... human saphenous vein hydrogen peroxide nNOS • H 2 O 2 has been identified as the EDHF in human coronary arteries and, although NO and PGI 2 are more important for the HCA of healthy subjects, H 2 O 2 is gaining importance in disease states. nNOS is present in most vascular tissues...

... the involvement of nNOS (neuronal nitric oxide synthase) and H 2 O 2 (hydrogen peroxide) in the impaired endothelium-dependent vasodilation of the mesenteric arteries of DOCA (deoxycorticosterone acetate)-salt-hypertensive mice. Myograph studies were used to investigate the endothelium-dependent vasodilator...

..., hydrogen peroxide (H 2 O 2 ) and hypochlorous acid. Under pathological conditions, NOX-2 activity has been implicated in the development of autoimmunity, indicating a role in modulating lymphocyte effector function. Notably, T-cell clonal expansion and subsequent cytokine production requires a metabolic...

... © 2011 Biochemical Society 2011 endothelium hydrogen peroxide NADPH oxidase (Nox) reactive oxygen species superoxide vascular smooth muscle cell ROS (reactive oxygen species) are produced in all layers of the vascular wall by all vascular cell types, including endothelial, smooth...

... (prostaglandin F 2α ) receptors, 10μmol/l] or SQ29584 [antagonist of PGH 2 (prostaglandin H 2 )/TXA 2 receptors, 3μmol/l]. The effect of tiron (1 mmol/l) and catalase (300 units/ml) were also evaluated on phenylephrineinduced contraction. aorta calcium hydrogen peroxide prostanoid reactive oxygen...

... ] and expressed as units/mg of protein. antioxidant catalase hydrogen peroxide ovine myocardium superoxide The concept that an adverse intrauterine environment can affect the risk of developing cardiovascular disease later in life was initially suggested by epidemiological studies...

... glutamine hydrogen peroxide neutrophil nitric oxide ornithine 2-oxoglutarate polyamines superoxide anion. 287Clinical Science (2002) 102, 287 295 (Printed in Great Britain) Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide...

... 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 amino acids free radicals hydrogen peroxide parenteral nutrition phototherapy riboflavin C h i d Science (1993) 85, 7W712 (Printed in Great Britain) Hydrogen peroxide generation in a model paediatric...

... The Biochemical Society and the Medical Research Society 1993 cell proliferation hydrogen peroxide interleukin-6 mesangial cells platelet-derived growth factor reactive oxygen species Clinical Science (1993) 115, 747-751 (Printed in Great Britain) 747 Interactions of hydrogen peroxide...

...H. A. Kleinveld; W. Sluiter; A. M. C. Boonman; A. J. G. Swaak; C. E. Hack; J. F. Koster 1. The effect of free-radical-altered IgG (monomer and polymer u.v.-irradiated IgG), compared with that of native and heat-aggregated IgG, on the production rate of superoxide anion and hydrogen peroxide...

.... The extracellular release of hydrogen peroxide (H 2 O 2 ) by human alveolar macrophages (AM) has been measured. AM were obtained by bronchoalveolar lavage and adherence from 24 smokers and 17 non-smokers. 3. Smokers' AM released significantly more H 2 O 2 (3.83 nmol h −1 üg −1 of DNA; sem 0.44) than those of non...

...D. A. Rowley; B. Halliwell 1. Superoxide and hydrogen peroxide are formed by activated phagocytes and react together in the presence of iron salts to form the hydroxyl radical, which attacks hyaluronic acid. Ascorbic acid also interacts with hydrogen peroxide and iron salts to form hydroxyl radical...

...D. R. Blake; N. D. Hall; D. A. Treby; B. Halliwell; J. M. C. Gutteridge 1. On exposure of synovial fluid to superoxide and hydrogen peroxide, generated enzymically or by activated polymorphonuclear leucocytes, hyaluronic acid is depolymerized and the fluid loses its lubricating properties...

... . It is unlikely that an appreciable proportion of this oxygen is incorporated into the organic composition of the cell or of the ingested microorganism. 3 3 1978 22 6 1978 © 1978 The Biochemical Society and the Medical Research Society 1978 granulocytes hydrogen peroxide leucocytes...