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Keywords: microbiome
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Clin Sci (Lond) (2023) 137 (8): 645–662.
Published: 21 April 2023
... that develops independently, and its presence could be recognized by the detection, in blood, of lipopolysaccharides and (1→3)-β-D-glucan (major components of gut microbiota). Gut-dysbiosis is the consequence of a reduction in some bacterial species in the gut microbiome, as a consequence of intestinal mucosal...
Clin Sci (Lond) (2022) 136 (22): 1683–1690.
Published: 23 November 2022
...Fergus Shanahan; Tarini S. Ghosh; Michael G. Molloy; Paul W. O’Toole The microbiome contributes to human development and maturation, and is essential for maintenance of health and prevention of disease. While the human genome encodes one’s identity, the microbiome – also individually unique...
Clin Sci (Lond) (2022) 136 (6): 425–429.
Published: 25 March 2022
... of the Biochemical Society 2022 cirrhosis microbiome portal hypertension Sinusoidal portal hypertension (PH) is the major cause of morbidity and mortality in cirrhosis. While the pathophysiology through which PH develops is complex, changes in portal vein pressure can be expressed as a function...
Clin Sci (Lond) (2020) 134 (23): 3159–3174.
Published: 09 December 2020
... understood at present. Herein, we used a mouse (8 weeks) OA model of destabilization of the medial meniscus (DMM) and gut microbiome dysbiosis induced by antibiotic treatment with ampicillin and neomycin for 8 weeks. The results show that antibiotic-induced intestinal microbiota dysbiosis reduced the serum...
Includes: Supplementary data
Clin Sci (Lond) (2018) 132 (22): 2387–2389.
Published: 19 November 2018
...Michael Weis The gut microbiome functions like an endocrine organ, generating enzymes and bioactive metabolites, which affect host physiology. In addition metabolism-independent processes like impaired intestinal barrier function may result in bacterial translocation and an increased inflammation...
Clin Sci (Lond) (2018) 132 (5): 509–522.
Published: 09 March 2018
...Wei Ling Lau; Javad Savoj; Michael B. Nakata; Nosratola D. Vaziri In chronic kidney disease (CKD), influx of urea and other retained toxins exerts a change in the gut microbiome. There is decreased number of beneficial bacteria that produce short-chain fatty acids, an essential nutrient...
Clin Sci (Lond) (2018) 132 (5): 523–542.
Published: 09 March 2018
... and endocrine symptoms. Several microbiome studies have described alterations in the bacterial component of the microbiome (dysbiosis) consistent with a possible role in disease development. However, in focusing on the bacterial components of the microbiome, these studies have neglected the viral constituent...
Clin Sci (Lond) (2018) 132 (2): 199–212.
Published: 19 January 2018
... Limited on behalf of the Biochemical Society 2018 alcohol dependence brain gut barrier inflammation liver disease microbiome Alcohol abuse is a major public health problem worldwide causing a wide range of preventable morbidity and mortality [ 1 – 3 ]. Subjects drinking up to two drinks...
Clin Sci (Lond) (2015) 129 (12): 1083–1096.
Published: 13 October 2015
... 2015 25 8 2015 © 2015 Authors; published by Portland Press Limited 2015 antibiotics insulin resistance glucose metabolic inflammation microbiome Bacteria inhabit many niches, including multicellular animals. The assemblage of a bacterial community is termed the microbiota...