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Keywords: methylation
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Articles
Clin Sci (Lond) (2020) 134 (15): 2037–2051.
Published: 07 August 2020
...Chunyun Zhang; Shougang Zhuang The methylation of arginine residues by protein arginine methyltransferases (PRMTs) is a crucial post-translational modification for many biological processes, including DNA repair, RNA processing, and transduction of intra- and extracellular signaling. Previous...
Articles
Clin Sci (Lond) (2020) 134 (2): 261–271.
Published: 29 January 2020
.... Furthermore, we demonstrate that CD48 expression is regulated by methylation and that a hypomethylating agent can increase the CD48 expression, which increases the NK cells killing in vitro . Finally, we show that CD48 high expression can reverse the AML immune evasion and activate NK cells function in vivo...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (9): 1085–1096.
Published: 09 May 2019
...Xue-liang Zhou; Zhi-bo Liu; Rong-rong Zhu; Huang Huang; Qi-rong Xu; Hua Xu; Liang Zeng; Yun-yun Li; Cha-hua Huang; Qi-cai Wu; Ji-chun Liu Nuclear receptor binding SET domain 2 (NSD2)-mediated metabolic reprogramming has been demonstrated to regulate oncogenesis via catalyzing the methylation...
Articles
Clin Sci (Lond) (2017) 131 (7): 583–594.
Published: 17 March 2017
.... The mechanism of CAE remains unclear, and its treatment is limited. Previous studies have shown that risk factors for CAE were related to changes in DNA methylation. However, no systematic investigation of methylation profiles has been performed. Therefore, we compared methylation profiles between 12 CAE...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2016) 130 (13): 1051–1063.
Published: 23 May 2016
... for muscle metabolic processes. Substantial evidence is emerging that highlights the importance of epigenetic mechanisms in this process. This review will examine the importance of epigenetics in the regulation of muscle metabolism, with a particular emphasis on DNA methylation and histone acetylation...