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Keywords: leflunomide
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Clin Sci (Lond) (2018) 132 (10): 1069–1073.
Published: 25 May 2018
..., issue 6, 685-699), Ma et al. describe that the anti-inflammatory drug leflunomide markedly antagonized CH, dysfunction, and fibrosis induced by aortic banding or angiotensin-II in mice or by agonists in cultured cells. Unexpectedly, this occurred not via anti-inflammatory mechanisms but rather via...
Clin Sci (Lond) (2018) 132 (6): 685–699.
Published: 30 March 2018
... of leflunomide, has been reported to have powerful anti-inflammatory and T cell-inhibiting properties. However, the effect of A77 1726 on cardiac hypertrophy remains completely unknown. Herein, we found that A77 1726 treatment attenuated pressure overload or angiotensin II (Ang II)-induced cardiac hypertrophy...
Includes: Supplementary data