the unique terminal oxidase of the mitochondrial respiratory chain (RC) in mammals ( Figure 1...