... enhancing cancer progression. Immunotherapy has become a promising tool for cancer treatment as it restores the anti-tumour response of the patient’s immune system. Immune checkpoint inhibitors are the most widely studied immunotherapies worldwide and are now approved for multiple cancers. However, chimeric...

...) immunotherapy ischaemia/reperfusion injury regulatory T-lymphocytes (Tregs) Tregs are a subset of T-cells with an immunomodulatory function, commonly identified by their expression of CD4 and CD25 on the cell surface and the transcription factor Forkhead box P3 (Foxp3) in the nucleus [ 5...

... when stimulated with LPS. In conclusion, CBSC-derived DCs have the ability to induce stronger antigen-specific immunity and more potent anti-tumour effects and therefore could be a good source of DCs for use in DC-based cancer vaccines and immunotherapy. UCB was obtained from the National Taiwan...

...Juliet C. Gray; Peter W. M. Johnson; Martin J. Glennie The aim of cancer immunotherapy is to employ the specificity of the immune system to provide a more effective, less toxic, treatment compared with conventional therapies. Although many strategies have been used to try to generate effective...

... for Lung Health, University of Leicester, Glenfield General Hospital, Groby Road, Leicester LE3 9QP, U.K. 24 11 1999 10 3 2000 17 5 2000 The Biochemical Society and the Medical Research Society © 2000 2000 immunotherapy peptide epitopes streptokinase resistance T cells...