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1-32 of 32
Keywords: lithium
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 96 (1): 5–15.
Published: 01 January 1999
... heart failure (27 ; μ mol/min) than in control subjects (190 ; μ mol/min). Urinary flow rate did not change. The lithium clearance technique was used to evaluate the segmental tubular function; the distal fractional reabsorption of sodium decreased significantly less in congestive heart failure (DFR Na...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (1): 51–58.
Published: 01 January 1997
... insulin for 4 h (50 m-units h −1 kg −1 ) on fractional renal sodium and urate excretion in 13 healthy subjects, using the euglycaemic clamp and lithium clearance technique, and performed a control experiment in eight of the subjects. 2. Insulin caused a decline in both fractional renal sodium excretion...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (3): 351–358.
Published: 01 March 1995
... (Na + ) and lithium (Li + ) in rats by means of free-flow micropuncture at the late proximal tubule and the early distal tubule. 2. Endogenous angiotensin II was suppressed by pretreament with enalapril. Compared with a control group, angiotensin II increased mean arterial pressure by 15 mmHg...
Articles
Niels Vidiendal Olsen, Michael Hecht Olsen, Niels Fogh-Andersen, Bo Feldt-Rasmussen, Annelise Kamper, Inger Plum, Svend Strandgaard, Paul Peter Leyssac
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (2): 237–242.
Published: 01 February 1993
...Niels Vidiendal Olsen; Michael Hecht Olsen; Niels Fogh-Andersen; Bo Feldt-Rasmussen; Annelise Kamper; Inger Plum; Svend Strandgaard; Paul Peter Leyssac 1. The effect of a single dose of lithium on renal function before and during intravenous infusion of dopamine (3 μg min −1 kg −1...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (5): 543–549.
Published: 01 May 1992
...D. W. Eadington; S. Freestone; C. J. Waugh; C. P. Swainson; M. R. Lee 1. Renal and systemic responses to infusion of angiotensin II (1.25 and 2.5 ng min −1 kg −1 body weight) were examined in ten normal males 12 h after single doses of 750 mg of lithium carbonate, 250 mg of lithium carbonate ( n...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (4): 341–352.
Published: 01 April 1992
...P. A. Rutherford; T. H. Thomas; R. Wilkinson Clinical Science (1992) 82, 341-352 (Printed in Great Britain) Editorial Review 34 I Erythrocyte sodium-lithium countertransport: clinically useful, pathophysiologically instructive or just phenomenology ? P. A. RUTHERFORD, T. H. THOMAS and R. WlLKlNSON...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (4): 407–412.
Published: 01 April 1992
... anticipated that lithium, through its effects on cell signal transduction and ion-transport pathways, would be likely to protect the airways against constrictor stimuli. 2. We carried out a randomized, double-blind study of lithium carbonate in asthmatic patients. 3. After a 1 week run-in period, 27 patients...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (3): 291–299.
Published: 01 March 1992
...Peter A. Rutherford; Trevor H. Thomas; Susan J. Carr; Roy Taylor; Robert Wllklnson 1. Increased erythrocyte sodium-lithium countertransport activity has been reported to be associated with nephropathy in type 1 diabetes and linked to a family history of essential hypertension. 2. This study aimed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1991) 81 (6): 809–814.
Published: 01 December 1991
...Jørgen Søberg Petersen; Michael Shalmi; Martin Bak; Niels Lomholt; Sten Christensen 1. The effects of acute systemic α 1 -anoceptor blockade by doxazosin on glomerular filtration rate, urine flow, sodium clearance and lithium clearance were investigated in acutely prepared conscious rats. 2...
Articles
D. G. Shirley, D. R. J. Singer, G. A. Sagnella, M. G. Buckley, M. A. Miller, N. D. Markandu, G. A. MacGregor
Journal:
Clinical Science
Clin Sci (Lond) (1991) 81 (1): 59–63.
Published: 01 July 1991
...D. G. Shirley; D. R. J. Singer; G. A. Sagnella; M. G. Buckley; M. A. Miller; N. D. Markandu; G. A. MacGregor 1. The possible natriuretic and kaliuretic effects of a single dose of lithium, as used in lithium clearance studies, were investigated in 15 healthy subjects on fixed sodium (100 mmol/24 h...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1991) 80 (5): 481–488.
Published: 01 May 1991
... and the natriuresis induced by head-out water immersion were similar to those in control studies. 4. During the 200 mmol of sodium/day diet, indomethacin had no effect on baseline sodium excretion, nor on the natriuretic effect of head-out water immersion. 5. Head-out water immersion decreased tubular lithium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (2): 123–129.
Published: 01 August 1990
... a significant change in renal plasma flow. 3. After captopril therapy, despite the increase in renal plasma flow, there was no significant change in proximal sodium reabsorption (as estimated from fractional lithium reabsorption), urine volume or urine osmolality. 4. The decrease in glomerular filtration rate...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (1): 23–27.
Published: 01 July 1990
... intratubular pH using Sb microelectrodes during stopped-flow microperfusion with Krebs-Ringer bicarbonate (30 mmol/l) buffer. Four groups of male Wistar rats were utilized in this study: control, control plus lithium (C + Li + ; one intraperitoneal injection of LiCl of 4 mmol l −1 day −1 kg −1 for 4 days...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (4): 371–375.
Published: 01 April 1990
...S. Freestone; R. F. Jeffrey; C. V. Bonner; M. R. Lee 1. α-Human atrial natriuretic peptide (7.5 pmol min −1 kg −1 ) was infused intravenously into eight healthy men after pretreatment with lithium carbonate (750 mg) or placebo. 2. Baseline sodium excretion was significantly increased after lithium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 76 (4): 397–402.
Published: 01 April 1989
...A. J. Wood; A. Viswalingam; P. Glue; J. K. Aronson; D. G. Grahame-Smith 1. We have measured cation transport in vivo in seven healthy volunteers under control conditions and after they had taken lithium carbonate for 21 days in doses which maintained the serum lithium concentration in the range 0.6...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 76 (3): 335–341.
Published: 01 March 1989
...J. D. Firth; A. E. G. Raine; J. G. G. Ledingham 1. Isolated kidneys taken from spontaneously hypertensive rats (SHR) and normotensive Wistar–Kyoto rats (WKY) were perfused over a range of perfusion pressures. 2. Lithium clearance was used as an index of proximal tubule sodium handling. 3. When...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (4): 403–410.
Published: 01 October 1988
...L. R. Solomon; J. C. Atherton; H. Bobinski; V. Hillier; R. Green 1. The effects of the infusion of a low dose (2 pmol min −1 kg −1 for 3 h) of human atrial natriuretic peptide (hANP) were studied in seven healthy volunteers undergoing a water diuresis. Lithium clearance was used to monitor proximal...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (2): 151–157.
Published: 01 August 1988
... contributory factor in these responses to feeding. 3. Absolute delivery of sodium and water out of the proximal tubules (assessed by the lithium clearance method) was higher after both meals than while fasting; fractional lithium clearance was higher after the low protein meal than the high protein meal...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (6): 645–651.
Published: 01 December 1987
...J. C. Atherton; R. Green; S. Hughes; V. McFall; J. A. Sharples; L. R. Solomon; L. Wilson 1. The effects of amiloride and frusemide on lithium clearance were studied during changes in dietary sodium chloride intake and during infusion of 0.9% NaCl in normal human volunteers. 2. Lithium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (2): 201–208.
Published: 01 February 1987
... in the upright posture on a high than it was on a medium or low salt diet. On the medium and high but not on the low salt diet the concentration increased significantly on adoption of the supine posture. 3. Creatinine, sodium, lithium and fractional lithium clearances, fractional distal sodium excretion...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (1): 95–102.
Published: 01 January 1987
...C. P. Sanchez-Castillo; S. Warrender; T. P. Whitehead; W. P. T. James 1. An epidemiological study was conducted in the market town of March, Cambridgeshire, to assess the quantitative importance of cooking and table salt to total dietary salt intake by the use of a fused mixture of lithium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (1): 81–86.
Published: 01 January 1987
...C. P. Sanchez-Castillo; J. Seidell; W. P. T. James 1. Lithium was investigated for its possible use as a marker for identifying the various sources of NaCl in the diet. Micromolar concentrations of lithium can be detected in various vegetables, tap water and also in urine specimens of adult...
Articles
A test of the validity of the lithium-marker technique for monitoring dietary sources of salt in man
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (1): 87–94.
Published: 01 January 1987
...C. P. Sanchez-Castillo; W. J. Branch; W. P. T. James 1. A lithium-tagged salt for assessing the sources of salt in the human diet was prepared by fusing lithium carbonate and sodium chloride at 900°C followed by grinding and sieving the fused salts to a defined grain size; magnesium carbonate...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (5): 557–559.
Published: 01 May 1984
...D. G. Waller; J. D. M. Albano; J. G. B. Millar; A. Polak 1. Inhibition of adenylate cyclase has been proposed as a mechanism for hypothyroidism and nephrogenic diabetes insipidus occurring during lithium treatment, but these disorders are rarely found in the same patients. 2. We have measured...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (6): 549–554.
Published: 01 December 1982
... taking lithium (the lithium group), seven manic-depressive patients taking other psychotropic drugs but not lithium (the other drug group), seven healthy subjects (the control group) and three lithium-treated patients with polyuria (the polyuric lithium group). 2. The lithium group had a resistance...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 57s–59s.
Published: 01 October 1982
... transport systems alone. cotransport countertransport erythrocyte lithium sodium © 1982 The Biochemical Society and the Medical Research Society 1982 Clinical Science (1982) 63,5ls-S9s 57s Erythrocyte membrane transport systems as possible markers for essential hypertension D. C U S I . C . B...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (6): 793–795.
Published: 01 December 1981
...M. D. Penney; R. P. Hullin; D. P. Srinivasan; D. B. Morgan 1. Arginine vasopressin (AVP) was measured in morning samples of urine from 58 patients treated with lithium for unipolar or bipolar affective disorders and from 25 healthy control subjects. 2. the AVP excretion rate was increased...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 13s–15s.
Published: 01 December 1981
...M. Canali; L. Borghi; E. Sani; A. Curti; A. Montanari; A. Novarini; A. Borghetti 1. Erythrocyte lithium—sodium counter-transport was measured in 46 normotensive healthy controls without family history of hypertension, 15 subjects with essential hypertension, but without evidence of family history...
Articles
M. Trevisan, R. Cooper, D. Ostrow, W. Miller, S. Sparks, Y. Leonas, A. Allen, M. Steinhauer, J. Stamler
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 29s–32s.
Published: 01 December 1981
...M. Trevisan; R. Cooper; D. Ostrow; W. Miller; S. Sparks; Y. Leonas; A. Allen; M. Steinhauer; J. Stamler 1. There was a significant positive relationship between sodium-stimulated lithium efflux and systolic blood pressure ( r = 0.512) in erythrocytes of black school children. Weight was also...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 33s–36s.
Published: 01 December 1981
...D. Cusi; C. Barlassina; M. Ferrandi; P. Palazzi; E. Celega; G. Bianchi 1. The maximal rate of activity of sodium extrusion by the sodium pump, Na + —K + outward cotransport, passive permeability to sodium and potassium, Na + —Li + countertransport, and passive permeability to lithium were measured...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (1): 29–39.
Published: 01 July 1980
... with pool B) appeared to be of relatively little significance in transepithelial movement of potassium in the human distal colon. 3. Sodium and chloride movements were unaffected when lithium was present in the luminal solution, but the potassium secretion rate was nearly trebled due to increased plasma...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (3): 287–296.
Published: 01 September 1976
..., or by the luminal sodium concentration or by the osmolality of the luminal solution. 4. Potassium secretion rate was increased by partial substitution of other cations for sodium, in the descending order Li > NH 4 > Rb > Na. Potassium concentration increased on average to over 80 mmol/l when lithium...
