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Keywords: mesangial cells
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Clin Sci (Lond) (2019) 133 (15): 1721–1744.
Published: 05 August 2019
... of mycophenolate or rapamycin on kidney fibrosis in LN has not been investigated. We investigated the effects of mycophenolate and rapamycin in New Zealand Black and White first generation (NZB/W F1) murine LN and human mesangial cells (HMCs), focusing on mechanisms leading to kidney fibrosis. Treatment of mice...
Clin Sci (Lond) (2019) 133 (12): 1321–1339.
Published: 20 June 2019
...-3β inflammation lncRNA mesangial cells pathogenesis podocytes renal tubular cells therapies Currently, clinical management of DKD mainly focuses on controlling glycemic levels, normalizing blood pressures and blocking the renin–angiotensin–aldosterone system (RAAS). Tight glycemic control...
Clin Sci (Lond) (2017) 131 (5): 411–423.
Published: 17 February 2017
... (STZ)-induced diabetic mice at 18 weeks or in unilateral ureteral obstruction (UUO) mice at 7 days. miR-378 transfection of proximal tubular epithelial cells, NRK52E and mesangial cells was assessed with/without endogenous miR-378 knockdown using the locked nucleic acid (LNA) inhibitor. NRK52E cells...
Includes: Supplementary data
Clin Sci (Lond) (2002) 103 (s2002): 132S–136S.
Published: 01 September 2002
...Andrey SOROKIN; Marco FOSCHI; Michael J. DUNN The molecular mechanisms of endothelin (ET)-dependent activation of extracellular signal-regulated kinase (ERK)and p38 mitogen-activated protein (MAP) kinase were studied in rat and human renal glomerular mesangial cells. ET-1 induced a rapid...
Clin Sci (Lond) (1993) 85 (6): 747–751.
Published: 01 December 1993
...R. J. D'Souza; H. M. Phillips; P. W. Jones; R. C. Strange; G. M. Aber 1. This study examined the influence of H 2 O 2 , interleukin-6 and platelet-derived growth factor on the proliferation of rat mesangial cells. Mesangial cells were exposed to either a single pulse or three daily pulses of H 2 O...