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Keywords: ischaemia/reperfusion injury
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Clin Sci (Lond) (2016) 130 (10): 801–812.
Published: 01 April 2016
...Yan Wang; Haobo Li; Huansen Huang; Shiming Liu; Xiaowen Mao; Sheng Wang; Stanley Sau-ching Wong; Zhengyuan Xia; Michael G. Irwin Isoflurane postconditioning (IsoPostC) attenuates myocardial ischaemia/reperfusion injury (IRI). Signal transducer and activator of transcription-3 (STAT3) is critical...
Includes: Supplementary data
Clin Sci (Lond) (2015) 128 (10): 679–693.
Published: 27 February 2015
... damage in a variety of immune-mediated disorders. However, its role in myocardial ischaemia/reperfusion injury (MIRI) remains unknown. The purpose of the present study was to determine whether Tregs exert a beneficial effect on mouse MIRI. We examined the role of Tregs in murine MIRI by depletion using...
Includes: Supplementary data
Clin Sci (Lond) (2014) 127 (6): 405–413.
Published: 29 May 2014
... by inducing the PHR (portal hypertensive response) via B 2 R, whereas DABK (des-Arg 9 -BK), a B 1 R agonist, does not elicit the response. During IRI (ischaemia/reperfusion injury), important changes occur in the microcirculation, and cell death by necrosis and apoptosis is involved in poor graft function...
Clin Sci (Lond) (2010) 119 (2): 87–95.
Published: 20 April 2010
... with myocardial infarct size. To verify further the relationship between myocardial size and miR-1 level, an IP (ischaemic preconditioning) model was used. The results showed that IP significantly reduced circulating miR-1 levels and myocardial infract size induced by I/R (ischaemia/reperfusion) injury. Finally...
Clin Sci (Lond) (2010) 118 (12): 691–705.
Published: 30 March 2010
...: Professor Derek A. Mann (email derek.mann@newcastle.ac.uk ). 3 11 2009 6 1 2010 2 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 fibrosis hepatocellular carcinoma ischaemia/reperfusion injury non-alcoholic fatty liver disease (NAFLD) nuclear factor...
Clin Sci (Lond) (2010) 118 (4): 259–267.
Published: 09 November 2009
... pathophysiological mechanisms remain unclear. The FSL (Flinders Sensitive Line) rat is a genetic animal model of depression exhibiting features similar to those of depressed individuals. The aim of the present study was to compare the myocardial responsiveness to I/R (ischaemia/reperfusion) injury and the effects...
Clin Sci (Lond) (2008) 114 (4): 289–291.
Published: 15 January 2008
... secretion and ischaemia/reperfusion injury Clin. Sci. 2008 114 293 304 6 Kang D. H. Yoon K. I. Han D. S. Acute effects of recombinant human erythropoietin on plasma levels of proendothelin-1 and endothelin-1 in haemodialysis patients Nephrol. Dial. Transplant. 1998 13 2877...
Clin Sci (Lond) (2008) 114 (4): 293–304.
Published: 15 January 2008
.... Correspondence: Dr Chris Pemberton (email chris.pemberton@chmeds.ac.nz ). 8 10 2007 5 7 2007 13 9 2007 8 10 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 cardiac ischaemia endothelin erythropoietin (EPO) ischaemia/reperfusion injury natriuretic...
Clin Sci (Lond) (2006) 111 (6): 373–380.
Published: 14 November 2006
...Ismail H. Mallick; Marc C. Winslet; Alexander M. Seifalian IR (ischaemia/reperfusion) injury of the intestine occurs commonly during abdominal surgery. We have previously shown that PDTC (pyrrolidine dithiocarbamate), an HO-1 (haem oxygenase-1) donor, improves intestinal microvascular perfusion...
Clin Sci (Lond) (2006) 110 (6): 665–671.
Published: 15 May 2006
..., the effect of a human-like MS on the development of MI after temporary coronary occlusion (ischaemia/reperfusion injury) was studied. All experiments conducted on animals in this study were performed with approval from the Danish Institutional Animal Care and Use Committee. Male Sprague–Dawley...
Clin Sci (Lond) (2005) 109 (5): 465–473.
Published: 24 October 2005
...Giuseppe Fusai; George K. Glantzounis; Tarek Hafez; Wenxuan Yang; Alberto Quaglia; Hemant Sheth; Sanjeev Kanoria; Harry Parkes; Alexander Seifalian; Brian R. Davidson Steatotic livers are highly susceptible to I/R (ischaemia/reperfusion) injury and, therefore, the aim of the present study...
Clin Sci (Lond) (2005) 108 (1): 55–63.
Published: 15 December 2004
...Rahul S. KOTI; Wenxuan YANG; Georgios GLANTZOUNIS; Alberto QUAGLIA; Brian R. DAVIDSON; Alexander M. SEIFALIAN IPC (ischaemic preconditioning) may protect the steatotic liver, which is particularly susceptible to I/R (ischaemia/reperfusion) injury. Hepatic steatosis was induced in Sprague–Dawley...