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Keywords: microbiome
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Clin Sci (Lond) (2022) 136 (6): 425–429.
Published: 25 March 2022
... to the bidirectional relationship between gut microbiota and the liver. Cirrhosis negatively affects host–microbiome interactions; in return, disruption of gut microbiota (dysbiosis) appears to contribute to the progression of chronic liver disease [ 7 ]. Efforts to restore the composition and function of gut...
Clin Sci (Lond) (2020) 134 (23): 3159–3174.
Published: 09 December 2020
... understood at present. Herein, we used a mouse (8 weeks) OA model of destabilization of the medial meniscus (DMM) and gut microbiome dysbiosis induced by antibiotic treatment with ampicillin and neomycin for 8 weeks. The results show that antibiotic-induced intestinal microbiota dysbiosis reduced the serum...
Includes: Supplementary data
Clin Sci (Lond) (2018) 132 (22): 2387–2389.
Published: 19 November 2018
...Michael Weis The gut microbiome functions like an endocrine organ, generating enzymes and bioactive metabolites, which affect host physiology. In addition metabolism-independent processes like impaired intestinal barrier function may result in bacterial translocation and an increased inflammation...
Clin Sci (Lond) (2018) 132 (6): 701–718.
Published: 30 March 2018
...Seungbum Kim; Ruby Goel; Ashok Kumar; Yanfei Qi; Gil Lobaton; Koji Hosaka; Mohammed Mohammed; Eileen M. Handberg; Elaine M. Richards; Carl J. Pepine; Mohan K. Raizada Recent evidence indicates a link between gut pathology and microbiome with hypertension (HTN) in animal models. However, whether...
Includes: Supplementary data
Clin Sci (Lond) (2018) 132 (5): 509–522.
Published: 09 March 2018
...Wei Ling Lau; Javad Savoj; Michael B. Nakata; Nosratola D. Vaziri In chronic kidney disease (CKD), influx of urea and other retained toxins exerts a change in the gut microbiome. There is decreased number of beneficial bacteria that produce short-chain fatty acids, an essential nutrient...
Clin Sci (Lond) (2018) 132 (5): 523–542.
Published: 09 March 2018
... and endocrine symptoms. Several microbiome studies have described alterations in the bacterial component of the microbiome (dysbiosis) consistent with a possible role in disease development. However, in focusing on the bacterial components of the microbiome, these studies have neglected the viral constituent...
Clin Sci (Lond) (2018) 132 (2): 199–212.
Published: 19 January 2018
... Limited on behalf of the Biochemical Society 2018 alcohol dependence brain gut barrier inflammation liver disease microbiome Alcohol abuse is a major public health problem worldwide causing a wide range of preventable morbidity and mortality [ 1 – 3 ]. Subjects drinking up to two drinks...
Clin Sci (Lond) (2015) 129 (12): 1083–1096.
Published: 13 October 2015
... contributor to obesity, which is the largest risk factor for T2D. The microbiota can be rapidly altered due to changes in diet with associated effects on host metabolism. In response to a 5-day diet swap, rapid changes in the composition of the faecal microbiome occurred in humans who were fed on diets...