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Poul F. GEERTSEN, Hans VON DER MAASE, Niels Vidiendal OLSEN, Niels FOGH-ANDERSEN, Steen Levin NIELSEN, Paul P. LEYSSAC
Clin Sci (Lond) (1998) 95 (1): 73–81.
Published: 01 July 1998
...Poul F. GEERTSEN; Hans VON DER MAASE; Niels Vidiendal OLSEN; Niels FOGH-ANDERSEN; Steen Levin NIELSEN; Paul P. LEYSSAC 1. Renal haemodynamics, lithium and sodium clearance were measured in 14 patients treated with recombinant interleukin-2 for metastatic renal cell carcinoma. 2. Patients were...
Clin Sci (Lond) (1995) 89 (5): 511–519.
Published: 01 November 1995
...- and sevenfold increment in T cells and a 17- and eightfold increment in large granular lymphocyte proliferative response. 3. Both cell types internalized more lipoprotein when they were stimulated with interleukin 2. Chylomicrons and low-density lipoprotein internalization was increased threefold and very low...
Clin Sci (Lond) (1994) 87 (5): 513–518.
Published: 01 November 1994
...D. J. Deehan; S. D. Heys; J. Broom; O. Eremin; P. H. Whiting 1. The T-cell-derived cytokine interleukin-2 may be used to reverse the immune suppression associated with major surgery. However, both major surgical procedures and recombinant interleukin-2 therapy are known to induce renal dysfunction...
Clin Sci (Lond) (1994) 86 (6): 671–675.
Published: 01 June 1994
... was measured in healthy subjects and in patients with metastatic colorectal cancer before and during infusion of recombinant interleukin-2. Rates of protein synthesis were compared with thymidine uptake in vitro and phenotypic analysis of lymphocytes. 2. The median rate of lymphocyte protein synthesis in four...
Felix Stockenhuber, Michaela Keil, Christian Wurnig, Robert W. Kurz, Michael Gottsauner-Wolf, Peter Balcke
Clin Sci (Lond) (1994) 86 (5): 633–638.
Published: 01 May 1994
...Felix Stockenhuber; Michaela Keil; Christian Wurnig; Robert W. Kurz; Michael Gottsauner-Wolf; Peter Balcke 1. Serum levels of erythropoietin and the immune parameters tumour necrosis factor-α, soluble interleukin-2 receptor, interleukin-2, interleukin-6 and interferon-γ were measured in patients...
Clin Sci (Lond) (1992) 82 (6): 695–700.
Published: 01 June 1992
... by fatty acids was similar to that previously reported for rat lymphocytes with one exception: oleate did not inhibit human lymphocyte proliferation. 5. The proliferation of T-lymphocytes is dependent upon their ability to synthesize and secrete the cytokine, interleukin-2. In the presence of mitogen...
Clin Sci (Lond) (1989) 76 (3): 261–263.
Published: 01 March 1989
... interleukin-1α (10 4 –10 5 units) implants induced a qualitatively similar but less intense response. 3. In contrast, recombinant human interleukin-2 (10 2 –10 4 units) implants resulted in early lymphocytic vasculitis (4 days) and the development of a predominantly lymphoid lesion comprised of lymphoblasts...