... of human regulatory T cells (Tregs) and human B cells and reduced serum human interferon-γ compared with saline treatment prior to development of clinical GVHD (day 21). To confirm the therapeutic benefit of P2X7 antagonism, NSG mice were injected i.p. with 10 × 10 6 hPBMCs (day 0), then daily...

... Commons Attribution License 4.0 (CC BY-NC-ND) . Autoinflammatory Interferonopathy inflammasome interferon Periodic Fever Syndrome The phrase ‘ autoinflammatory disease ’ was proposed as an alternative to ‘ autoimmune disease ’ by McDermott et al. [ 1 ] in the paper identifying...