... microparticles placenta pregnancy Human pregnancy is characterized by systemic alterations to the cardiovascular system, including a 30–50% increase in cardiac output and reduced peripheral vascular resistance, and immunomodulation to facilitate the tolerance of the semi-allogenic fetus [ 1...

... and the Biochemical Society under a transformative agreement with CAUL. glucose homeostasis insulin resistance microparticles pancreatic beta cell Gestational diabetes mellitus (GDM) is defined as glucose intolerance with onset during pregnancy [ 1 ]. The prevalence of GDM worldwide is increasing...

..., leading to endothelial dysfunction. In the present study, we investigated the associations between habitual sodium intake and RAAS blockade on endothelial function by measuring circulating microparticles (MPs) in individuals with T2D. Methods: We conducted a prospective, cross-sectional study in 74...

... cycles/h) stimulated the ER stress response and microparticle(s) (MP) production from both SMC and endothelial cell(s) (EC) in a time-dependent manner. Treatment of EC with isolated MP led to anoikis, which was determined by measuring the fluorescence of the ethidium homodimer (EthD-1) and Calcein AM...

...Satoru Eguchi; Victor Rizzo In addition to organelle-to-organelle communication within the cell, autocrine, paracrine and even endocrine mechanisms can be conveyed through cell-derived vesicles such as microparticles and exosomes. These organelles carry miRNAs, hormonal factors and cell surface...

...Lisa Ayers; Rienk Nieuwland; Malcolm Kohler; Nicolle Kraenkel; Berne Ferry; Paul Leeson Interest in cell-derived microvesicles (or microparticles) within cardiovascular diagnostics and therapeutics is rapidly growing. Microvesicles are often measured in the circulation at a single time point...

...Jong-Shyan Wang; Ya-Lun Chang; Yi-Ching Chen; Hsing-Hua Tsai; Tieh-Cheng Fu Exercise and hypoxia paradoxically modulate vascular thrombotic risks. The shedding of procoagulant-rich microparticles from monocytes may accelerate the pathogenesis of atherothrombosis. The present study explores...

... and the Medical Research Society 1976 bone blood flow microparticles Clinical Science and Molecular Medicine (1976) 51, 403-406. Bone blood flow in the rat determined by the uptake of radioactive particles P. TOTHILL* A N D J. ST C. McCORMICKt * Department of Medical Physics, Royal Infirmary, Edinburgh...

...R. Wootton 1. The uptake of an intra-arterial injection of 18 F was compared with the uptake of a simultaneous injection of 51 Cr-labelled microparticles in rabbit bone. 2. The mean single-passage extraction ratio of 18 F was 102% (sem 11%, n = 9) in the femur and 119% (sem 9%, n = 10) in the tibia...