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Keywords: mitofusin-1
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In Collection
Clinical and translational research highlights
Lara Matilla, Jaime Ibarrola, Vanessa Arrieta, Amaia Garcia-Peña, Ernesto Martinez-Martinez, Rafael Sádaba, Virginia Alvarez, Adela Navarro, Amaya Fernández-Celis, Alicia Gainza, Enrique Santamaría, Joaquín Fernández-Irigoyen, Antoni Bayes-Genis, Patrick Rossignol, Natalia López-Andrés
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (14): 1537–1548.
Published: 17 July 2019
...: Using proteomics and immunodetection approaches, we have identified that sST2 down-regulated mitofusin-1 (MFN-1), a protein involved in mitochondrial fusion, in human cardiac fibroblasts. In parallel, sST2 increased nitrotyrosine, protein oxidation and peroxide production. Moreover, sST2 enhanced...
Includes: Supplementary data
