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Keywords: immunomodulation
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Articles
Clin Sci (Lond) (2022) 136 (6): 435–454.
Published: 29 March 2022
... for this article was enabled by the participation of Karolinska Institute in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society. atherosclerosis cardiovascular disease immunometabolism immunomodulation macrophages T-cells Atherosclerosis is the main...
Articles
Clin Sci (Lond) (2022) 136 (5): 383–404.
Published: 11 March 2022
...) . chemotherapy resistance DNA synthesis and repair genome integrity immunomodulation mutagenesis oncogenesis Cancer sequencing studies have yielded a repository of genomic data of an extraordinary scale, which is growing by the day. Major catalogs of tumor genomes include The Cancer Genome Atlas...
Includes: Supplementary data
Articles
Articles
Clin Sci (Lond) (2021) 135 (11): 1389–1408.
Published: 04 June 2021
... by the participation of King’s College London in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. cholesterol immune system immunometabolism immunomodulation Inflammation metabolism Cholesterol metabolism...
Articles
Clin Sci (Lond) (2021) 135 (9): 1065–1082.
Published: 07 May 2021
... immunomodulation lymphocytes mesenchymal stem cells   Although it is still a matter of intense debate [ 15 ], experimental autoimmune encephalomyelitis (EAE) is the experimental model for studying MS. It is induced by murine immunization with an emulsion of myelin-derived epitopes, as MOG, MBP and PLP...
Articles
Clin Sci (Lond) (2021) 135 (5): 703–724.
Published: 09 March 2021
... heart failure immunomodulation Correspondence: Mandar A. Aras ( mandar.aras@ucsf.edu ) 28 12 2020 22 02 2021 24 02 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Adaptive immune responses are key...
Articles
Clin Sci (Lond) (2020) 134 (21): 2807–2822.
Published: 03 November 2020
... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 immunomodulation Platelets Thrombocytopenia Platelets are anucleate blood cells produced by megakaryocytes resident in bone marrow and possibly the lung. They are approximately 2 µm in diameter...
Articles
Clin Sci (Lond) (2019) 133 (21): 2143–2157.
Published: 08 November 2019
... A immunomodulation mesenchymal stem cell rejection T-cells Current transplantation medicine has advanced understanding of the mechanisms of transplantation rejection, and a significant improvement has been achieved in the suppression of early graft failure. However, long-term survival rates have remained...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (2): 295–312.
Published: 25 January 2018
... 21 11 2017 22 11 2017 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 bariatric surgery immunomodulation inflammation obesity pregnancy placenta Obesity in women leads to reproductive difficulties that include oligo...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (1): 43–67.
Published: 05 January 2018
... of the immune system has grown exponentially in recent years. A large number of molecules and their roles in autoimmunity are being elucidated, but our understanding is still incomplete [ 5 – 8 ]. autoimmunity Autoreactive lymphocytes immunomodulation Immune tolerance molecular basis of health...
Articles
Clin Sci (Lond) (2017) 131 (21): 2627–2642.
Published: 27 October 2017
... immunotherapies in the form of immune checkpoint inhibitors were developed, mRCC was one of the first solid tumours to be tested in clinical trials. cancer immunomodulation immunology Renal cell cancer (RCC) accounts for 2–3% of all the adult cancers [ 1 ]. The incidence of RCC has been steadily...
Articles
Clin Sci (Lond) (2015) 129 (12): 1173–1193.
Published: 11 November 2015
.... Correspondence: Professor Tiziana Crepaldi (email tiziana.crepaldi@unito.it ). 17 7 2015 21 9 2015 30 9 2015 © 2015 Authors; published by Portland Press Limited 2015 angiogenesis cardioprotection fibrosis HGF/Met immunomodulation regeneration Growth factors...
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Clin Sci (Lond) (2014) 126 (9): 593–612.
Published: 14 January 2014
... family)], chemokine receptors, IL-17, TGFβ and other cytokines. Correspondence: Professor Ilja Striz (email ilja.striz@ikem.cz ). 16 8 2013 18 10 2013 22 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cytokine immunomodulation mucosal...
Articles
Clin Sci (Lond) (2013) 125 (7): 329–340.
Published: 07 June 2013
... cytometric analysis was performed with a fluorescence-activated cell sorter (FACS; FACSCalibur, Becton Dickinson), and the data were analysed with CellQuest software. The results were analysed using WinMDI software. α lipoic acid experimental autoimmune encephalomyelitis immunomodulation multiple...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2013) 124 (11): 651–662.
Published: 15 February 2013
... of HDACIs in these diseases, with a focus on their effects on cancer, fibrosis, inflammation and immunomodulation and metabolic disorders ( Table 1 ). Table 1 Applications of HDACIs in various disease models EGR-1, early growth response gene 1; ERK, extracellular-signal-regulated kinase; mTOR...
Articles
Clin Sci (Lond) (2011) 121 (12): 523–544.
Published: 22 August 2011
...@fbioyf.unr.edu.ar ). 12 4 2011 27 6 2011 6 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 bile acid cell death cholestasis hepatocellular transporter immunomodulation ursodeoxycholic acid (UCDA) UDCA (ursodeoxycholic acid) is currently the most...
Articles
Clin Sci (Lond) (2006) 110 (4): 393–407.
Published: 15 March 2006
... these infections, as well as other neuro-inflammatory conditions. dementia encephalitis HIV immunomodulation inflammation neuropathogenesis Although many viruses affect the brain and cause encephalitis, relatively little is known about the pathological mechanisms of these infections. Frequently...