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Keywords: liver X receptor
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Clin Sci (Lond) (2018) 132 (14): 1509–1512.
Published: 23 July 2018
... the greater severity of atherosclerosis. Interestingly, foam cell formation was closely associated with the expression of cholesterol transporters (ABCA1 and ACBG1) that facilitate cholesterol efflux. Liver X receptor (LXR)-β is a key modulator of cholesterol transporter expression and formed direct...
Clin Sci (Lond) (2013) 124 (8): 509–515.
Published: 08 January 2013
...)-dependent generation of oxysterol ligands for LXR (liver X receptor) transcription factors that regulate the expression of genes encoding proteins in the cholesterol efflux pathway, such as ABC transporters (ATP-binding cassette transporters) ABCA1 and ABCG1. These transporters transfer cholesterol...