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Keywords: hypercholesterolaemia
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Clin Sci (Lond) (2017) 131 (14): 1561–1578.
Published: 30 June 2017
... vascular risk factors–diabetes, hypercholesterolaemia, hypertension and smoking–are implicated as risk factors for VaD. The associations between cholesterol and small vessel disease (SVD), stroke, cognitive impairment and subsequent dementia are complex and as yet not fully understood. Similarly...
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Clin Sci (Lond) (2015) 129 (12): 1151–1161.
Published: 30 October 2015
...Xina Xie; Xuhong Song; Song Yuan; Haitao Cai; Yequn Chen; Xiaolan Chang; Bin Liang; Dongyang Huang Hypercholesterolaemia and inflammation are correlated with atherogenesis. Orphan nuclear receptor NR4A1, as a key regulator of inflammation, is closely associated with lipid levels in vivo . However...
Includes: Supplementary data
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Clin Sci (Lond) (2007) 113 (11): 427–434.
Published: 01 November 2007
...Christopher C. T. Smith; Lee Stanyer; D. John Betteridge; Michael B. Cooper Cerebrovascular accumulation of Aβ (β-amyloid) occurs in aging and AD (Alzheimer's disease). Hypercholesterolaemia, which is associated with raised plasma LDL (low-density lipoprotein), may predispose to AD. Soluble Aβ...
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Clin Sci (Lond) (1999) 96 (2): 199–207.
Published: 01 February 1999
... 1999 1999 L-arginine hypercholesterolaemia pharmacokinetics 199Clinical Science (1999) 96, 199 207 (Printed in Great Britain) Pharmacokinetics of L-arginine during chronic administration to patients with hypercholesterolaemia Oranee TANGPHAO*, Stephan CHALON , Heitor MORENO JR Brian B...
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Clin Sci (Lond) (1998) 95 (3): 361–367.
Published: 01 September 1998
... improves basal or stimulated function of the nitric oxide (·NO) dilator system in patients with hypercholesterolaemia. 2. Seven subjects aged 47±3 (±S.E.M.) years with moderately elevated serum cholesterol concentrations (6.0±0.1 ;mmol/l) were given 4 weeks of placebo therapy followed by 500 i.u...
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Clin Sci (Lond) (1991) 80 (2): 119–129.
Published: 01 February 1991
... be part of a general deleterious effect to the endothelium of hypercholesterolaemia. 2. This possibility has been investigated in vitro by measuring the response to acetylcholine, sodium nitroprusside, 5-hydroxytryptamine and noradrenaline in segments of aorta and of femoral, mesenteric and cerebral small...
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Clin Sci (Lond) (1984) 67 (4): 439–444.
Published: 01 October 1984
... reductions in circulating cholesterol induced by HMG warrant further investigation into the use of this compound in the management of familial hypercholesterolaemia. 27 2 1984 29 3 1984 © 1984 The Biochemical Society and the Medical Research Society 1984 cholestyramine 3-hydroxy-3...
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Clin Sci (Lond) (1983) 64 (6): 637–642.
Published: 01 June 1983
...Gerald Brook; Giora Winterstein; Michael Aviram 1. Repeated plasma exchange was carried out on three young patients with severe familial hypercholesterolaemia. There was a 3 week interval between each exchange. After a single exchange, plasma cholesterol, apolipoprotein B and low density...
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Clin Sci (Lond) (1979) 56 (4): 377–380.
Published: 01 April 1979
...Gillian M. Martin; P. Nestel 1. Possible defects in cholesterol metabolism were sought in children with familial hypercholesterolaemia. 2. In nine affected children (eight heterozygotes and one homozygote) and in five healthy children, cholesterol synthesis and bile acid synthesis were determined...
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Clin Sci Mol Med (1976) 51 (s3): 37s–39s.
Published: 01 December 1976
... atherosclerosis genetic factor hypercholesterolaemia hypertension Clinlcal Science and Molecular Medicine (1916) 51, 319-39s. Importance of hypertension and genetic factors for atherogenesis in rats Y. YAMORI,*t R. HORIE,*S H . HANDA Y. NARA,*t M. OHTAKAIS AND M. FUKASE* *Japan Stroke Prevention Center...
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Clin Sci Mol Med (1974) 47 (6): 547–557.
Published: 01 December 1974
...-esterified cholesterol within VLDL, and an increased efflux of cholesterol from plasma within LDL. 9 5 1974 © 1974 The Biochemical Society and the Medical Research Society 1974 bile acid colestipol hyperlipoproteinaemia hypercholesterolaemia lipoprotein Clinical Science and Molecular...