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Keywords: microRNA (miRNA)
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Clin Sci (Lond) (2017) 131 (5): 411–423.
Published: 17 February 2017
... 1 2017 © 2017 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2017 diabetic nephropathy kidney fibrosis mesangial cells microRNA (miRNA) transforming growth factor-β (TGF-β1) • Diabetic nephropathy (DN) is the leading cause...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (3): 181–195.
Published: 05 January 2017
... of 3D CAVD models, miRNA-based therapeutics and controlled drug-delivery strategies. aortic valve calcification 3D model drug delivery microRNA (miRNA) • Employing human 3D in vitro models of CAVD for identifying the underlying mechanisms and potential targets, and for drug...
Clin Sci (Lond) (2015) 128 (3): 153–180.
Published: 03 October 2014
...Monica Logan; Shannon M. Hawkins microRNAs (miRNAs) are small RNA molecules that represent the top of the pyramid of many tumorigenesis cascade pathways as they have the ability to affect multiple, intricate, and still undiscovered downstream targets. Understanding how miRNA molecules serve...
Clin Sci (Lond) (2014) 126 (3): 183–194.
Published: 01 October 2013
... Biochemical Society 2014 cardiovascular disease diabetes dyslipidaemia hypertension microRNA (miRNA) miRNAs (microRNAs) are short (~19–25 nucleotides in length) single-stranded non-encoding RNAs that are well conserved in eukaryotic organisms [ 1 , 2 ]. By base pairing with complementary...
Clin Sci (Lond) (2014) 126 (2): 95–110.
Published: 13 September 2013
..., a novel class of non-coding RNA, microRNA (miRNA), have emerged as being important regulators of numerous biological functions. Among these functions are basic maintenance of cell signalling and tissue architecture. Disruption of miRNA levels can contribute not only to the development of the chronic...
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... diagnosis hypertension kidney microRNA (miRNA) therapy translational research miRNAs (microRNAs) are endogenously produced non-coding RNA molecules approximately 22 nucleotides long that play a ubiquitous and important role in regulating protein expression ( Figure 1 A). miRNAs, and non-coding...
Clin Sci (Lond) (2010) 119 (8): 335–343.
Published: 06 July 2010
... in cardiovascular disease. coronary artery disease (CAD) gene expression microRNA (miRNA) mitochondrion oxidative phosphorylation rehabilitation programme CAD (coronary artery disease) is caused by multiple genetic and environmental factors and the interaction between them. Microarray analysis...
Includes: Supplementary data